Normal Linear Growth: Causes & Reasons

Possible Causes for Normal Linear Growth

Abstract Diencephalic syndrome of emaciation (Russell's syndrome) characteristically presents with the symptoms of marked emaciation in spite of normal linear growth and marked [ncbi.nlm.nih.gov]

The diencephalic syndrome includes clinical characteristics of severe emaciation, normal linear growth, and normal or precocious intellectual development in association with [ncbi.nlm.nih.gov]

Craniofacial Dyssynostosis

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Autosomal Recessive Spondyloepiphyseal Dysplasia Tarda

At birth, affected males are normal in length and have normal body proportions. Affected males exhibit linear growth deficiency beginning around age six to eight years. [ncbi.nlm.nih.gov]

Affected males exhibit linear growth deficiency beginning around grade school (age 6-8 years). [ncbi.nlm.nih.gov]

At birth, affected males are normal in length and have normal body proportions. [ncbi.nlm.nih.gov]

Familial Short Stature

[…] healthy and typically have a family history suggesting short stature or delayed puberty and a normal linear growth rate parallel to the lower percentiles on the growth curve [pedclerk.bsd.uchicago.edu]

[…] and gestational weight Short stature with: Normal linear growth velocity for age Bone age consistent with chronological age Normal age for onset of puberty Absence of physical [learn.pediatrics.ubc.ca]

linear growth within the first 3 years of life. [en.wikipedia.org]

Spondyloepiphyseal Dysplasia Tarda

At birth, affected males are normal in length and have normal body proportions. Affected males exhibit linear growth deficiency beginning around age six to eight years. [ncbi.nlm.nih.gov]

Affected males exhibit linear growth deficiency beginning around grade school (age 6-8 years). [ncbi.nlm.nih.gov]

At birth, affected males are normal in length and have normal body proportions. [ncbi.nlm.nih.gov]

UNC80 Deficiency

Growth. All individuals have had normal prenatal growth. Postnatally, however, linear growth and weight remained below the 3rd centile. [ncbi.nlm.nih.gov]

Ververi-Brady Syndrome

The authors presented evidence that the chondrodysplasia resulted from impaired growth plate chondrocyte hypertrophic differentiation, a process essential for normal linear [findzebra.com]

growth. [findzebra.com]

Autosomal Dominant Spondyloepiphyseal Dysplasia Tarda

At birth, affected males are normal in length and have normal body proportions. Affected males exhibit linear growth deficiency beginning around age six to eight years. [ncbi.nlm.nih.gov]

Affected males exhibit linear growth deficiency beginning around grade school (age 6-8 years). [ncbi.nlm.nih.gov]

At birth, affected males are normal in length and have normal body proportions. [ncbi.nlm.nih.gov]

Ectopic Acromegaly

Growth hormone and insulinlike growth factor GH is necessary for normal linear growth. [emedicine.medscape.com]

Hypothalamic Adipsic Hypernatraemia Syndrome

linear growth,and mentality,and Tanner II pubic hair. [nature.com]

175 mEq/L) ↑ BUN, ↓ Hb and ↓ platelets,and urine osmolality 800-1400 mOsm/L.The levels of serum prolactin,FSH,LH, and estrogens (306 pg/ml) were high.She was obese with normal [nature.com]

Kowarski Syndrome

[…] failure. 4 non-obese boys have been identified who had normal linear growth despite apparent GH deficiency by standard RIA. [thelancet.com]

Normal growth hormone secretion in growth hormone insufficient children retested after completion of linear growth. Clin Endocrinol 45: 553, 1996. [link.springer.com]

All 4 patients had normal GH concentrations as measured with an IM-9 cell radioreceptor assay (RRA). [thelancet.com]

X-Linked Hypophosphatemia

linear growth. [ncbi.nlm.nih.gov]

Conventional treatment of XLH with oral phosphate and vitamin D fails to normalize linear growth. Objective. [ncbi.nlm.nih.gov]

The rate of linear growth is at first normal and then slowed, ultimately resulting in short stature.7 The tetany, myopathy, rachitic rosary, harrison sulcus are usually absent [jpma.org.pk]

Short Stature Type Brussels

linear growth. [enotes.com]

Overgrowth syndromes: evaluation and management of the child with excessive linear growth. In: Lifshitz F. Pediatric Endocrinology. [aafp.org]

If you are a healthy toddler, child, adolescent or young adult, and you eat an adequate number of calories each day as well as a variety of foods, you should experience normal [enotes.com]

Familial Testotoxicosis

Normal linear growth Normal bone age 19 Isolated male hormone-mediated sexual characteristics (such as pubic and/or axillary hair, acne, and apocrine odor) in boys or girls [slideplayer.com]

Precocious puberty is associated with advancement of skeletal maturity and linear growth acceleration, features which are not seen in normal variants of development. [oncohemakey.com]

Most of these girls have no other signs of pubertal development and their growth rate is normal. [slideplayer.com]

Pseudoachondroplasia

Deficiency of linear growth results from loss of chondrocytes from the growth plate. [ncbi.nlm.nih.gov]

These results suggest that the abnormality in linear growth in PSACH may result from decreased chondrocyte numbers which would also affect the amount of matrix produced. [ncbi.nlm.nih.gov]

Clinical features associated with pseudoachondroplasia include normal appearance at birth with deceleration of linear growth between the first and second years of life. [ommbid.mhmedical.com]

Congenital Sucrase-Isomaltase Deficiency

Weight gain improved with return of normal linear growth. [scholars.direct]

Direct pancreatic function testing was normal and the patient has had improved linear growth and weight gain with resolution of her diarrhea in the absence of pancreatic enzyme [scholars.direct]

Skeletal Dysplasia - Epilepsy - Short Stature Syndrome

Abnormal Growth Children whose linear growth measurements are at the extremes of the growth curve, but associated with a normal rate of growth, are likely to be normal. [endocrinologyadvisor.com]

Basic anatomy / physiology Height growth is a continuous, non-linear process with three phases: infantile, childhood, and pubertal. [learn.pediatrics.ubc.ca]

Gigantism

We presented a girl with mosaic Turner syndrome, delayed puberty and normal linear growth for the sex and age, due to the simultaneous GH hypersecretion by pituitary tumor [ncbi.nlm.nih.gov]

Growth hormone and insulinlike growth factor GH is necessary for normal linear growth. [emedicine.medscape.com]

The major clinical feature of gigantism is growth acceleration, although these patients also suffer from hypogonadism and soft tissue hypertrophy. [ncbi.nlm.nih.gov]

Growth Hormone Deficiency

After 1 year of imiglucerase replacement enzyme therapy, her bone age had normalized, linear growth rate had accelerated, and insulin growth factor-1 (IGF-1) and, perhaps [ncbi.nlm.nih.gov]

Fibromyalgia Information Foundation Adult Growth Hormone Deficiency Robert Bennett MD, FRCP Growth hormone is essential for normal linear growth and the attainment of an adult [myalgia.com]

Growth hormone (GH) is a hormone that is essential for normal growth and development in children. It promotes proper linear bone growth from birth through puberty. [labtestsonline.org]

Chiasmal Syndrome

[…] caloric intake, normal linear growth, normal intellectual development, abnormal eye movement such as nystagmus and sometimes blindness which may be from optic atrophy. [akidsbraintumorcure.org]

linear growth; none had stigmata of neurofibromatosis. [medtextfree.wordpress.com]

Growth rate usually remains linear. [bmccancer.biomedcentral.com]

Combined Pituitary Hormone Deficiency 6

However, although it is rare, growth without GH, in which patients maintain normal linear growth despite abnormal GH secretion, is also observed. [e-sciencecentral.org]

In childhood, the dominant clinical picture of hypopituitarism is often failure of normal linear growth, while in the adult it is hypogonadism. [ocw.tufts.edu]

Keywords: Growth without growth hormone, Combined pituitary hormone deficiency, Pituitary stalk interruption syndrome Introduction Normal linear growth in children along the [e-sciencecentral.org]

Juvenile Myxedema

An eleven-year-old Caucasian boy was evaluated for poor linear growth, with normal weight gain starting at the age of six and never investigated previously. [hormones.gr]

Finally, the detection of a child with impaired linear growth associated with normal weight gain should always arouse the suspicion of hypothyroidism. 4 DISCLOSURE STATEMENT [hormones.gr]

A child with poor linear growth should always be adequately investigated. [hormones.gr]

Combined Pituitary Hormone Deficiency Type 1

However, although it is rare, growth without GH, in which patients maintain normal linear growth despite abnormal GH secretion, is also observed. [e-sciencecentral.org]

The most frequently found hormone deficiency in PSIS patients is GHD, and short stature resulting from delayed growth is its typical clinical manifestation. [e-sciencecentral.org]

Mesomelic Dysplasia Type Langer

From the first months of life she had slow linear and ponderal growth, with normal psychomotor development. [bmcmedgenet.biomedcentral.com]

Functional ongoing studies are expected to improve our understanding of the SHOX gene as comprising part of a genetic process responsible for normal growth and bone development [hormones.gr]

From the first months of life she had slow linear growth with normal ponderal growth and psychomotor development. [bmcmedgenet.biomedcentral.com]

Acromegaly

Growth hormone and insulinlike growth factor GH is necessary for normal linear growth. [emedicine.medscape.com]

Individuals with AHC are depleted of both adrenal and testicular androgen supply, therefore, their linear growth in this critical period may be impaired. [datospdf.com]

Despite apparently normal hGH and IGF-1 secretion, our patient displayed progressive growth deterioration, which started around 9–10 years of chronological age. [datospdf.com]

Spondyloperipheral Dysplasia

Thus COL2A1 is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. [kr.sinobiological.com]

It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. [abcam.com]

Alglucerase

Treatment with adequate amounts of modified enzyme replacement was effective in normalizing linear growth. [ncbi.nlm.nih.gov]

Growth was compared with gender, age, and dosage of replacement enzyme. Results: Linear growth was normal in the first 1 to 2 years of life and then decelerated. [scholars.northwestern.edu]

Growth was compared with gender, age, and dosage of replacement enzyme. RESULTS: Linear growth was normal in the first 1 to 2 years of life and then decelerated. [ncbi.nlm.nih.gov]

Congenital Hypothyroidism

linear growth & intelligence 29.  In severe affected infant with lowest T4 level have reduce IQ level & neuropsychological sequelae.  Without treatment child have mental [slideshare.net]

While untreated congenital hypothyroidism results in mental retardation and poor linear growth, with early treatment patients have normal IQ and normal linear growth. [medicalhomeportal.org]

Bone maturation and linear growth are also impaired. Neurological problems may be seen in infants in whom treatment starts with a delay. [symptoma.com]

Kenney-Caffey Syndrome

However, linear growth was poor (Fig. 1c) and dentition delayed; her first tooth erupted at 16 months. [springermedizin.de]

[…] age Full size image Fig. 2 Figures 2a and 2b demonstrate the small hands and feet respectively with triangular dysplastic nails Full size image Her neurodevelopment was normal [ijpeonline.biomedcentral.com]

[…] dysplastic nails Her neurodevelopment was normal. [springermedizin.de]