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51 Possible Causes for Nocturnal Leg Cramp, Somnolence

  • Restless Legs Syndrome

    The main side effects were dizziness, somnolence, headache, and irritability.[ncbi.nlm.nih.gov] Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org] Placebo comparisons showed a significantly higher incidence of nausea for pramipexole (p 0.01), whereas nausea, vomiting, dizziness, and somnolence were significantly higher[ncbi.nlm.nih.gov]

  • Hypoglycemia

    Nocturnal attacks are often preceded by nightmares and cause severe sleep disturbance resulting in daytime somnolence. Only a perfect diet will control hypoglycemia.[fibromyalgiatreatment.com] This is seen in people with diabetes treated with insulin who may show reduction in spontaneous movements and speech, somnolence, poor thinking and work performance, changes[patient.info] In newborns, hypoglycemia can produce irritability, jitters, myoclonic jerks, cyanosis, respiratory distress, apneic episodes, sweating, hypothermia, somnolence, hypotonia[en.wikipedia.org]

  • Hyponatremia

    This lady’s urgent admission to hospital was prompted by somnolence following an intentional overdose (7,500 mg) of her sodium valproate medication.[acutecaretesting.org] They include: headache nausea, loss of appetite, vomiting malaise lethargy weakness poor coordination muscle cramps somnolence disorientation personality change Physical Exam[sharinginhealth.ca] The patient was noted to be somnolent and confused. Table 1 summarizes the patient's laboratory data on admission. Table 1.[clinchem.aaccjnls.org]

  • Chronic Kidney Insufficiency

    Chronic kidney insufficiency affects a significant number of individuals in the developed countries, particularly the United States. The progressive nature of the disease and a substantial reduction in the quality of life over the period of time are the primary reasons why an early diagnosis is crucial. Anemia,[…][symptoma.com]

  • Insulinoma

    This is seen in people with diabetes treated with insulin who may show reduction in spontaneous movements and speech, somnolence, poor thinking and work performance, changes[patient.info] […] hypoglycemia in patients with insulinoma. 50-52 With reported mixed effectiveness and a large number of adverse effects (including neurological disorders such as nystagmus, somnolence[hormones.gr]

  • Obstructive Sleep Apnea

    Neither patient exhibited daytime somnolence, although both were subsequently found to have severe obstructive sleep apnea.[ncbi.nlm.nih.gov] We describe a case series of 4 patients with varying degrees of obstructive sleep apnea who incidentally had a history of nocturnal leg cramps.[ncbi.nlm.nih.gov] A 55-year-old woman who presented to the sleep clinic with severe sleep apnea (OSA) (apnea-hypopnea index [AHI] 62) and excessive somnolence (Epworth Sleepiness Scale score[ncbi.nlm.nih.gov]

  • Cinchonism

    Large doses of quinine may lead to severe (but reversible) symptoms of cinchonism: skin rashes, deafness, somnolence, diminished visual acuity or blindness, anaphylactic shock[en.wikipedia.org] Nocturnal leg cramps are a common health problem in the ambulatory setting.[the-medical-dictionary.com] Large doses of quinine may lead to severe symptoms of cinchonism : skin rashes, deafness (reversible), somnolence, diminished visual acuity or blindness, anaphylactic shock[diki.pl]

  • Peripheral Neuropathy

    […] relief. 26 , 27 More recently, two studies have confirmed the efficacy of controlled-release oxycodone. 28 , 29 The side effects of both drugs are predictable and include somnolence[clinical.diabetesjournals.org] The most common adverse events reported in participants taking a gabapentinoid were drowsiness or somnolence, dizziness and nausea (Appendix 6, available at www.cmaj.ca/lookup[doi.org] Withdrawals due to adverse events Specific adverse events, particularly somnolence and dizziness Search methods for identification of studies Electronic searches We searched[doi.org]

  • Nocturnal Myoclonus Syndrome

    Its most common adverse effects include somnolence and dizziness.[merckmanuals.com] Other abnormal movements that may be confused with nocturnal myoclonus are the startles of hyperekplexia, the syndrome of painful legs and moving toes, nocturnal leg cramps[ncbi.nlm.nih.gov] Periodic limb movement disorder (PLMD), is a condition in which a person’s legs or arms twitch, cramp or move involuntarily and periodically during sleep.[nativeremedies.com]

  • Muscle Spasm

    The most common AEs for all groups were dry mouth, constipation, dizziness, headache, and somnolence.[ncbi.nlm.nih.gov] There were 29 patients with nocturnal leg cramps, 28 with cervical spondylosis, 13 with thalamic pain and 11 with carpal tunnel syndrome, for which the effectiveness was assessed[ncbi.nlm.nih.gov] Muscle fatigue and nerve dysfunction are believed to be contribute to nocturnal leg cramps.[onhealth.com]

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