Possible Causes for normocytic normochromic anemia Chronic Kidney Insufficiency Hyperphosphatemia and hyperparathyroidism are common findings, whereas a complete blood count (CBC) reveals anemia with normochromic and normocytic characteristics, thus excluding [symptoma.com] Anemia Normochromic normocytic anemia principally develops from decreased renal synthesis of erythropoietin, the hormone responsible for bone marrow stimulation for red blood [emedicine.medscape.com] Rheumatoid Arthritis A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; Hb is usually 10 g/dL. [merckmanuals.com] A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; hemoglobin is usually > 10 g/dL (100 g/L). [merckmanuals.com] Gastrointestinal Hemorrhage This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Main Recommendations MR1. ESGE recommends immediate assessment of hemodynamic status in patients who present[…] [ncbi.nlm.nih.gov] Upper Gastrointestinal Bleeding BACKGROUND & AIMS: Triage of patients with acute upper gastrointestinal hemorrhage (UGIH) has traditionally required urgent upper endoscopy. The aim of this study is to evaluate the use of artificial neural network for nonendoscopic triage. METHODS: A cohort of 387 patients was used to train (n 194) and[…] [ncbi.nlm.nih.gov] Glucagonoma Similar catabolic effects with respect to protein metabolism probably cause the normochromic, normocytic anemia and hypoaminoacidemia that often are seen at initial presentation [dermaamin.com] The serum glucose was 129 mg/dl (normal range, 70–110 mg/dl), hemoglobin was 8.4 g/dl (normal range, 12–16 g/dl) and there was a normochromic, normocytic anemia. [ncbi.nlm.nih.gov] Usually dietary adjustment or oral administration of hypoglycemic agents can control symptoms; Anemia: it is manifested as normochromic normocytic anemia, in which the bone [tgh.amegroups.com] Anemia due to Infection […] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org] Anemia in ART-naïve HIV patients was mostly normocytic, normochromic and characterized by a normal or low reticulocyte index suggesting 'anemia of chronic disease' as the [bmcinfectdis.biomedcentral.com] Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org] Multiple Myeloma Anemia is present in 80% of patients, usually normocytic-normochromic anemia with formation of rouleaux, which are clusters of 3 to 12 red blood cells that occur in stacks [msdmanuals.com] The anemia in multiple myeloma is normocytic normochromic (normal mean corpuscular volume "MCV"). Neurological symptoms include neuropathy as well as radiculopathy. [youtube.com] Autoimmune Hemolytic Anemia Signs and Symptoms Pallor Jaundice Lethargy Abdominal pain Low-grade fever Dark urine (sever hemolysis) Hepatosplenomegaly Diagnostic tests CBC with smear Normocytic, normochromic [pedclerk.bsd.uchicago.edu] Clinically normochrome and normocytic anemia, reticulocytosis, polychromasia in peripheral smear, spherocytes, indirect hyperbilirubinemia and increased lactate dehydrogenase [go.gale.com] The test also shows features of a normochromic, normocytic anemia with anisocytosis. [archivesofpathology.org] Normocytic Normochromic Anemia OBJECTIVES: Normocytic-normochromic anemia is frequently found in patients with chronic disorders. [ncbi.nlm.nih.gov] Print Feedback Export to EndNote Search: Citation Tags HERO ID 594424 Reference Type Book/Book Chapter Title The normocytic, normochromic anemia Author(s) Wintrobe, MM Year [hero.epa.gov] TOC HEME Normocytic normochromic Anemia Check for acute blood loss first. A. Primary bone marrow failure Aplastic anemia Myelophthisic anemia: a. Leukemia & lymphoma. b. [enotes.tripod.com] Paroxysmal Nocturnal Hemoglobinuria and normochromic anemia Serum B12 levels 123.2 pmol/L 141–698 pmol/L Serum folate levels 45.4 nmol/L 10.4–59 nmol/L AST 2.35 ukat/L 0.167–0.667 ukat/L Bilirubin total [hindawi.com] 10⁹/L (2) Hb 3.4 g/dl 13.5–17.5 g/dl (3) MCV 116 fl 80–96 fl (4) PLT 123 10⁹/L 150–450 10⁹/L Reticulocyte 10.6% 0.5–2.5% Peripheral smear Pancytopenia, dimorphic, normocytic [hindawi.com] Subphrenic Abscess A case of left-sided subphrenic abscess, secondary to perforation of a carcinoma of stomach, is described. The patient presented with a palpable spleen which was shown to be normal in size but displaced by the subphrenic collection. The importance of correct interpretation of this physical sign is discussed. [ncbi.nlm.nih.gov] Leukoerythroblastic Anemia Myelophthisic anemia is a normocytic-normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. [merckmanuals.com] normochromic anemia, reticulocytopenia, and bone marrow erythroblastopenia. [ncbi.nlm.nih.gov] […] bony lesions (myelosclerosis) characteristic of long-standing myelofibrosis or other osseous changes (ie, osteoblastic or lytic lesions of a tumor), suggesting the cause of anemia [merckmanuals.com] Cold Agglutinin Disease At birth, infant’s RBCs express i-antigen, which is converted to I antigen.[ 3 ] This pathologic entity is diagnosed by the presence of severe anemia (normocytic normochromic [jbclinpharm.org] Diffuse Cutaneous Systemic Scleroderma Chest. 1983 Nov;84(5):546-50. Abstract The pulmonary function and chest roentgenograms were evaluated in 88 patients with the CREST syndrome variant of progressive systemic sclerosis (PSS or scleroderma). Seventy-two percent of the patients had abnormal pulmonary function. An isolated decrease in diffusing[…] [ncbi.nlm.nih.gov] Anorexia Nervosa It is important to recognise that patients who seek weight loss surgery may have a history of restrictive eating or anorexia nervosa. The following case report describes a woman with a history of anorexia nervosa who underwent Roux-en-Y gastric bypass surgery. Her eating disorder symptoms subsequently[…] [ncbi.nlm.nih.gov] Uremic Anemia A blood smear exam showed mild normocytic normochromic anemia with anisocytosis and polychromasia. [synapse.koreamed.org] […] of chronic kidney disease : hemoglobin, ︎ MCV Pathophysiology: erythropoietin decreased stimulation of RBC production normocytic, normochromic anemia Urinalysis : : possibly [amboss.com] Biochemistry revealed: normocytic normochromic anemia (Hb 6 g/dL); platelet count 132 10 9 L 1, acute kidney injury (Urea 81 mmol/L; Creatinine 1487 μmol/L); high Lactate [medintensiva.org] Islet Cell Tumor Normochromic normocytic anemia occurs in approximately half the patients with glucagonoma, and may manifest as fatigue. [47] Somatostatinoma The symptoms of somatostatinoma [emedicine.medscape.com] Toxic Hemolytic Anemia Signs and Symptoms Pallor Jaundice Lethargy Abdominal pain Low-grade fever Dark urine (sever hemolysis) Hepatosplenomegaly Diagnostic tests CBC with smear Normocytic, normochromic [pedclerk.bsd.uchicago.edu] There is normochromic and normocytic anemia picture. RDW is increased due to anisocytosis and poikilocytosis. Unlike other normochromic and normocytic anemias. [labpedia.net] anemia Reticulocytosis (or rare reticulocytopenia) Spherocytes, schistocytes, poikilocytes, polychromasia Normal WBC and Platelets (except in Evan’s syndrome) DAT (Direct [pedclerk.bsd.uchicago.edu] Hodgkin Lymphoma The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…] [ncbi.nlm.nih.gov] Congenital Hemolytic Anemia · Diamond–Blackfan anemia Acquired: PRCA · Sideroblastic anemia · Myelophthisic Blood tests MCV ( Normocytic, Microcytic, Macrocytic ) · MCHC ( Normochromic, Hypochromic [en.academic.ru] membrane ( PNH ) MAHA · TM ( HUS ) Drug-induced autoimmune · Drug-induced nonautoimmune Hemolytic disease of the newborn Aplastic (mostly Normo- ) Hereditary : Fanconi anemia [en.academic.ru] Splenic Rupture A 50-year-old man was diagnosed with multiple myeloma complicating AL amyloidosis. Splenic rupture was complicated during autologous stem cell transplantation (auto-SCT). Granulocyte colony-stimulating factor (G-CSF) was not administered. A pathological examination of the spleen revealed that CD34-positive cells were[…] [ncbi.nlm.nih.gov] Retroperitoneal Hemorrhage We encountered complications of septic shock and retroperitoneal hemorrhage which occurred after implantation of a retrievable Günther Tulip filter. A 79-year-old woman was diagnosed as right femoral vein thrombosis, and a retrievable Günther Tulip filter was deployed prior to a total knee replacement surgery.[…] [ncbi.nlm.nih.gov] Anemia of Chronic Disease Anemia of aging 3 is diagnosed in the elderly when a normocytic normochromic anemia with low iron and preserved iron stores develops without an identified underlying disease [mhmedical.com] A number of unrelated chronic ailments are regularly associated with normocytic, normochromic anemia (see Table). [healio.com] The anemia of chronic disease is primarily an anemia due to underproduction of red cells, with low reticulocyte production, and is most often a normochromic, normocytic anemia [ncbi.nlm.nih.gov] Exsanguination Abstract We describe our experience using a new device that results in a bloodless field in open repair of distal radius fractures. The device, an exsanguinating tourniquet (HemaClear model/40, OHK Medical Devices, Haifa, Israel), replaces the traditional methods of limb elevation, Esmarch bandaging, pneumatic[…] [ncbi.nlm.nih.gov] Fetal Erythroblastosis To present intensive intrauterine treatment of recurrent early onset fetal erythroblastosis due to anti-M alloimmunization. A 33-year-old woman, gravid 3, para 1, had anti-M IgG antibody, which caused alloimmunization of her previous pregnancies. This time she visited our hospital for intensive intervention. No evidence[…] [ncbi.nlm.nih.gov] Acquired Toxic Hemolytic Anemia […] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org] Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org] Malignant Neoplasm ICD-10-CM Codes › C00-D49 Neoplasms › C76-C80 Malignant neoplasms of ill-defined, other secondary and unspecified sites › C80- Malignant neoplasm without specification of site › Malignant neoplasm without specification of site 2016 2017 2018 2019 Non-Billable/Non-Specific Code C80 should not be used for reimbursement[…] [icd10data.com] Hemoperitoneum Surg Clin North Am. 2014 Feb;94(1):65-9. doi: 10.1016/j.suc.2013.10.006. Epub 2013 Oct 30. Author information 1 Section of Trauma & Acute Care Surgery, Boston Medical Center, Boston University School of Medicine, 840 Harrison Avenue, Dowling 2 South, #2414, Boston, MA 02118, USA. Electronic address: gkasot@bu.edu.[…] [ncbi.nlm.nih.gov] Primary Male Hypogonadism Mild anemia (normochromic, normocytic)6. Increased body fat, body mass index7. Diminished physical or work performance CLINICAL PRACTIC GUIDELINE 52 53. [slideshare.net] Hemolytic Transfusion Reaction Alloantibodies to the low-frequency antigen Scianna-2 (Sc2) have been implicated in cases of hemolytic disease of the fetus and newborn but never in hemolytic transfusion reactions (HTRs); thus, the clinical significance of anti-Sc2 has yet to be fully addressed. A 26-year-old woman with thalassemia presented[…] [ncbi.nlm.nih.gov]
