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23 Possible Causes for Nocturnal Leg Cramp, Paresthesia, Prolonged QT Interval

  • Chronic Kidney Insufficiency

    Uremia also causes polyneuropathy with paresthesia.[lecturio.com]

  • Hypocalcemia

    Hypocalcemia is a potentially fatal electrolyte imbalance with complications that include seizures, tetany, prolonged QT interval, cardiomyopathy, and congestive heart failure[ncbi.nlm.nih.gov] At presentation, he had ataxia, paresthesia in the hands and feet, and abdominal cramping. Magnetic resonance imaging of the brain was unremarkable.[ncbi.nlm.nih.gov] EMAIL PRINT SAVE EMAIL SAVE The ECG findings of hypocalcemia include: A prolonged QT interval A lengthened ST segment There are many causes of a prolonged QT interval on the[healio.com]

  • Hypokalemia

    QT interval may be seen, which is actually the QU interval with an absent T wave. 1 Severe hypokalemia can also cause a variety of tachyarrhythmias, including ventricular[doi.org] The earliest signs are weakness and muscle cramps and numbness and tingling that usually begin in the lower extremities.[medical-dictionary.thefreedictionary.com] SCN5A-1103Y was associated with QT interval prolongation (2.7 milliseconds; P .001) and potentiated the effect of hypokalemia on QT interval prolongation (14.6 milliseconds[ncbi.nlm.nih.gov]

  • Hypomagnesemia

    The others had electrocardiogram abnormalities (prolonged QT interval, ST depression, and U waves).[ncbi.nlm.nih.gov] […] deficiency associated with proton pump inhibitors (PPIs) has been described recently with clinical presentations varying from life-threatening conditions to muscle cramps and paresthesias[ncbi.nlm.nih.gov] Her electrocardiogram disclosed typical, prolonged QT interval, ST depression, and U waves.[ncbi.nlm.nih.gov]

  • Hypoglycemia

    Severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger; sweating; paresthesia; impaired mental function; seizures; coma[icd9data.com] In addition, there have been studies linking methadone treatment to QT interval prolongation and torsade de pointes.[ncbi.nlm.nih.gov] […] discomfort Headache Abnormal thinking, impaired judgment Nonspecific dysphoria, moodiness, depression, crying, exaggerated concerns Feeling of numbness, pins and needles (paresthesia[en.wikipedia.org]

  • Electrolytes Abnormal

    The most common finding on EKG in patients with hypocalcemia is a prolonged QT interval without any further changes.[cdemcurriculum.com] A few years ago, researchers in the United Kingdom found that 300 mg of supplemental magnesium reduced nighttime or nocturnal leg cramps in individuals who suffered chronic[eletewater.co.uk] […] malnutrition, starvation, diarrhea, prolonged NPO status, nasogastric suctioning, ethanol ingestion, Crohn's and celiac disease, certain drugs neuromuscular irritability, numbness, tingling[quizlet.com]

  • Graves Disease

    Treatment The goals of treatment ( 18 – 20 ) are elimination of the symptoms and signs of hypoparathyroidism (paresthesiae, muscle cramps, convulsions, stridor, cognitive[doi.org]

  • Electrolyte Imbalance

    Prolonged QT interval D. Shortened ST segment 68. A. Prominent U waves B. Prolonged PR interval C. Depressed ST segment D. Widened QRS complexes 69. A. Alcoholism B.[proprofs.com] A few years ago, researchers in the United Kingdom found that 300 mg of supplemental magnesium reduced nighttime or nocturnal leg cramps in individuals who suffered chronic[eletewater.co.uk] Hypokalemia GI hyperactivity, diarrhea, irritability, apathy, confusion, muscle weakness/ areflexia, irregular pulse , decreased h.r, paresthesias, extremity numbness.[memorize.com]

  • Quinine Poisoning

    An ECG would indicate the development of a prolonged QT interval and the risk of dysrhythmias.[southsudanmedicaljournal.com] Article date: June 2010 Quinine has been used in the UK for the treatment of nocturnal leg cramps for many years.[gov.uk] Neurological Ataxia, paresthesias. Convulsions may follow an overdose. Central nervous system toxicity seems to be more marked in children than adults.[inchem.org]

  • Hypokalemic Periodic Paralysis

    QT interval.[medicinenet.com] Before cardiac side effects would occur, osmotic diarrhea and paresthesia of the lips, hands, and feet typically intervene.[translational-medicine.com] […] of a prolonged QT interval.[flipper.diff.org]

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