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52 Possible Causes for Nocturnal Leg Cramp, Peripheral Neuropathy, Toe Pain

  • Peripheral Neuropathy

    Peripheral Neuropathy symptoms usually start with numbness, prickling or tingling in the toes or fingers.[foundationforpn.org] […] management of generic peripheral neuropathy.[doi.org] Most of the time the problem starts in the fingers and toes. As it gets worse, it moves into the limbs, causing pain and loss of feeling in the feet, legs, and hands.[stanfordhealthcare.org]

  • Alcoholic Neuropathy

    Valengilda/iStock Boozing Can Cause Gout Gout is a type of arthritis that affects the big toe, causing excruciating pain, redness and swelling.[footfiles.com] Prognosis of alcoholic peripheral neuropathy.[jnnp.bmj.com] […] weakness, (“painful legs and moving toes”) and, in severe cases, the same symptoms in fingertips and hands (giving the so-called “stocking and glove” pattern) [13,14,15].[nutrientsreview.com]

  • Peripheral Vascular Disease

    PAIN IN TOES OR FEET WHILE RESTING If you have pain in your toes or feet while resting, you may have an advancing case of PAD.[vascular.org] Additional conditions to consider are acute embolism, deep or superficial venous thrombosis, restless legs syndrome, systemic vasculitides, nocturnal leg cramps, muscle or[aafp.org] […] arteriosclerosis obliterans, peripheral neuropathy, cellulitis, and osteomyelitis and the failing heart.[ncbi.nlm.nih.gov]

  • Restless Legs Syndrome

    Radiculopathy: Spinal cord injury can cause a variety of unilateral or bilateral symptoms in the lower extremities including painful legs and flexion/extension of the toes[clinicaladvisor.com] Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org] Parkinsonism [adjusted odds' ratio (adj-OR) 7.4 (95% CI: 5.3-10.4)], peripheral neuropathy [adj-OR 3.7 (95% CI: 3.3-4.1)], subjective cognitive impairment (SCI) [adj-OR 3.1[ncbi.nlm.nih.gov]

  • Ischemic Peripheral Neuropathy

    Therapy may also include pain relievers, calcium channel blockers, quitting smoking, and avoiding cold temperatures and emotional upset.[texasheart.org] ” for nocturnal cramps.[vasculardiseasemanagement.com] Depending on the disease associated with ischemic neuropathy, a mononeuropathy or a sensory-motor, axonal-demyelinating peripheral neuropathy may be seen as well.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    […] shortness of breath (known as ‘the sighs’) Sore tongue Low grade fevers Difficulty in proprioception Difficulty concentrating and sluggish responses, brain fog Neuropathic pain[revivelifelab.com] Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[clinlabnavigator.com] Cobalamin deficiency–related neurological impairment can vary in clinical presentation, including acute combined system degeneration, peripheral neuropathy, and psychosis.[emedicine.medscape.com]

  • Diabetic Peripheral Neuropathy

    Moreover, effective pain management can be achieved for patients who complain of general pain of the sole, including the toe, by attaching scrambler patches around the ankle[ncbi.nlm.nih.gov] Diabetic peripheral neuropathy, one form of diabetic neuropathy, affects the arms, hands, fingers, legs and feet.[symptoma.com] Numbness, tingling, or pain in the toes, feet, legs, hands, arms, and fingers Indigestion, nausea, or vomiting Diarrhea or constipation Dizziness or faintness due to a drop[peripheralneuropathycenter.uchicago.edu]

  • Nocturnal Leg Cramp

    Photo: Getty Images Enjoying a good night’s sleep only to be awakened by a painful cramp or spasm in your calf, thigh, or toe?[empowher.com] Nocturnal leg cramps. Am Fam Physician. 2012;86(4):350-355. Butler JV, Mulkerrin EC, et al. Nocturnal leg cramps in older people. Postgrad Med J. 2002;78:596-598.[stjosepheureka.myhospitalwebsite.com] […] disease, and peripheral neuropathy.[aafp.org]

  • Spastic Paraplegia

    My toes were always curled under my feet. My gait and balance were very poor. There was always neck pain at the c-5 bulge.[rxmarijuana.com] The aim of this study was to identify the genetic cause of the disease in an Italian family with spastic paraplegia and peripheral neuropathy.[ncbi.nlm.nih.gov] […] and relaxation of muscle groups (clonus), and upward extension of the toes when the foot is stroked (Babinski’s sign).[medschool.lsuhsc.edu]

  • Pes Planus

    It presents with leg oedema, pain, nocturnal cramping, venous claudication, skin pigmentation, dermatitis and ulceratiaion (usually on the medial aspect of the lower leg).[slideshare.net] Anterior knee pain was diagnosed when symptoms were attributed to the patellofemoral joint.[ncbi.nlm.nih.gov] Peripheral neuropathy is a functional disturbance or pathological change in the nervous system supplying the foot, including peripheral neuropathy due to diabetes mellitus[veterans.gc.ca]

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