Normocytic Normochromic Anemia: Causes & Reasons

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Possible Causes for Normocytic Normochromic Anemia

Toxic Hemolytic Anemia

There is normochromic and normocytic anemia picture. RDW is increased due to anisocytosis and poikilocytosis. Unlike other normochromic and normocytic anemias. [labpedia.net]

Signs and Symptoms Pallor Jaundice Lethargy Abdominal pain Low-grade fever Dark urine (sever hemolysis) Hepatosplenomegaly Diagnostic tests CBC with smear Normocytic, normochromic [pedclerk.bsd.uchicago.edu]

Coombs test direct is negative which differentiate it from autoimmune hemolytic anemia. [labpedia.net]

Anemia of Chronic Disease

Anemia of aging 3 is diagnosed in the elderly when a normocytic normochromic anemia with low iron and preserved iron stores develops without an identified underlying disease [mhmedical.com]

A number of unrelated chronic ailments are regularly associated with normocytic, normochromic anemia (see Table). [healio.com]

Before confirming on ACD, other diseases that present with normochromic and normocytic anemia should be excluded. [symptoma.com]

Glucagonoma

Similar catabolic effects with respect to protein metabolism probably cause the normochromic, normocytic anemia and hypoaminoacidemia that often are seen at initial presentation [dermaamin.com]

The serum glucose was 129 mg/dl (normal range, 70–110 mg/dl), hemoglobin was 8.4 g/dl (normal range, 12–16 g/dl) and there was a normochromic, normocytic anemia. [ncbi.nlm.nih.gov]

Usually dietary adjustment or oral administration of hypoglycemic agents can control symptoms; Anemia: it is manifested as normochromic normocytic anemia, in which the bone [tgh.amegroups.com]

Uremic Anemia

[…] of chronic kidney disease : ↓ hemoglobin, ↔︎ MCV Pathophysiology: ↓ erythropoietin → decreased stimulation of RBC production → normocytic, normochromic anemia Urinalysis [amboss.com]

A blood smear exam showed mild normocytic normochromic anemia with anisocytosis and polychromasia. [synapse.koreamed.org]

Biochemistry revealed: normocytic normochromic anemia (Hb 6 g/dL); platelet count 132 × 10 9 L −1, acute kidney injury (Urea 81 mmol/L; Creatinine 1487 μmol/L); high Lactate [medintensiva.org]

Chronic Kidney Insufficiency

Hyperphosphatemia and hyperparathyroidism are common findings, whereas a complete blood count (CBC) reveals anemia with normochromic and normocytic characteristics, thus excluding [symptoma.com]

Anemia Normochromic normocytic anemia principally develops from decreased renal synthesis of erythropoietin, the hormone responsible for bone marrow stimulation for red blood [emedicine.medscape.com]

Autoimmune Hemolytic Anemia

Clinically normochrome and normocytic anemia, reticulocytosis, polychromasia in peripheral smear, spherocytes, indirect hyperbilirubinemia and increased lactate dehydrogenase [go.gale.com]

The test also shows features of a normochromic, normocytic anemia with anisocytosis. [archivesofpathology.org]

Multiple Myeloma

Anemia is present in 80% of patients, usually normocytic-normochromic anemia with formation of rouleaux, which are clusters of 3 to 12 red blood cells that occur in stacks [msdmanuals.com]

[…] and Signs Symptoms and signs are predominantly those of the myeloma (eg, skeletal pain, pathologic fractures, diffuse osteoporosis, bacterial infections, hypercalcemia, normochromic-normocytic [merckmanuals.com]

anemia out of proportion to the degree of renal failure). [merckmanuals.com]

Polymyalgia Rheumatica

• The complete blood cell test reveals mild normocytic, normochromic anemia in 50% of cases. The white blood cell count may be normal or mildly elevated. [uspharmacist.com]

normochromic anemia, and elevation of the platelet count. [reliasmedia.com]

normocytic anemia; reactive thrombocytopenia; microscopic hematuria; and mild elevation of liver-associated enzymes also may be found. [aafp.org]

Anemia due to Glutathione Metabolism Disorder

Hemolysis results in anemia, which is usually normocytic and normochromic. Hemolysis is mostly intravascular. [pathophys.org]

This anemia is characterized as normochromic/normocytic, except when sufficient outpouring of the larger reticulocytes produces a resulting elevation of the MCV. II. [web2.iadfw.net]

microcytic, macrocytic o Hemoglobinization: normochromic, hypochromic o Shape Increased red cell destruction, or hemolysis, is one classification of anemia. [quizlet.com]

Anemia due to Infection

[…] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org]

Anemia in ART-naïve HIV patients was mostly normocytic, normochromic and characterized by a normal or low reticulocyte index suggesting 'anemia of chronic disease' as the [bmcinfectdis.biomedcentral.com]

Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org]

Congenital Hemolytic Anemia

· Diamond–Blackfan anemia Acquired: PRCA · Sideroblastic anemia · Myelophthisic Blood tests MCV ( Normocytic, Microcytic, Macrocytic ) · MCHC ( Normochromic, Hypochromic [en.academic.ru]

membrane ( PNH ) MAHA · TM ( HUS ) Drug-induced autoimmune · Drug-induced nonautoimmune Hemolytic disease of the newborn Aplastic (mostly Normo- ) Hereditary : Fanconi anemia [en.academic.ru]

Scurvy

Large hematoma on the inner right thigh After initial supportive treatment, results of primary investigations revealed a normocytic normochromic anemia with a hemoglobin level [ncbi.nlm.nih.gov]

The anemia is most often characterized as normochromic and normocytic. [web.archive.org]

Cold Agglutinin Disease

At birth, infant’s RBCs express i-antigen, which is converted to I antigen.[ 3 ] This pathologic entity is diagnosed by the presence of severe anemia (normocytic normochromic [jbclinpharm.org]

Paroxysmal Nocturnal Hemoglobinuria

and normochromic anemia Serum B12 levels 123.2 pmol/L 141–698 pmol/L Serum folate levels 45.4 nmol/L 10.4–59 nmol/L AST 2.35 ukat/L 0.167–0.667 ukat/L Bilirubin total [hindawi.com]

× 10⁹/L (2) Hb 3.4 g/dl 13.5–17.5 g/dl (3) MCV 116 fl 80–96 fl (4) PLT 123 × 10⁹/L 150–450 × 10⁹/L Reticulocyte 10.6% 0.5–2.5% Peripheral smear Pancytopenia, dimorphic, normocytic [hindawi.com]

Acquired Toxic Hemolytic Anemia

[…] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org]

Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org]

Infantile Scurvy

The anemia is most often characterized as normochromic and normocytic. [emedicine.medscape.com]

Anemia develops in 75% of patients, resulting from blood loss into tissue, coexistent dietary deficiencies (folate deficiency), altered intravascular hemolysis. [flipper.diff.org]

Rheumatoid Arthritis

A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; Hb is usually > 10 g/dL. [merckmanuals.com]

A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; hemoglobin is usually > 10 g/dL (100 g/L). [msdmanuals.com]

Primary Male Hypogonadism

Mild anemia (normochromic, normocytic)6. Increased body fat, body mass index7. Diminished physical or work performance CLINICAL PRACTIC GUIDELINE 52 53. [slideshare.net]

Islet Cell Tumor

Normochromic normocytic anemia occurs in approximately half the patients with glucagonoma, and may manifest as fatigue. [47] Somatostatinoma The symptoms of somatostatinoma [emedicine.medscape.com]

Pyruvate Kinase Deficiency

In most cases, the morphological RBC characteristics are unremarkable and are normocytic/normochromic. [clinicaladvisor.com]

The CBC may range from normocytic/normochromic presentation to increased reticulocytes, polychromatophilia, macrocytosis, and the presence of echinocytes. [clinicaladvisor.com]

The severity can range from severe neonatal anemia to a young adult with mild chronic anemia. There is considerable variation in the primary CBC markers for PKD. [clinicaladvisor.com]

Gastrointestinal Hemorrhage

This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Main Recommendations MR1. ESGE recommends immediate assessment of hemodynamic status in patients who present[…] [ncbi.nlm.nih.gov]

Upper Gastrointestinal Bleeding

Primary aortoesophageal fistula is a rare cause of upper gastrointestinal bleeding. A six-year-old boy presented with massive upper gastrointestinal hemorrhage. Endoscopy revealed a submucosal bulge in the esophagus with an ulcer and clot at the top. Lateral skiagram of the chest showed a posterior mediastinal[…] [ncbi.nlm.nih.gov]

Microcytic Anemia

Peripheral Smear Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ... [5minuteconsult.com]

Anemia, microcytic, hypochromic Anemia, microcytic, normochromic Anemia, normocytic, hypochromic Iron deficiency anemia Iron deficiency anemia of pregnancy Maternal anemia [icd9data.com]

microcytic, hypochromic Anemia, microcytic, normochromic Anemia, normocytic, hypochromic Iron deficiency anemia Iron deficiency anemia in childbirth Iron deficiency anemia [icd10data.com]

Posthemorrhagic Anaemia of the Newborn

Peripheral Smear Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ... [5minuteconsult.com]

Erythrocytes that are_________contain an abnormally low concentration of hemoglobin Normocytic-normochromic anemias include: - aplastic anemia -post hemorrhagic -hemolytic [studyblue.com]

Its prevalence increases with age, reaching 44 percent in men older than 85 years.[1] Normocytic anemia is the most frequently encountered type of anemia.[1] Contents 1… … [medicine.academic.ru]

Leukoerythroblastic Anemia

Myelophthisic anemia is a normocytic-normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. [merckmanuals.com]

Myelophthisic anemia is a normocytic, normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. [msdmanuals.com]

[…] bony lesions (myelosclerosis) characteristic of long-standing myelofibrosis or other osseous changes (ie, osteoblastic or lytic lesions of a tumor), suggesting the cause of anemia [merckmanuals.com]

Normocytic Normochromic Anemia

OBJECTIVES: Normocytic-normochromic anemia is frequently found in patients with chronic disorders. [ncbi.nlm.nih.gov]

Iron studies are frequently ordered as part of the anemia work up as iron deficiency anemia could be potentially normocytic and normochromic. [bloodjournal.org]

DESIGN: Patients with normocytic-normochromic anemia underwent a noninvasive evaluation according to a predetermined protocol. [ncbi.nlm.nih.gov]

Subphrenic Abscess

A case of left-sided subphrenic abscess, secondary to perforation of a carcinoma of stomach, is described. The patient presented with a palpable spleen which was shown to be normal in size but displaced by the subphrenic collection. The importance of correct interpretation of this physical sign is discussed. [ncbi.nlm.nih.gov]

Diffuse Cutaneous Systemic Scleroderma

Chest. 1983 Nov;84(5):546-50. Abstract The pulmonary function and chest roentgenograms were evaluated in 88 patients with the CREST syndrome variant of progressive systemic sclerosis (PSS or scleroderma). Seventy-two percent of the patients had abnormal pulmonary function. An isolated decrease in diffusing[…] [ncbi.nlm.nih.gov]

Anorexia Nervosa

Anorexia nervosa is an eating disorder characterized by a pathological fear of weight gain and usually excessive weight loss. There are two subtypes of anorexia nervosa: restricting type and binge eating–purging type. Anorexia nervosa patients present physical symptoms as well as behavioural and emotional[…] [symptoma.com]

Hodgkin Lymphoma

The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…] [ncbi.nlm.nih.gov]