Nodular Lesions: Causes & Reasons

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Possible Causes for Nodular Lesions

Epidermolysis Bullosa Pruriginosa

and nodular prurigolike lesions Intense pruritus has been reported to accompany or predate the cutaneous manifestations by several years. [interactivederma.com]

Epidermolysis bullosa pruriginosa, a genetic mechanobullous disease, is characterized by pruritus, lichenified or nodular prurigo-like lesions, occasional trauma-induced blistering [ncbi.nlm.nih.gov]

It is characterized by extremely pruritic, lichenified or nodular lesions predominantly over legs, milia formation and albopapuloid lesions on the trunk. [e-ijd.org]

Endemic Kaposi Sarcoma

We herein discuss the unusual presentation of a 53-year-old indigenous patient with purplish-brown nodular lesions on lower extremities, and miliary tuberculosis. [ajtmh.org]

On the other hand, patients with AIDS-associated KS have early lesions (patch and plaque) compared to classical KS patients (predominantly nodular lesions). [bjournal.org]

lesions; (b) 30- 40% of the CD34+ SC were LANA- in both early and late KS, suggesting a continuous recruitment of noninfected endothelial cell into the KS lesion; (c) LANA [openarchive.ki.se]

Tenosynovitis

These areas were filled by fluid and multiple small nodular lesions. [ncbi.nlm.nih.gov]

There was no effusion or a space occupying lesion within the joint. [faoj.org]

The mass had neat contours, consisted of numerous, small nodular regions and had no connection with the tibiotalar joint. [faoj.org]

Leprosy

Marjolin's ulcer consists of the malignant transformation of a chronic ulcerative lesion. [ncbi.nlm.nih.gov]

This report describes a case of HL in a 14-year-old Brazilian boy, who presented with multiple nodular and tumor-like lesions, simulating keloids. [ncbi.nlm.nih.gov]

An 83-year-old woman presented with papular, nodular and tumor-like lesions of 3 years of evolution, affecting fingers, toes, hands, thighs and knees, and wide superficial [ncbi.nlm.nih.gov]

Blastomycosis

Cases have been misidentified as keratoacanthoma, pyoderma gangrenosum, carcinoma, or as Weber-Christian panniculitis if there are nodular subcutaneous lesions. [ncbi.nlm.nih.gov]

mass like lesions, interstitial disease, cavitation (37% 8 ) and military disease 6-7. [radiopaedia.org]

A chest radiograph showed bilateral diffuse nodular infiltrates and cavitary lung lesions. [doi.org]

Merkel Cell Carcinoma

Subcutaneous nodular lesion with overlying erythema was the most common finding (72.7%, 8/11). [kiss.kstudy.com]

On examination, a 15 millimeter (mm) nodular skin lesion was found with a surrounding area of psoriasis. [imj.ie]

Violaceous, lobulated, polypoid cutaneous nodule Gross description Fleshy to tan-brown lesion with nodular or ill defined silhouette Variable ulceration Gross images Contributed [pathologyoutlines.com]

Nodular Malignant Melanoma

hypopigmented or achromic nodular lesion. [clinicaldermatology.eu]

Nodular melanoma often presents as an expanding darkly pigmented cutaneous nodular lesion, usually found on the sun-exposed areas of the skin, with far fewer such lesions [ncbi.nlm.nih.gov]

To the Editor: An 81-year-old man presented with a nodular polypoid lesion that developed on a flat lesion on the back of 2 years’ duration. [mdedge.com]

Hepatic Nodular Hyperplasia

During pre-transplantation evaluation, CT and MRI revealed a large hepatic lesion with multiple small nodular lesions. [ncbi.nlm.nih.gov]

[…] vascularity Focal nodular hyperplasia: Incidentaly found liver lesion that proved to be a focal nodular hyperplasia Focal nodular hyperplasia: Focal nodular hyperplasia with [ultrasoundcases.info]

• Lyon South Hospital, Hospices Civils de Lyon • France In a 45-year-old woman recently operated for a breast cancer, ultrasound revealed a right hepatic nodular lesion. [clinical.netforum.healthcare.philips.com]

Focal Nodular Hyperplasia

Described herein is the case of an 8-year-old boy who developed a hepatic nodular lesion after having received anti-neoplastic therapy for nephroblastoma. [ncbi.nlm.nih.gov]

In a 49 year old male, a chronic alcoholic with hepatomegaly, a subcapsular nodular lesion was detected in the right lobe of the liver. [ncbi.nlm.nih.gov]

This report describes the case of a 31-year old female patient developing multiple focal nodular hyperplasia (FNH) lesions two years after portocaval shunting and extended [ncbi.nlm.nih.gov]

Pulmonary Lymphomatoid Granulomatosis

There are no specific presumptive clinical and laboratory findings, including tumor markers and imaging techniques, that distinguish LG from other pulmonary nodular lesions [ncbi.nlm.nih.gov]

A chest radiograph showed multifocal patchy consolidations with nodular lesions. [ncbi.nlm.nih.gov]

LYG is considered an Epstein-Barr virus-driven lymphoproliferative disorder that often presents with multiple nodular lesions in the lungs and sometimes involvement of skin [casereports.bmj.com]

Erythema Elevatum Diutinum

We describe a 16-year-old boy who presented with symmetrical nodular lesions accompanied by vesicles on the dorsa of his hands. Biopsy findings were consistent with EED. [ncbi.nlm.nih.gov]

We studied a 64-year-old man with decreased visual acuity and nodular lesions in both hands. [ncbi.nlm.nih.gov]

LeBoit PE, Cockerell CJ: Nodular lesions of erythema elevatum diutinum in patients infected with the human immunodeficiency virus. [accessmedicine.mhmedical.com]

Familial Cardiac Lipidosis

Grossly, the affected heart usually shows small, multifocal, subendocardial or myocardial yellow-tan nodular lesions or poorly defined plaques. [ncbi.nlm.nih.gov]

Lymphomatoid Granulomatosis

Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic [ncbi.nlm.nih.gov]

Abstract Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of [doi.org]

We report a 15-year-old boy presented with fever, dry cough and dyspnea from two months ago, after admission patient had nodular lesions on the left leg and hepatosplenomegaly [ncbi.nlm.nih.gov]

Nodular Localized Cutaneous Amyloidosis

Primary localized cutaneous nodular amyloidosis with bullous lesions. [ijdvl.com]

Dermatological examination revealed many skin colored nodular lesions both on dorsal and ventral side of corpus penis. [turkiyeklinikleri.com]

Other terms that describe the various lesions of nodular localized cutaneous amyloidosis include waxy, purpuric, yellowish, or bullous. Lesions tend not to ulcerate. [dermaamin.com]

Cutaneous Metastasis in Breast Cancer

Chest X-ray and TC-study showed multiple nodular lesions involving both lungs. [casesjournal.biomedcentral.com]

Though there have been several reports of CM in breast cancer, diffuse CM scattered all over the body with nodular lesion on both eyelids is very rare. [ccij-online.org]

The skin lesion was single in 4 cases and multiple in 8 cases. They appear as erythematous and nodular painless lesions in most cases. [omicsonline.org]

Nodular Glomerulosclerosis

Nodular lesions also showed a marked increase in number of glomerular CD68-positive macrophages. [ncbi.nlm.nih.gov]

A renal biopsy showed typical nodular lesions (Kimmelstiel-Wilson's lesions). Previously, the interesting feature of transient proteinuria had been recognized. [ncbi.nlm.nih.gov]

Glomerular nodular lesions, thus, can occur in heavy chain deposition disease, as in light chain deposition disease. [ncbi.nlm.nih.gov]

Syringocystadenoma Papilliferum

The nodular lesion was excised, and the lower eyelid was reconstructed with V-Y advancement flap. [ncbi.nlm.nih.gov]

This showed a nodular lesion 0.7 cm in its greatest axis 0.3 cm away from the nearest peripheral surgical cut margins. [ijo.in]

Intraoperative picture showing ulcerated, nodular lesion on the vertex Marking for wide local excision and bilobed flap reconstruction Post-surgery and reconstruction Photomicrograph [ncbi.nlm.nih.gov]

Pigmented Villonodular Synovitis

PVNS rarely forms an osteolytic lesion in a bone. Here we report a unique case of PVNS with a nodular lesion in the left patella. [ncbi.nlm.nih.gov]

Histology revealed a nodular lesion of stromal cells and numerous giant cells with villous architecture as well as abundant haemosiderin deposition with foamy macrophages [ncbi.nlm.nih.gov]

Localized PVNS is an unusual presentation of the disease, generally consisting of a nodular lesion protruding into the articular cavity. [ncbi.nlm.nih.gov]

Mycobacterium Marinum Skin Granuloma

Infections in human consist of nodular cutaneous lesions that can progress to tenosynovitis, arthritis, and osteomyelitis. [ncbi.nlm.nih.gov]

Infections in human consist of nodular cutaneous lesions that can progress to tenosynovitis, arthritis, and osteomyelitis ( 4 ). [ncbi.nlm.nih.gov]

Nodular lesions developed in a linear pattern that extended to the antecubital fossa (B and C). [mdedge.com]

Erythema Induratum

Both skin nodular lesions and lymph nodes responded positively to antituberculous therapy. [ncbi.nlm.nih.gov]

Two female patients with a long history of recurrent erythematous nodular lesions of the lower limbs came to our observation; in both cases, the correlation between the clinical [moh-it.pure.elsevier.com]

Erythema induratum (EI) was originally described by Ernest Bazin in 1861 as nodular lesions on the legs in association with tuberculosis (TB). [ncbi.nlm.nih.gov]

Chromoblastomycosis

Chromoblastomycosis is a chronic, subcutaneous mycosis, characterized by verrucous nodular lesions, usually involving the legs and mainly caused by Fonsecaea, Phialophora, [ncbi.nlm.nih.gov]

Verrucous and nodular lesions are the common clinical presentation. [jmedsoc.org]

Our patient, a 65-year-old healthy man living in Rio de Janeiro had a verrucous plaque, surmounted by multiple papular nodular lesions extending from the knee to the root [jaad.org]

Disseminated Sporotrichosis

lesions of the cutaneous and subcutaneous tissues. [icd9data.com]

Forms of Sporotrichosis Sporotrichosis has 3 forms: Cutaneous lymphatic sporotrichosis Red, nodular lesions of the skin, along with secondary lesions of the lymphatic vessels [healthinplainenglish.com]

This chronic disorder manifests with swelling anddeformity of the involved area as well as the development of nodular lesions withfistulas secreting a viscous seropurulent [dokumen.tips]

Pulmonary Sporotrichosis

lesions of the cutaneous and subcutaneous tissues. [icd9data.com]

Sporotrichosis ( C0038034 ) Definition (MSH) The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues [fpnotebook.com]

Diagnosis History and Symptoms Symptoms of cutaneous sporotrichosis include nodular lesions on the skin, at the point of inoculation, as well as along lymph nodes and vessels [wikidoc.org]

Atypical Measles

Roentgenographic studies showed diffuse, segmental, and nodular chest lesions. Hypoxemia (mean arterial Po2, 58 mm Hg) and markedly reduced lung volumes were noted. [ncbi.nlm.nih.gov]

Atypical measles pneumonia should be considered an explanation for nodular pulmonary lesions in older children and young adults. [ncbi.nlm.nih.gov]

Resolution and shrinkage of the pneumonic infiltrates into nodular mass-like lesions have been cited only once before. [ncbi.nlm.nih.gov]

Cutaneous Atypical Mycobacterial Infection

A case of cutaneous atypical mycobacterial infection due to Mycobacterium fortuitum is described, with neither ulcerative nor purulent nodular lesions and plaques on the legs [moh-it.pure.elsevier.com]

The patient had 3 nodular lesions arranged in a linear fashion on the extensor aspect of the right forearm since about 1 month. [ijdvl.com]

After treatment with oral minocycline (200mg/day) for 9 weeks followed by sparfloxacin (200mg/day) for 5 weeks, the nodular lesions cured with atrophic scars. [ci.nii.ac.jp]

Systemic Bartonellosis

Nodular lesions (forma nodular) are larger but fewer and may be more prominent on the extensor surfaces of the arms and legs. [histopathology-india.net]

At the time, the miliary warts had disappeared, including the penile lesion, and the size of the nodular lesions had decreased by approximately 50%. [doi.org]

At times, a few large, deep-seated lesions, which tend to ulcerate, develop near joints and limit motion. [histopathology-india.net]

Kaposi Sarcoma of the Lung

Histologic examination of the lung from patients whose radiographs showed predominantly nodular lesions revealed a prevalence of nodules composed of prominent spindle cells [ncbi.nlm.nih.gov]

Presentation [ 1, 3 ] Skin lesions may be nodular, papular or blotchy; they may be red, purple, brown or black. [patient.info]

Nodular lesions are of varying size and thickness. They are purple and will at times have a halo of brown or yellow pigment around them. [healthcentral.com]

Hepatic Sarcoidosis

We present this case for two reasons: (1) hepatic sarcoidosis was associated with chronic active hepatitis C; (2) hepatic nodular lesions were evaluated by CT throughout the [ncbi.nlm.nih.gov]

About half of patients had abnormal imaging study with hypodense nodular lesions being the most common abnormality (six patients) followed by hepatomegaly (three patients) [ncbi.nlm.nih.gov]

lesions. [mdedge.com]

Majocchi's Granuloma

A 48-year-old female patient who had undergone liver transplantation nine months earlier, presented with red papules and nodular lesions on her back, buttock and thigh of [ncbi.nlm.nih.gov]

lesions were reported in 65.3% of MG cases in healthy individuals, 58.1% of which were nodular lesions that were not associated with papular lesions. [doi.org]

Nodular lesions were detected in 53.3% and 65.3% of cases in immunosuppressed hosts and healthy individuals, respectively. [doi.org]

Gastric Syphilis

A review of the recent reports indicated that most cases of early phase gastric syphilis seem to present morphologically either as a narrowing lesion or shallow ulcero-nodular [ncbi.nlm.nih.gov]

A follow‑up CT‑scan one year later did not show any remaining hepatic nodular lesions (Fig. 3). [scielo.mec.pt]

Gastroendoscopy revealed an oedematous and hyperaemic mucosa with multiple muco-purulent erosions and nodular lesions from the mid-body into the antrum ( Figure 2 ). [em-consulte.com]