Nocturnal Paroxysmal Dyspnea: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Nocturnal Paroxysmal Dyspnea

Pulmonary Edema

/or comorbid paroxysmal nocturnal dyspnea and orthopnea are present, even in patients with preeclampsia. [ncbi.nlm.nih.gov]

In some patients, extreme edema may result in paroxysmal nocturnal dyspnea, although the pathogenesis of this conditions is not well-understood. [pathwaymedicine.org]

Orthopnea and paroxysmal nocturnal dyspnea are two variants of shortness of breath seen in association with pulmonary edema. [emedicinehealth.com]

High-Output Heart Failure

He denied orthopnea, paroxysmal nocturnal dyspnea, and lower-extremity swelling. He also denied abdominal pain, hematochezia, melena, diarrhea, and flushing. [annals.org]

Attacks of breathlessness severe enough to wake the patient frequently occur during sleep ( paroxysmal nocturnal dyspnea ). [medical-dictionary.thefreedictionary.com]

Symptoms like dyspnea (difficulty in breathing), orthopnea (shortness of breath when lying flat) and paroxysmal nocturnal dyspnea (a severe increase in shortness of breath [ausmed.com]

Mitral Valve Stenosis

(paroxysmal nocturnal dyspnea) and orthopnea, especially when supine Hemoptysis Atrial fibrillation Later stages: signs and symptoms of right-sided heart failure References [amboss.com]

As the stenosis worsens, symptoms of orthopnea, paroxysmal nocturnal dyspnea or dyspnea on exertion develops. [symptoma.com]

As stenosis intensifies Dyspnea may be encountered at rest and may evolve to include orthopnea and paroxysmal nocturnal dyspnea. [pathwaymedicine.org]

Congestive Heart Failure

Features due to left heart failure: Dyspnea, orthopnea and paroxysmal nocturnal dyspnea: These symptoms develop due to congestion of the lungs. [symptoma.com]

Major criteria: · Paroxysmal nocturnal dyspnea · Neck vein distention · Rales · Radiographic cardiomegaly (increasing heart size on chest radiography) · Acute pulmonary edema [medicalcriteria.com]

Later on orthopnea and paroxysmal nocturnal dyspnea also develop. Later on dyspnea occurs even at rest. Orthopnea refers to breathlessness on lying flat. [symptoma.com]

Aortic Valve Insufficiency

Symptoms include exertional dyspnea, orthopnea, paroxysmal nocturnal dyspnea, palpitations, and chest pain. [msdmanuals.com]

As the disease progresses, orthopnea and paroxysmal nocturnal dyspnea start to occur. Angina is predominantly nocturnal in these patients. [symptoma.com]

Chronic AR is typically asymptomatic for years followed by progressive exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. [msdmanuals.com]

Heart Failure

When the legs are elevated at night, the fluid redistributes centrally, causing pulmonary edema that results in orthopnea (dyspnea while laying flat) or paroxysmal nocturnal [healio.com]

dyspnea, or PND. [healio.com]

Mitral Valve Insufficiency

Patients may be asymptomatic or may have manifestations like fatigue caused by reduced cardiac output, tachypnea or dyspnea, orthopnea, paroxysmal nocturnal dyspnea and hemoptysis [symptoma.com]

When the legs are elevated at night, the fluid redistributes centrally, causing pulmonary edema and resulting in orthopnea (dyspnea while lying flat) or paroxysmal nocturnal [healio.com]

急性二尖瓣闭锁不全因未及产生代偿作用，因此会产生较严重的症状，且症状类似郁血性心衰竭，包含呼吸困难、肺水肿（英语：pulmonary edema）、端坐呼吸（英语：orthopnea），以及阵发性夜间呼吸困难（英语：paroxysmal nocturnal dyspnea）等等[3]。 [zh.m.wikipedia.org]

Infiltrative Cardiomyopathy

decreased exercise tolerance, and paroxysmal nocturnal dyspnea. [medbullets.com]

nocturnal dyspnea, and edema. [aafp.org]

Signs and symptoms (orthopnea and paroxysmal nocturnal dyspnea) of left heart failure are also present. [circ.ahajournals.org]

Cardiomyopathy

Symptoms: Patients with cardiomyopathy will typically present with dyspnea, orthopnea, paroxysmal nocturnal dyspnea, bilateral edema, and fatigue. [symptoma.com]

These symptoms of heart failure most commonly include dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and fluid retention. How Is Postpartum Cardiomyopathy Treated? [verywellhealth.com]

nocturnal dyspnea, and edema. [aafp.org]

Ischemic Cardiomyopathy

Pulmonary congestion reduces when the patient is in erect position, it results in improvement in symptoms. [1],[2],[5] Paroxysmal nocturnal dyspnea Paroxysmal nocturnal dyspnea [explainmedicine.com]

nocturnal dyspnea) Chest pain or pressure may be present along with the above symptoms Fatigue and weakness are commonly associated with cardiomyopathy Dizziness and lightheadedness [dovemed.com]

[…] patients in whom the additional volume cannot be pumped out by the left ventricle, there is a significant reduction in vital capacity and pulmonary compliance with resultant dyspnea [explainmedicine.com]

Primary Cardiomyopathy

nocturnal dyspnea, and edema. [aafp.org]

[…] atrial fibrillation (Paf)発作性心房細動 paroxysmal nocturnal dyspnea発作性夜間呼吸困難 paroxysmal supraventricular tachycardia(PSVT)発作性上室性頻拍 paroxysmal ventricular tachycardia (PVT)発作性心室頻拍 [tokyo-med.ac.jp]

Symptoms of heart failure may include shortness of breath, fatigue, cough, orthopnea, paroxysmal nocturnal dyspnea, and edema. [aafp.org]

Secondary Cardiomyopathy

nocturnal dyspnea, and edema. [aafp.org]

Symptoms of heart failure may include shortness of breath, fatigue, cough, orthopnea, paroxysmal nocturnal dyspnea, and edema. [aafp.org]

nocturnal dyspnea, edema ECG shows LVH Echocardiography shows enlarged ventricular chamber, normal or decreased wall thickness, systolic dysfunction Pharmacologic therapy [aafp.org]

Dilated Cardiomyopathy

nocturnal dyspnea (waking up in the middle of the night out of breath) Fatigue, decreased exercise capacity Swelling in the lower limbs (edema) or stomach However, some patients [icm-mhi.org]

The following are the symptoms with which a patient may present: fatigue, orthopnea, dyspnea on exertion, paroxysmal nocturnal dyspnea, increasing edema, weight gain, or an [symptoma.com]

[…] and paroxysmal nocturnal dyspnea[11], angina pectoris[11], and syncope, usually exertional[11]. [en.wikipedia.org]

Aortic Valve Stenosis

The patient also presented dyspnea on minimal exertion, orthopnea, paroxysmal nocturnal dyspnea and edema of lower limbs. The patient denied fever. [web.archive.org]

Other symptoms associated with AS are related to cardiac failure, such as paroxysmal nocturnal dyspnea, orthopnea, and dyspnea on exertion. [symptoma.com]

The clinical picture consists of the SAD triad: syncope upon physical exertion, angina and dyspnea. [symptoma.com]

Myocardial Fibrosis

Additionally, fatigue, paroxysmal nocturnal dyspnea, and orthopnea may be present. Thromboembolic complications may occur in EMF. [emedicine.medscape.com]

With left ventricular involvement, dyspnea is the predominant symptom, especially exertional dyspnea. [emedicine.medscape.com]

Alcoholic Cardiomyopathy

Furthermore, some will have paroxysmal nocturnal dyspnea and episodic coughs that produce frothy sputum. [symptoma.com]

At that point, the symptoms occur due to heart failure and may include: Ankle, feet, and leg swelling Awakening during the night with shortness of breath (paroxysmal nocturnal [flipper.diff.org]

A majority will experience dyspnea on exertion. As ACM progresses, patients can develop orthopnea. [symptoma.com]

Coronary Atherosclerosis

Dyspnea, Orthopnea, and Paroxysmal Nocturnal Dyspnea. Butterworth Publishers. Archived from the original on 27 April 2018. Retrieved 15 August 2014. [en.wikipedia.org]

nocturnal dyspnea.[2] It affects between 1–2% of the general United States population and occurs in 10% of those over 65 years old.[2][13] Risk factors for acute decompensation [en.wikipedia.org]

[…] and efforts to increase blood flow.[2] Congestive heart failure[edit] Congestive heart failure frequently presents with shortness of breath with exertion, orthopnea, and paroxysmal [en.wikipedia.org]

Rheumatic Heart Disease

Children with CHF may also experience shortness of breath on lying flat (orthopnea) or episodes of shortness of breath that wake them from sleep (paroxysmal nocturnal dyspnea [ssa.gov]

[…] consumption酸素消費量 p pacemaker ペースメーカー、歩調取り[細胞] pacemaker potentialペースメーカー電位、歩調取り電位 pacingペーシング palpation 触診［法］ papillary muscle乳頭筋 palpitation動悸、心悸亢進 paradoxical 奇異［性］　【形】 paroxysmal [tokyo-med.ac.jp]

Chagas Disease

nocturnal dyspnea, orthopnea, and jugular venous distension), arrhythmias ( e.g., palpitations, weakness, and syncope), stroke ( e.g., focal neurological deficit secondary [medbullets.com]

[…] sleep (paroxysmal nocturnal dyspnea). [verywellhealth.com]

[…] normal 12-lead electrocardiogram (ECG) determinate form cardiac acute myopericarditis chronic fibrosing myocarditis dilated cardiomyopathy symptoms of heart failure ( e.g., paroxysmal [medbullets.com]

Dilated Cardiomyopathy Type 1NN

The patients present with a wide range of symptoms like dyspnea, orthopnea, paroxysmal nocturnal dyspnea, arrhythmias or complications associated with DCM. [ark.no]

DCM usually presents with any one of the following: (1) Heart failure with symptoms of congestion (edema, orthopnea, paroxysmal nocturnal dyspnea) and/or reduced cardiac output [flybase.org]

Chronic Right-Sided Congestive Heart Failure

Sometimes there is intermittent shortness of breath at night (paroxysmal nocturnal dyspnea). [sharecare.com]

[…] on exertion orthopnea paroxysmal nocturnal dyspnea fatigue pulmonary edema Physical exam cardiovascular exam pitting lower extremity edema jugular venous distention S3 sound [medbullets.com]

[…] and fatigue 1,2 orthopnea: dyspnea in the recumbent position, may use multiple pillows at night 1,2 paroxysmal nocturnal dyspnea: dyspnea that awakens the patient from sleep [radiopaedia.org]

Chronic Pulmonary Edema

In some patients, extreme edema may result in paroxysmal nocturnal dyspnea, although the pathogenesis of this conditions is not well-understood. [pathwaymedicine.org]

Orthopnea and paroxysmal nocturnal dyspnea are two variants of shortness of breath seen in association with pulmonary edema. [emedicinehealth.com]

When edematous fluid is large in volume it can redistribute when an individual lies supine, affecting more lung tissue and thus worsening dyspnea, a phenomenon known as orthopnea [pathwaymedicine.org]

Acute Myocarditis

AIM: Cardiac magnetic resonance (CMR) can visualize inflammatory tissue changes in acute myocarditis. Several quantitative image-derived parameters have been described to enhance the diagnostic value of CMR, but no direct comparison of these techniques is available. METHODS AND RESULTS: A total of 34 patients with[…] [ncbi.nlm.nih.gov]

Toxic Myocarditis

The clinical manifestation and natural history of myocarditis range is variable from asymptomatic stages to intractable circulatory compromise and death. Supportive therapy is paramount in the treatment of this condition. The use of mechanical circulatory support as bridge-to-recovery or bridge-to-transplantation[…] [ncbi.nlm.nih.gov]

Cardiac Asthma

Cardiac asthma is also called paroxysmal nocturnal dyspnea or paroxysmal dyspnea. It is not an asthma in true sense. It is wheezing caused by congestive heart failure. [breath.ygoy.com]

pallor, and anxiety called also paroxysmal dyspnea * * * paroxysmal nocturnal dyspnea that occurs in association with heart disease, such as left ventricular failure. [medicine.academic.ru]

Cardiac asthma is a medical symptom, also known as paroxysmal dyspnea or paroxysmal nocturnal dyspnea ("PND"). [morebooks.de]

Lutembacher Syndrome

Case Reports Case presentation 1 A 53-year-old female was referred to our cardiology clinic with shortness of breath, orthopnea, and paroxysmal nocturnal dyspnea. [go.gale.com]

Signs of pulmonary venous congestion may be seen, such as paroxysmal nocturnal dyspnea, orthopnea, and hemoptysis. [xpertdox.com]

Paroxysmal nocturnal dyspnea, orthopnea, and hemoptysis are signs of pulmonary venous congestion. [checkorphan.org]

Viral Myocarditis

AIMS: Viral myocarditis (VM) is an important cause of heart failure and sudden cardiac death in young healthy adults; it is also an aetiological precursor of dilated cardiomyopathy. We explored the role of the miR-221/-222 family that is up-regulated in VM. METHODS AND RESULTS: Here, we show that microRNA-221[…] [ncbi.nlm.nih.gov]

Acute Aortic Regurgitation

Symptoms include exertional dyspnea, orthopnea, paroxysmal nocturnal dyspnea, palpitations, and chest pain. [merckmanuals.com]

Another reason is the increased demand of oxygen by the hypertrophied left ventricle. [2] Features of Heart Failure (HF) Eg: Paroxysmal nocturnal dyspnea, peripheral edema [explainmedicine.com]

Dyspnea on exertion. 2. Orthopnea - dyspnea when supine. 3. PND - Paroxysmal Nocturnal Dyspnea. Why do you get Nocturnal Angina with Aortic regurgitation? 1. [quizlet.com]

Atrial Myxoma

Clinical Manifestations Symptoms: Due to obstruction of blood flow, valvular regurgitation, impaired contractility Can see dyspnea, orthopnea, paroxysmal nocturnal dyspnea [utswim.wordpress.com]

nocturnal dyspnea, fainting, palpitations, dizziness and syncope, pleuritic chest pain, hemoptysis Diagnosis 2-D, transesophageal echocardiography Management Excision Prognosis [medical-dictionary.thefreedictionary.com]

Symptoms may include: Shortness of breath with activity Platypnea – Difficulty breathing in the upright position with relief in the supine position Paroxysmal nocturnal dyspnea [en.wikipedia.org]

Congenital Mitral Stenosis

( paroxysmal nocturnal dyspnea ) and orthopnea, especially when supine Hemoptysis Atrial fibrillation Later stages: signs and symptoms of right-sided heart failure References [amboss.com]

As stenosis intensifies Dyspnea may be encountered at rest and may evolve to include orthopnea and paroxysmal nocturnal dyspnea. [pathwaymedicine.org]

[…] on exertion, orthopnea, paroxysmal nocturnal dyspnea, and dry cough. [medical-dictionary.thefreedictionary.com]