Normal Intellectual Development: Causes & Reasons

Possible Causes for Normal Intellectual Development

Hemimegalencephaly and normal intellectual development. [jnnp.bmj.com]

Most children with hemimegalencephaly have some level of intellectual disability. Some can attain near normal intellectual development if seizures are controlled. [brainrecoveryproject.org]

Dandy-Walker Syndrome

Prognosis The effect of Dandy-Walker Syndrome on intellectual development is variable, with some children having normal cognition and others never achieving normal intellectual [ninds.nih.gov]

intellectual development is poor [11], This study addresses the outcome of children with the DWS diagnosed at the Johns Hopkins Hospital from 1966 to 1983. [jhu.pure.elsevier.com]

[…] having normal cognition and others never achieving normal intellectual development even when the excess fluid buildup is treated early and correctly. [ninds.nih.gov]

Phocomelia Type Schinzel

$config[ads_text] not found These patients have normal growth and intellectual development. Inbreeding may be involved. [eng.how10.com]

Verloes-Deprez Syndrome

Intellectual development is normal. The syndrome is most likely inherited in an autosomal recessive manner. [orpha.net]

Benign Familial Neonatal Epilepsy Type 2

However, some affected individuals develop intellectual disability that becomes noticeable in early childhood. [medlineplus.gov]

Typically, seizures are the only symptom of BFNS, and most people with this condition develop normally. [medlineplus.gov]

By age 2, most affected individuals who had EEG abnormalities have a normal EEG reading. [medlineplus.gov]

Congenital Disorder of Glycosylation Type 1L

Although most children have some form of intellectual disability, children have been reported with normal intellectual development or only extremely mild deficiencies. [rarediseases.org]

Some of these individuals have normal intellectual development. Therefore, the complete clinical spectrum of PMM2-CDG is still being defined. [rarediseases.org]

Language and motor development can be affected and significantly delayed. Most affected children do not develop normal speech patterns. [rarediseases.org]

Bamforth Syndrome

Intellectual development is normal if treatment for hypothyroidism is not delayed. Last updated: 6/1/2019 [rarediseases.info.nih.gov]

Prognosis With proper treatment adherence the prognosis is good and children can have normal physical growth, pubertal development, and anterior pituitary function. [rarediseases.info.nih.gov]

Pfeiffer Syndrome Type 3

intellectual development. [verywellhealth.com]

[…] neurological and intellectual development, generally has good outcome and can be found dominantly inherited. [scielo.br]

It is associated with normal neurological and intellectual development, and generally has a good outcome. [ojrd.biomedcentral.com]

Familial Capillaro-Venous Leptomeningeal Angiomatosis

Child Neuropsychology : A Journal on Normal and Abnormal Development in Childhood and Adolescence, 22(6), 635-648. [ Links ] Balkuv E, Isik N, Canturk IA, Isik N, Basaran [scielo.senescyt.gob.ec]

[Formula: see text]Intellectual and adaptive functioning in Sturge-Weber Syndrome. [scielo.senescyt.gob.ec]

Monogenic Diabetes

intellectual development is usually good.[3] Individuals seeking prognosis information for themselves or family members should speak with their health care professional. [rarediseases.info.nih.gov]

[…] prognosis may be better determined with knowledge of the underlying genetic cause of the disease.[5] With proper management, the overall prognosis for general health and normal [rarediseases.info.nih.gov]

Maple Syrup Urine Disease Mild Variant

Early diagnosis and dietary intervention prevent complications and may allow for normal intellectual development. [emedicine.medscape.com]

Initially, these children will be asymptomatic and thus show normal early development with normal intellectual levels. [maplesyrupstory.blogspot.com]

Intermittent MSUD [ 2 ] Affected children have normal growth and intellectual development throughout infancy and early childhood. [patient.info]

Synostosis

development. [manipal.pure.elsevier.com]

Our case highlights the difficulty in establishing a clinical diagnosis in individuals with minor clinical features of Roberts syndrome and normal intellectual and social [manipal.pure.elsevier.com]

Congenital Disorder of Glycosylation Type 2I

Although most children have some form of intellectual disability, children have been reported with normal intellectual development or only extremely mild deficiencies. [rarediseases.org]

Some of these individuals have normal intellectual development. Therefore, the complete clinical spectrum of PMM2-CDG is still being defined. [rarediseases.org]

Language and motor development can be affected and significantly delayed. Most affected children do not develop normal speech patterns. [rarediseases.org]

Humeroradial Synostosis with Craniofacial Anomalies

development. [manipal.pure.elsevier.com]

Affected individuals typically have mild intellectual disability, but may have normal development (summary by Reynolds et al., 2017). [203.71.232.25]

Intermittent Maple Syrup Urine Disease

Prior to the first episode, these patients have normal physical and intellectual development. Thiamine-responsive is the rarest sub-type. [thinkgenetic.com]

Clinical description Unlike classic MSUD (see this term), patients with intermittent MSUD show normal growth and intellectual development during infancy and childhood. [orpha.net]

Intermittent MSUD [ 2 ] Affected children have normal growth and intellectual development throughout infancy and early childhood. [patient.info]

Nijmegen Breakage Syndrome

intellectual development: the Nijmegen breakage syndrome. [link.springer.com]

Intellectual development is normal in most people with this condition for the first year or two of life, but then development becomes delayed. [medlineplus.gov]

borderline intellectual ability. [endocrine-abstracts.org]

Congenital Hypothyroidism without Goiter

[…] brain affecting normal brain development resulting in intellectual disability and problems with movement. [informatics.jax.org]

[…] brain affecting normal brain development resulting in intellectual disability and problems with movement. ( 2 ) References: GARD:5617 MESH:C537047 OMIM:300523 Ontology: Human [zfin.org]

[…] brain affecting normal brain development resulting in intellectual disability and problems with movement. ( Human Disease Ontology, DOID_0050631 ) Similar Terms Downloads [amp.pharm.mssm.edu]

ARID1b-Related Disorder

In the latter case, prenatal counselling is based on statistical data showing that ∼70% of children born after the identification of isolated ACC have a normal intellectual [academic.oup.com]

These changes likely affect the control of gene expression and interfere with normal brain development, but the specific relationship between the mutations and ASD is unknown [encyclopedia.pub]

It is unclear why some people with an ARID1B gene variant develop intellectual disability and others have the additional features of Coffin-Siris syndrome. [medlineplus.gov]

Arthrogryposis due to Muscular Dystrophy

intellectual development ( Williams, 1978 ). [mhmedical.com]

There is normal intellectual development in most cases. [clinicalgate.com]

Normal intellectual development in most cases. [orthopaedicsone.com]

Classic Maple Syrup Urine Disease

Prior to the first episode, these patients have normal physical and intellectual development. Thiamine-responsive is the rarest sub-type. [thinkgenetic.com]

Intermittent MSUD [ 2 ] Affected children have normal growth and intellectual development throughout infancy and early childhood. [patient.info]

Benefits The benefits of strict adherence to the MSUD diet are normal physical and intellectual development and a normal life span with no limitations on activity. [diet.com]

Diencephalic Syndrome

[…] caloric intake, normal linear growth, normal intellectual development, abnormal eye movement such as nystagmus and sometimes blindness which may be from optic atrophy. [akidsbraintumorcure.org]

The diencephalic syndrome includes clinical characteristics of severe emaciation, normal linear growth, and normal or precocious intellectual development in association with [ncbi.nlm.nih.gov]

[…] of 11 patients treated at Dana-Farber Cancer Institute, the median age at diagnosis was 18 months (range 4-56 months) Symptoms/Characteristics: severe emaciation despite normal [akidsbraintumorcure.org]

Emanuel Syndrome

The excess genetic material disrupts the normal course of development, leading to intellectual disability and birth defects. [en.wikipedia.org]

Mucopolysaccharidosis Type 2

intellectual development. [pediatrics.aappublications.org]

[…] intelligence is impaired, and death usually occurs in the second decade of life, whereas those patients with minimal or no neurologic involvement may survive into adulthood with normal [pediatrics.aappublications.org]

Xia-Gibbs Syndrome

Researchers suspect that a reduction in the amount of functional AHDC1 protein impairs normal brain development, leading to intellectual disability, speech problems, and other [encyclopedia.pub]

Or, the abnormal proteins may interfere with the function of AHDC1 proteins produced from the normal copy of the gene. [encyclopedia.pub]

Generalized Amyoplasia

intellectual development ( Williams, 1978 ). [mhmedical.com]

[…] absent and there is an increase in the amount of subcutaneous fat), presence of deep skin dimples in the vicinity of affected joints, absence or fibrosis of muscles, and normal [mhmedical.com]

Mucopolysaccharidosis Type 6

intellectual development but share many of the physical symptoms found in Hurler syndrome. [en.wikipedia.org]

MPS VI[edit] Children with MPS VI, Maroteaux–Lamy syndrome, usually have normal intellectual development but share many of the physical symptoms found in Hurler syndrome. [en.wikipedia.org]

Maroteaux (1926–) and his mentor Maurice Emil Joseph Lamy (1895–1975), both French physicians. [3] [4] Symptoms [ edit ] Children with Maroteaux–Lamy syndrome usually have normal [en.wikipedia.org]

Maple Syrup Urine Disease

Early diagnosis and dietary intervention prevent complications and may allow for normal intellectual development. [emedicine.medscape.com]

Trisomy 20

Regular assessments up to the age of 6.5 years revealed normal physical and intellectual development in both children. [ncbi.nlm.nih.gov]

Allan-Herndon-Dudley Syndrome

A lack of this critical hormone in certain parts of the brain disrupts normal brain development, resulting in intellectual disability and problems with movement. [encyclopedia.pub]

Thrombocytopenia-Absent Radius Syndrome

Children who survive infancy and do not have damaging hemorrhages in the brain usually have a normal life expectancy and normal intellectual development. [mobilitymgmt.com]

Affected children who survive this period and do not have damaging hemorrhages in the brain usually have a normal life expectancy and normal intellectual development. [ghr.nlm.nih.gov]

Hemorrhages can damage the brain and lead to intellectual disability. [ghr.nlm.nih.gov]