Create issue ticket

122 Possible Causes for Nocturnal Leg Cramp, Paresthesia

  • Hypoglycemia

    Severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger; sweating; paresthesia; impaired mental function; seizures; coma[icd9data.com] […] discomfort Headache Abnormal thinking, impaired judgment Nonspecific dysphoria, moodiness, depression, crying, exaggerated concerns Feeling of numbness, pins and needles (paresthesia[en.wikipedia.org] […] level; clinical hypoglycemia has diverse etiologies; severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger, sweating, paresthesia[icd9data.com]

  • Peripheral Neuropathy

    Chemotherapy-induced peripheral neuropathy is a debilitating side effect of chemotherapy, which manifests as paresthesias, dysesthesias, and numbness in the hands and feet[ncbi.nlm.nih.gov] Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy.[ncbi.nlm.nih.gov] The primary manifestations of polyneuropathy are slowly progressive numbness and paresthesias, with burning sensations in the feet usually in a symmetrical pattern.[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    People suffering from alcoholic neuropathy may feel burning and tingling sensations in their feet, which may persist or may last from a few months to a few years.[foundationforpn.org] Peripheral neuropathy may be evidenced by muscular weakness, paresthesias, and decreased peripheral sensation.[mentalhealth.com] Symptoms include numbness, tingling and pain, muscle weakness usually in the extremities, loss of bladder or bowel control, impotence , diarrhea , nausea and vomiting, or[onhealth.com]

  • Chronic Kidney Insufficiency

    Uremia also causes polyneuropathy with paresthesia.[lecturio.com]

  • Restless Legs Syndrome

    Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org] As reported by patients, paresthesia and/or dysesthesia may range in severity from slightly unpleasant to extremely agonizing.[symptoma.com] Leg pain and discomfort are common complaints in any primary physician's clinic.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    The most common of these are paresthesias, weakness, clumsiness, and an unsteady gait.[web.archive.org] We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] The classic triad of weakness, sore tongue, and paresthesias may be elicited but usually is not the chief symptom complex.[web.archive.org]

  • Amyotrophic Lateral Sclerosis

    FDA bans quinine for nocturnal leg cramps. Drug Utilization Rev . 1995; Oct:150. 26. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M.[aafp.org] In 1994, his 46-year-old wife noted motor weakness with paresthesia in the lower limbs.[dx.doi.org] FDA bans quinine for nocturnal leg cramps. Drug Utilization Rev. 1995; Oct:150. 26. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M.[aafp.org]

  • Hypocalcemia

    At presentation, he had ataxia, paresthesia in the hands and feet, and abdominal cramping. Magnetic resonance imaging of the brain was unremarkable.[ncbi.nlm.nih.gov] A comparison between groups demonstrated that cases had a significantly higher incidence of symptomatic hypocalcemia resulting in paresthesia and tetany (38% vs. 0%; P CONCLUSIONS[ncbi.nlm.nih.gov] The symptoms that are highly suggestive of hypocalcemia are paresthesia and leg weakness, although you may still have hypocalcemia without those symptoms.[symcat.com]

  • Electrolytes Abnormal

    A few years ago, researchers in the United Kingdom found that 300 mg of supplemental magnesium reduced nighttime or nocturnal leg cramps in individuals who suffered chronic[eletewater.co.uk] […] malnutrition, starvation, diarrhea, prolonged NPO status, nasogastric suctioning, ethanol ingestion, Crohn's and celiac disease, certain drugs neuromuscular irritability, numbness, tingling[quizlet.com] Patients with significant deficiency may complain of muscle cramps, tetany, and paresthesias of the lips and extremities.[musculoskeletalkey.com]

  • Hypokalemia

    The earliest signs are weakness and muscle cramps and numbness and tingling that usually begin in the lower extremities.[medical-dictionary.thefreedictionary.com] GS most commonly manifests with muscle weakness, salt craving, thirst, nocturia, paresthesia (especially in the face), tetany, and abdominal pain ( 3 ).[clinchem.aaccjnls.org] Paresthesias, especially in the face, frequently occur.[orpha.net]

Further symptoms

Similar symptoms