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32 Possible Causes for Nocturnal Leg Cramp, Paresthesia, Paresthesia of Lower Extremity

  • Peripheral Neuropathy

    Chemotherapy-induced peripheral neuropathy is a debilitating side effect of chemotherapy, which manifests as paresthesias, dysesthesias, and numbness in the hands and feet[] Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy.[] The primary manifestations of polyneuropathy are slowly progressive numbness and paresthesias, with burning sensations in the feet usually in a symmetrical pattern.[]

  • Restless Legs Syndrome

    Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[] As reported by patients, paresthesia and/or dysesthesia may range in severity from slightly unpleasant to extremely agonizing.[] Vesper's curse" is a transient lumbar stenosis caused by venous plexus engorgement from increased right atrial filling pressure while lying down; the stenosis results in lower-extremity[]

  • Pernicious Anemia

    The most common of these are paresthesias, weakness, clumsiness, and an unsteady gait.[] We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[] The paresthesias usually first occur in the lower extremities. At this early stage there might be no objective signs on the neurological examination.[]

  • Respiratory Alkalosis

    Dry mouth Nausea/vomiting May exhibit: Abdominal distension (elevating diaphragm as with ascites, pregnancy) Vomiting NEUROSENSORY May report: Headache, tinnitus Numbness/tingling[] Neurological: Rapid decrements in PaCO2 to half the normal values or lower are typically accompanied by 1. paresthesias of the extremities, 2. chest discomfort, 3. circumoral[] […] seizures confusion hypo kalemia lightheadedness dizziness tingling of the extremities hope this helps.[]

  • Peripheral Vascular Disease

    Additional conditions to consider are acute embolism, deep or superficial venous thrombosis, restless legs syndrome, systemic vasculitides, nocturnal leg cramps, muscle or[] Pentoxifylline 800 mg/d was found to be effective in improving the symptoms in patients with noninsulin-dependent diabetes mellitus, including improvement in walking distance, paresthesia[] Paresthesia at rest may be indistinguishable from that due to diabetic neuropathy, although in the latter the paresthesia is usually bilateral, symmetrical, and with a "sock[]

  • Alcoholic Neuropathy

    Depending on the level of nerve damage in diabetic and alcoholic neuropathy (polyneuropathy) damage sensitivity (numbness, tingling, burning, and "goose"), pain and muscle[] Initial symptoms of alcoholic polyneuropathy are usually found in the lower extremities ( Ammendola et al ., 2001 ) and can affect both the sensory (numbness, paresthesia,[] Clinical manifestations include variable degrees of weakness; atrophy; paresthesias; pain; loss of reflexes; sensory loss; diaphoresis; and postural hypotension.[]

  • Spinal Cord Lesion

    Specific symptoms depend on the site of injury. e.g. posterior horn or column injury produces paresthesias, pain and other sensory disturbances; anterior horn or corticospinal[] The symptomatology (symptoms and signs) of spinal cord compression consists of sensory (pain, numbness and paresthesia), motor and autonomic disturbances, the nature and extend[] Numbness, paresthesias, and/or weakness from one level on down is indicative of a cord lesion.[]

  • Spinal Stenosis

    Patients with LSS also can report nocturnal leg cramps and neurogenic bladder symptoms. Symptoms can be unilateral or more commonly bilateral and symmetrical.[] Paresthesia (or paraesthesia ) is an abnormal dermal sensation (e.g., a tingling, pricking, chilling, burning, or numb sensation on the skin) with no apparent physical cause[] Both patients complained of paresthesias and weakness in their lower extremities on postoperative day 1.[]

  • Deep Vein Thrombosis

    Abstract A previously healthy 21-year-old man presented with back pain, bilateral extremity pain, and right lower extremity weakness, paresthesias, and swelling.[] A 69-year-old woman complained of severe left leg weakness with paresthesia.[] Some symptoms of post-thrombotic syndrome are pain, edema, paresthesia, and in severe cases, leg ulcers.[]

  • Spastic Paraplegia

    Paresthesia Paresthesia in lower extremity can recognized in pure HSP.. Paresthesia Paresthesia in lower extremity can recognized in pure HSP..[] […] as C7 root involvement causes loss of the triceps reflex, pain and/or paresthesias radiating to the middle finger and weakness of the triceps muscle.[] These symptoms can include: Leg cramps Paresthesia Muscle spasms Highly arched feet Bladder control problems Relatively mild muscle wasting Diminished vibration sense in the[]

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