Nodular Glomerulosclerosis: Causes & Reasons

Possible Causes for Nodular Glomerulosclerosis

These cases were diagnosed as diabetic nodular glomerulosclerosis, although there was no obvious evidence for diabetes. [ncbi.nlm.nih.gov]

A very rare association among smoking, hypertension and nodular mesangial glomerulosclerosis has been recently described. [ncbi.nlm.nih.gov]

Nevertheless, nodular glomerulosclerosis pattern can rarely occur in non-diabetic patients. [ncbi.nlm.nih.gov]

Diabetes Mellitus

Renal glomerulus, nodular glomerulosclerosis, microscopic. Renal glomerulus, nodular glomerulosclerosis, hyaline arteriolosclerosis, PAS stain, microscopic. [library.med.utah.edu]

(later stages): may be diffuse (most common) or pathognomonic nodular glomerulosclerosis (Kimmelstiel-Wilson nodules) Clinical findings Often asymptomatic; ; patients may [amboss.com]

Both nodular and diffuse glomerulosclerosis can lead to chronic renal failure. Diabetics are prone to infections, particularly pyelonephritis. [library.med.utah.edu]

Glomerulosclerosis

Keywords: Nodular glomerulosclerosis, hypertension, obesity, smoking Introduction Nodular glomerulosclerosis is a pathological finding characterized by areas of marked mesangial [ncbi.nlm.nih.gov]

Key -Words: Hypertension; nodular glomerulosclerosis; smoking. [scielo.mec.pt]

(PAS, ob. x40) In nodular diabetic glomerulosclerosis, PAS-positive nodular deposits (containing mucopolysaccharides, fibrils and collagen) may appear in the mesangial space [pathologyatlas.ro]

Light Chain Disease

The differential diagnosis of nodular glomerulosclerosis includes diabetes mellitus, amyloidosis, cryoglobulinaemia and LCDD. [academic.oup.com]

(b) Nodular glomerulosclerosis (c) Nodular glomerulosclerosis (black arrow) and increasing fiber-cell (white arrow). Masson trichrome x 400. (d) PAS-positive nodule. [omicsonline.org]

Nodular glomerulosclerosis (NGS) is the most characteristic; it is found in 60 to 100% of patients with LCDD. [kidneypathology.com]

Nodular Glomerulosclerosis

Idiopathic nodular glomerulosclerosis is an unusual entity with light microscopic and ultrastructural features similar to those of nodular diabetic glomerulosclerosis but [ncbi.nlm.nih.gov]

PubMed Search: Idiopathic nodular glomerulosclerosis Page views in 2021: 430 Page views in 2022 to date: 411 Cite this page: Sangle N. [pathologyoutlines.com]

Morphologically, smoking-associated nodular glomerulosclerosis closely resembles diabetic nephropathy. [ncbi.nlm.nih.gov]

Chronic Nephritic Syndrome with Dense Deposit Disease

A unique coexistence of nodular glomerulosclerosis, as traditionally ascribed to diabetes with a peculiar type of immunotactoid glomerulopathy was confirmed by the exclusion [ncbi.nlm.nih.gov]

Images Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Nodular glomerulosclerosis. [librepathology.org]

IDIOPATHIC NODULAR GLOMERULOSCLEROSIS Idiopathic nodular glomerulosclerosis is a distinct clinicopathologic entity linked to hypertension and smoking. [thedoctorsdoctor.com]

Fibronectin Glomerulopathy

Key -Words: Hypertension; nodular glomerulosclerosis; smoking. [scielo.mec.pt]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria Osmotic Diuresis [thekaiganfoundation.com]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Focal Embolic Glomerulonephritis

Images Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Nodular glomerulosclerosis. [librepathology.org]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Smoking-related moderate nodular glomerulosclerosis, (associated with longstanding smoking and COPD), focal subcapsular cortical scar with ischemic glomerulosclerosis, consistent [dovepress.com]

Disorders of Amino-Acid Transport

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria Osmotic Diuresis [thekaiganfoundation.com]

glomerulosclerosis or, rarely, glomerulonephritis) Cast nephropathy Amyloidosis The isoelectric point (pI) of the light chain may be an important determinant of its potential [emedicine.medscape.com]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Autosomal Dominant Progressive Nephropathy with Hypertension

glomerulosclerosis, microscopic Nodular glomerulosclerosis and hyaline arteriolosclerosis, microscopic, PAS stain Diffuse glomerulosclerosis, microscopic, PAS stain End stage [library.med.utah.edu]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria Osmotic Diuresis [thekaiganfoundation.com]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Alpha-Heavy Chain Disease

Nodular glomerulosclerosis, however, is infrequent ( 2 ). [cjasn.asnjournals.org]

In Panel A a light-microscopical section stained with Masson's trichrome shows nodular glomerulosclerosis with enlarged glomerular-capillary tuft (x410). [nejm.org]

Internal Medicine, 49, 1411-1415. http://dx.doi.org/10.2169/internalmedicine.49.3499 [ 15 ] Moulin, B., et al. (1999) Nodular Glomerulosclerosis with Deposition of Monoclonal [scirp.org]

Non-Allergic Interstitial Nephritis

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria Osmotic Diuresis [thekaiganfoundation.com]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

[…] and Glomerulopathy Nail-patella Syndrome Nephrocalcinosis Nephrogenic Systemic Fibrosis Nephroptosis (Floating Kidney, Renal Ptosis) Nephrotic Syndrome Neurogenic Bladder Nodular [thekaiganfoundation.com]

Heavy Chain Disease

Nodular glomerulosclerosis, however, is infrequent ( 2 ). [cjasn.asnjournals.org]

In Panel A a light-microscopical section stained with Masson's trichrome shows nodular glomerulosclerosis with enlarged glomerular-capillary tuft (x410). [nejm.org]

Internal Medicine, 49, 1411-1415. http://dx.doi.org/10.2169/internalmedicine.49.3499 [ 15 ] Moulin, B., et al. (1999) Nodular Glomerulosclerosis with Deposition of Monoclonal [scirp.org]

Proliferative Glomerulonephritis

[…] account the aforementioned diseases, and especially Randall type MIDD (heavy/light chain deposition type). 5 In this disease, the most typical glomerular involvement is nodular [revistanefrologia.com]

[…] diag Benign nephrosclerosis Papillary necrosis Pyelonephritis with infarction Nodular glomerulosclerosis Renal abscesses 95. 14y Male, severe acute renal failure, history [de.slideshare.net]

glomerulosclerosis, although membranoproliferative GN can also be observed, tubular deposits are practically a constant, and the electron microscope findings would be different [revistanefrologia.com]

Hyporeninemic Hypoaldosteronism

Renal biopsy revealed nodular glomerulosclerosis associated with the accumulation of kappa light chains. Isolated microscopic hematuria was present for over 1 year. [ncbi.nlm.nih.gov]

Autosomal Dominant Mental Retardation Type 3

It is also known as “focal glomerular sclerosis” or “focal nodular glomerulosclerosis.” [checkrare.com]

Serpentine Fibula - Polycystic Kidneys Syndrome

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria Osmotic Diuresis [thekaiganfoundation.com]

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Gamma-Heavy Chain Disease

Nodular glomerulosclerosis, however, is infrequent ( 2 ). [cjasn.asnjournals.org]

In Panel A a light-microscopical section stained with Masson's trichrome shows nodular glomerulosclerosis with enlarged glomerular-capillary tuft (x410). [nejm.org]

In patients with HCDD, immunofluorescence with anti-LC antibodies is negative despite typical nodular glomerulosclerosis. [cjasn.asnjournals.org]

Renal Fibroma

Basement membrane thickening Nodular glomerulosclerosis Capsular drop Fibrin cap ANSWER 20-2. [web.duke.edu]

The resected kidney was somewhat nodular and measured 7.0 × 4.0 × 1.5 cm. [archivesofpathology.org]

Chronic glomerulonephritis Chronic pyelonephritis Arteriolonephrosclerosis Nodular glomerulosclerosis Analgesic nephropathy ANSWER 12-2. [web.duke.edu]

Immunoglobulin-Mediated Membranoproliferative Gomerulonephritis

Images Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Nodular glomerulosclerosis. [librepathology.org]

Idiopathic nodular glomerulosclerosis General Not diabetic - key feature. [librepathology.org]

DDx Image Nodular glomerulosclerosis nodular mesangial matrix expansion GBM thickening, both afferent and efferent arteriole hyalinized EM? [librepathology.org]

Immunoglobulin Heavy Chain Deficiency

Key renal biopsy findings include extensive extracellular matrix deposition with nodular glomerulosclerosis. [alliedacademies.org]

Glomerular mesangial matrix expansion with nodular glomerlosclerosis may resemble diabetic glomerulosclerosis, but is different because of the relatively regular nodular distribution [alliedacademies.org]

Renal pathology includes mesangial matrix expansion, hypercellularity, and nodular sclerosis resembling diabetic glomerulosclerosis. [alliedacademies.org]

Autoimmune Hemolytic Anemia

A renal biopsy was performed and demonstrated nodular glomerulosclerosis with no evidence of immune complex deposition. [dx.doi.org]

Concomitant features of liver dysfunction and nephrotic syndrome secondary to nodular glomerulosclerosis were also seen. [dx.doi.org]

On the basis of the findings of light and electron microscopy and immunopathology, a diagnosis of nodular glomerulosclerosis with no evidence of immune complex deposition [dx.doi.org]

Calcific Pancreatitis

Abstract Nodular (specific) intercapillary glomerulosclerosis (Kimmelstiel-Wilson) was found at autopsy in a 47-year-old man who had been diabetic for 20 years. [diabetes.diabetesjournals.org]

This is only the fourth recorded case of histologically documented nodular glomerulosclerosis occurring in a patient with pancreatogenic diabetes. [diabetes.diabetesjournals.org]

Familial Interstitial Nephritis

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Fibrosis Nephronophthisis due to Nephrocystin-1 Gene Deletions Nephroptosis (Floating Kidney, Renal Ptosis) Nephrotic Syndrome Neurogenic Bladder 9/11 and Kidney Disease Nodular [kidney.nyc]

Congenital Renal Failure

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Fibrosis Nephronophthisis due to Nephrocystin-1 Gene Deletions Nephroptosis (Floating Kidney, Renal Ptosis) Nephrotic Syndrome Neurogenic Bladder 9/11 and Kidney Disease Nodular [kidney.nyc]

Familial Juvenile Hyperuricemic Nephropathy Type 1

Glomerulosclerosis Non-Gonococcal Urethritis Nutcracker syndrome Oligomeganephronia Orofaciodigital Syndrome Orotic Aciduria Orthostatic Hypotension Orthostatic Proteinuria [kidney.nyc]

Fibrosis Nephronophthisis due to Nephrocystin-1 Gene Deletions Nephroptosis (Floating Kidney, Renal Ptosis) Nephrotic Syndrome Neurogenic Bladder 9/11 and Kidney Disease Nodular [kidney.nyc]

Sagliker Syndrome

Crescentic nodular glomerulosclerosis secondary to truncated immunoglobulin heavy chain deposition. [cambridge.org]

Idiopathic nodular glomerulosclerosis is a distinct clinicopathologic entity linked to hypertension and smoking. [cambridge.org]

Gamma-heavy chain deposition disease showing nodular glomerulosclerosis. Clin Nephrol 1995; 44:394–9.Google ScholarPubMed Herrera, GA, Turbat-Herrera, EA. [cambridge.org]

Nesidioblastosis

We therefore hypothesize that our patient might have had an undiagnosed DM in the past, which resulted in the typical diabetic nodular glomerulosclerosis. [ncbi.nlm.nih.gov]

To our surprise, the renal pathology disclosed typical diabetic nodular glomerulosclerosis in the same patient who had no previous history of diabetes mellitus (DM). [ncbi.nlm.nih.gov]

Renal Glomerular Disease

Nodular glomerulosclerosis B. Hyperplastic arteriolosclerosis C. Papillary necrosis D. Crescentic glomerulonephritis E. Pyelonephritis A. [quizlet.com]

Nodular glomerulosclerosis, the hallmark of diabetic glomerulopathy, can result from conditions as disparate as chronic thrombotic microangiopathy and cigarette smoking [ [karger.com]

The arteriole at the vascular pole of the glomerulus is also involvedAmyloidosis Note globally sclerotic glomeruli and extensive tubular atrophy and nodular intraglomerular [memorize.com]

Bangstad Syndrome

Images Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Diabetic glomerulosclerosis. (WC/KGH) Nodular glomerulosclerosis. [librepathology.org]

Diabetic glomerulosclerosis, with nodular pattern (1). Arteriolar hyalinosis (2). ii ) Methenamine silver 20 X. Diffuse and nodular glomerulosclerosis. [soc-bdr.org]

Idiopathic nodular glomerulosclerosis General Not diabetic - key feature. [librepathology.org]