No-pruritus: Causes & Reasons

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Possible Causes for no pruritus

Vulvitis

Zoon's vulvitis is a rare, chronic condition of the vulva that presents with burning, pruritus, and dysuria with characteristic lesions and histopathology. [ncbi.nlm.nih.gov]

Links: specific infections secondary vulvitis vulval sensitivity dermatitis diagnosis Bartholin's abscess pruritus vulvae [gpnotebook.com]

[…] barrier is reduced in cases of vulval atrophy or degeneration resulting from: the low oestrogen levels after the menopause vulval dysplasia Many of these conditions result in pruritus [gpnotebook.com]

Atopic Dermatitis

[…] been used in clinic to relieve pruritus of atopic dermatitis patients. [ncbi.nlm.nih.gov]

[…] remains as unmet needs mainly due to the distinctive multifactorial pathogenesis of pruritus in atopic dermatitis. [doi.org]

Key search terms included: atopic dermatitis, pruritus, and IL-31. [ncbi.nlm.nih.gov]

Vaginal Candidiasis

RESULTS: Of the 464 women examined, 177 (38.1%) had abnormal vaginal discharge, 68(14.7%) had genital ulcers, 272 (58.6%) had genital pruritus, 18 (3.9%) had genital warts [ncbi.nlm.nih.gov]

Presence of Candida vaginitis was based upon the specification as such by investigators, the presence of specific symptoms such as genital pruritus and/or the prescription [ncbi.nlm.nih.gov]

Vulval pruritus 300 (75.0%) was significantly related to abnormal vaginal discharge (P 0.001). The prevalence of C. albicans was 41%. [ncbi.nlm.nih.gov]

Vaginitis

Vaginal discharge, sometimes bloody, and pruritus are the most common symptoms. [ncbi.nlm.nih.gov]

Discharge due to vaginitis is accompanied by pruritus, erythema, and sometimes burning, pain, or mild bleeding. Pruritus may interfere with sleep. [msdmanuals.com]

CASE REPORT: A 48-year-old postmenopausal woman, with a history of hysterectomy with several comorbidities, presented with a 4-month history of bloody discharge and vulvar pruritus [ncbi.nlm.nih.gov]

Dermatitis

Symptoms and Signs Symptoms of exfoliative dermatitis include pruritus, malaise, and chills. [merckmanuals.com]

Skin areas affected by active eczema in flare should receive daily anti-inflammatory therapy first before introducing emollients, to induce rapid relief of skin lesions and pruritus [ncbi.nlm.nih.gov]

Intense pruritus is a key feature. [merckmanuals.com]

Cholestatic Jaundice

Pruritus is the least in the morning as pruritus factor is stored in gallbladder overnight during the morning. [ncbi.nlm.nih.gov]

Medical Management Pruritus In cases of obstructive physiology, pruritus is relieved within 24 to 48 hours of biliary decompression. For other cases. [ncbi.nlm.nih.gov]

Prominent features of cholestasis are pruritus and malabsorption of fat and fat-soluble vitamins. [ncbi.nlm.nih.gov]

Contact Dermatitis

Ignoring other conditions can prolong pruritus unnecessarily. [ncbi.nlm.nih.gov]

We describe two cases of acute-onset erythema, peeling, and pruritus or tenderness isolated to the palmar surface of the hands. [ncbi.nlm.nih.gov]

Genital ACD can present acutely with erythematous erosions and pruritus or chronically with lichenification. [ncbi.nlm.nih.gov]

Cholangitis

Pruritus was the most common adverse event; 15% (OCA 10 mg) and 38% (OCA 50 mg) discontinued due to pruritus. [ncbi.nlm.nih.gov]

[…] weeks primigravida was referred from the Emergency Department to the Medical Unit Khyber Teaching Hospital-MTI, Peshawar with four weeks of fever, progressive jaundice, pruritus [ncbi.nlm.nih.gov]

A comprehensive article on pruritus is as follows: "Pruritus" (American Family Physician). [psc-literature.org]

Familial Hypercholanemia

Diseases related with Failure to thrive and Pruritus In the following list you will find some of the most common rare diseases related to Failure to thrive and Pruritus that [mendelian.co]

Affiliated tissues include liver, and related phenotypes are pruritus and failure to thrive [malacards.org]

Increased serum bile acid concentration Vitamin K deficiency Abnormality of the abdomen Steatorrhea Abnormality of the digestive system Steatorrhea Abnormality of the integument Pruritus [familydiagnosis.com]

Pruritic Urticarial Papules and Plaques of Pregnancy

Moderate or intense pruritus was present in all but one case. [ncbi.nlm.nih.gov]

Although pruritus was the major complaint of all patients, excoriations were very rare. [ncbi.nlm.nih.gov]

Undetermined-- Localisation Trunk / abdomen Primary Lesions Papule / erythematous Plaque / erythematous Pathophysiology pregnancy-related dermatoses urticaria Symptoms Pruritus [dermquest.com]

Cholestasis

Intractable pruritus of cholestasis leads to significant morbidity. [ncbi.nlm.nih.gov]

Abstract Accumulation of bile acids can lead to invalidating pruritus in cholestatic patients. [ncbi.nlm.nih.gov]

The pruritus of cholestasis is a maddening complication of liver disease. [ncbi.nlm.nih.gov]

Hemorrhoids

Non significant trends in favor of SH were seen in pain, pruritus ani, and fecal urgency. [ncbi.nlm.nih.gov]

right anterolateral and right posterolateral portions of the anal canal form haemorrhoids when the pads become enlarged and congested Haemorrhoids may cause: anal pain pruritus [gpnotebook.co.uk]

Table 7 Distribution of pruritus ani stages in 317 patients with pruritus ani and comparison of pruritus ani stages in 155 patients with exclusive pruritus ani vs.162 patients [ncbi.nlm.nih.gov]

Intertrigo

Applying barrier protectants reduces skin breakdown and alleviates pruritus and pain. [aafp.org]

[…] scroti L29.2 Pruritus vulvae L29.3 Anogenital pruritus, unspecified L29.9 Pruritus, unspecified L30 Other and unspecified dermatitis L30.0 Nummular dermatitis L30.1 Dyshidrosis [icd10data.com]

[…] entry point for micro-organisms that cause secondary infections. 7 Clinical Manifestations Intertrigo is often a chronic disorder that begins insidiously with the onset of pruritus [aafp.org]

Atrophic Vaginitis

Clinical findings Pruritus burning sensation, reduced vaginal secretions, dyspareunia, post-coital bleeding, bacterial infection. [medical-dictionary.thefreedictionary.com]

Vaginal or vulval dryness Vaginal or vulval itching (pruritus vulvae) Vaginal burning Painful sex (dyspareunia) Skin splitting (fissuring) of the entrance to the vagina (posterior [dermnetnz.org]

Vaginal or vulval dryness Vaginal or vulval itching ( pruritus vulvae ) Vaginal burning Painful sex ( dyspareunia ) Skin splitting (fissuring) of the entrance to the vagina [dermnetnz.org]

Primary Sclerosing Cholangitis

Jaundice and pruritus. Right upper quadrant abdominal pain. Fatigue, weight loss, fevers and sweats. [patient.info]

Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus. [ncbi.nlm.nih.gov]

A 45-year-old woman with the diagnosis of primary sclerosing cholangitis and ulcerative colitis admitted with the complaints of pruritus and jaundice. [ncbi.nlm.nih.gov]

Pityriasis Circinata

Pruritus (may be intense) is thought to occur in about half of cases. The rash begins with a herald patch in 40-76% of cases. [patient.info]

Five consecutive daily erythemogenic exposures resulted in substantially decreased pruritus and extent of disease greater than that on the untreated side in approximately [ncbi.nlm.nih.gov]

For pruritus the following may be tried: Emollients. Topical corticosteroid, with the potency depending on the severity of the itch. Topical menthol. [patient.info]

Urticaria

Pruritus is a common symptom of primary skin diseases including allergic contact dermatitis. [dentalcare.com]

Two trials demonstrated significant elimination of pruritus with second- or third-generation antihistamine treatment vs placebo (OR, 10.44; 95% CI, 4.39 to 24.84). [ncbi.nlm.nih.gov]

Inducible urticaria is a heterogeneous group of skin disorders characterized by the appearance of wheals, pruritus and/or angioedema, sometimes accompanied by systemic symptoms [ncbi.nlm.nih.gov]

Tinea Pedis

Improvements in patient quality of life (pruritus) and patient preference were measured using the pruritus visual analog scale (VAS), Skindex-16, and patient preference questionnaires [ncbi.nlm.nih.gov]

The pruritus visual analog scale (VAS) was used to assess the subjective symptom of itching. [ncbi.nlm.nih.gov]

Patients showed rapid improvement in pruritus as early as week 2, and at six weeks' follow up, all patients were free of erythema while 93.8 percent were free of pruritus; [ncbi.nlm.nih.gov]

Psychogenic Pruritus

Psychogenic pruritus is a common manifestation of chronic anxiety, usually a localized itch, especially in the anogenital area.The condition is often managed with drugs including [en.wikipedia.org]

Pruritus is an important factor in the development of epidermolysis bullosa pruriginosa and is the focus of management. [ncbi.nlm.nih.gov]

From Wikidata Jump to navigation Jump to search No description defined edit Language Label Description Also known as English Psychogenic pruritus No description defined Statements [wikidata.org]

Secondary Sclerosing Cholangitis

Later presentation includes abdominal pain, jaundice, pruritus, fever and bacterial cholangitis from ascending infection. [orpha.net]

Extramammary Paget Disease

Here, we report a 76-year-old man presented with pruritus in the perianal area. [ncbi.nlm.nih.gov]

Published: 03/09/2012 Authors: van der Schoot JHF and Roumen RM A 72-year-old man presented with a solitary eczematous perianal lesion causing a painful pruritus. [bjs.co.uk]

Pruritus is the most frequent complaint followed by a burning sensation. [alliedacademies.org]

Primary Biliary Cirrhosis

Intense pruritus can be itself an indication to liver transplantation, in extreme cases leading to suicide. [ncbi.nlm.nih.gov]

Chronic pruritus. N Engl J Med 2013;368:1625-1634. [karger.com]

Pruritus is a major symptom of primary biliary cirrhosis, cholestatic autoimmune disease which affects mostly middle-age women. [ncbi.nlm.nih.gov]

Biliary Cirrhosis

The case of a 78-year-old man with PBC who presented with pruritus is discussed. Liver biopsy and antimitochondrial antibody serology were diagnostic of early-stage PBC. [ncbi.nlm.nih.gov]

Pruritus, fatigue, and dry mouth and eyes are the initial symptoms in 50% of patients and can precede other symptoms by months or years. [merckmanuals.com]

Treatment includes ursodeoxycholic acid, obeticholic acid, cholestyramine (for pruritus), supplementary fat-soluble vitamins, and, ultimately for advanced disease, liver transplantation [msdmanuals.com]

Progressive Familial Intrahepatic Cholestasis

Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders. [ncbi.nlm.nih.gov]

Pruritus secondary to increased bile salts in the serum may not respond to medical treatment. [ncbi.nlm.nih.gov]

[…] month at 200 mg/kg/day and the next month at 350 mg/kg/day but partially restored BSEP expression at the canalicular membrane and significantly improved liver tests and pruritus [ncbi.nlm.nih.gov]

Pruritic Rash

pruritus. [clevelandclinicmeded.com]

What is pruritus ? Pruritus is the medical term for itch. [dermnetnz.org]

Explore pruritus cases such as: Pityriasis rosea on trunk, pruritus on leg, Pruritic rash on neck and chest All pruritus Cases Pityriasis rosea on trunk This rash represents [figure1.com]

Scabies

Severe itching (pruritus), especially at night, is the earliest and most common symptom of scabies. [cdc.gov]

Pruritus may be absent and typical scabies lesions may be concealed due to the preexisting disease, resulting in delayed diagnosis. [ncbi.nlm.nih.gov]

Itching (pruritus) may be absent in crusted scabies because of a patient’s altered immune status or neurological condition. [cdc.gov]

Lichen Sclerosus

Intense and recalcitrant pruritus is a symptomatic hallmark of LS. [liebertpub.com]

Micheline Moyal-Barracco, Pruritus Vulvae, Pruritus, 10.1007/978-1-84882-322-8_37, (243-252), (2009). Paul D. [doi.org]

[…] the characteristic clinical presentation and is preferably confirmed with histologic features of a 3-mm punch biopsy. 3 Several other disorders that present with vulvar pruritus [clinicaladvisor.com]

Bullous Pemphigoid

Three (20.0%) of 15 patients had only pruritus without primary skin lesions (pruritus sine materia). [jamanetwork.com]

Mean time to pruritus was similar for pembrolizumab and nivolumab at 19 and 21 weeks, respectively. [ncbi.nlm.nih.gov]

Abstract The number of elderly patients with chronic pruritus has been gradually increasing in aging countries. [ncbi.nlm.nih.gov]

Drug-induced Cholestatic Hepatitis

References Bunchorntavakul C, Reddy KR: Pruritus in chronic cholestatic liver disease. Clin Liver Dis 2012;16: 331–346. [karger.com]

Patients should be specifically asked about the presence of pruritus. In general, pruritus presents earlier in cases of intrahepatic cholestasis. [hepatitis.va.gov]

Signs and symptoms [ edit ] Itchiness ( pruritus ). [en.wikipedia.org]

Intrahepatic Cholestasis

Pruritus improved in 75/98 (76.5%) patients, and totally disappeared before delivery in 25/98 (25.5%). [ncbi.nlm.nih.gov]

We present two cases of pregnancy after IVF treatment diagnosed with ICP following the development of OHSS, deteriorating liver function tests and severe pruritus. [ncbi.nlm.nih.gov]

Partial external biliary diversion (PEBD) is pursued to improve pruritus and arrest disease progression. [ncbi.nlm.nih.gov]