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47 Possible Causes for Normal Cognition and Intellectual Function

  • Infantile-Onset Ascending Hereditary Spastic Paralysis

    Infantile-onset ascending hereditary spastic paralysis (IAHSP) is a rare, early-onset autosomal recessive motor neuron disease associated with mutations in ALS2. We studied a 17-year-old boy who had features of IAHSP. We also reviewed the current literature on ALS2-related syndromes. Clinical and neuroimaging[…][ncbi.nlm.nih.gov]

  • Alzheimer Disease

    AAMI Age‐associated memory impairment Subjective and objective memory loss associated with normal aging; individual aged 50 and older and shows adequate intellectual function[doi.org] MD Minimal dementia Cognitive impairment in memory and minor and variable errors in orientation; no evidence of impaired occupational or social functioning; self care unimpaired[doi.org]

  • Alcohol Dementia

    […] deficit of sufficient severity to affect a participant's activities of daily living, and history of normal intellectual function before the onset of cognitive abnormalities[jamanetwork.com] 31 Neurologists completed the Unified Parkinson's Disease Rating Scale, 36 and the Hachinski Ischemic Scale. 37 They diagnosed dementia based on a progressive or static cognitive[jamanetwork.com]

  • Unverricht-Lundborg Syndrome

    The progression of the disease is slow and patients usually maintain normal cognitive functioning for a long time with slow intellectual decline spanning 10 – 20 years.[epilepsy.com]

  • Autistic Disorder

    People with normal intelligence/adaptive functioning and milder autistic symptoms generally have the best outcomes, those with MR or intellectual disability and severe autistic[web.archive.org] Adult outcomes seem to correlate better with level of cognitive-adaptive functioning than with the severity of autistic symptoms.[web.archive.org] […] symptoms have the worst outcomes within the continuum, and those with normal cognitive-adaptive skills and severe autistic symptoms generally do better than those with MR[web.archive.org]

  • Dialysis Dementia

    Test results showed that 15% of the subjects had cognitive impairment, a condition in which memory or other cognitive domains are below normal without interfering with daily[kidney.org] Mild cognitive impairment is considered to be a transitional phase between normal cognitive function and dementia.[kidney.org] functioning.[kidney.org]

  • Myoclonic-Astatic Epilepsy

    With regard to cognitive function and intelligence outcome, 26-80% of MAE patients were reported to be intellectually normal, with others having mildly to moderately impaired[omicsonline.org] Several past studies on cognitive function in MAE described incidences of intellectual impairment, with normal level intelligence present in 26% [ 1 ], 59% [ 2 ], and 80%[omicsonline.org] However, little is known about the behavioral problems in MAE and the relationships between the symptoms of epilepsy, cognitive function, and behavior.[omicsonline.org]

  • Neurogenic Arthrogryposis Multiplex Congenita

    Cognition: typically normal. 25% of individuals have intellectual disability/CNS involvement. 4 Functional assessment Functional history should include: Developmental milestones[now.aapmr.org]

  • Arthrogryposis due to Muscular Dystrophy

    Cognition: typically normal. 25% of individuals have intellectual disability/CNS involvement. 4 Functional assessment Functional history should include: Developmental milestones[now.aapmr.org]

  • Mucopolysaccharidosis

    Normal intellectual function has been reported in males with mild MPS II but few studies are available that provide comprehensive cognitive profiles.[ncbi.nlm.nih.gov]

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