Normocytic Normochromic Anemia: Causes & Reasons

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Possible Causes for Normocytic Normochromic Anemia

Anemia of Chronic Disease

Anemia of aging 3 is diagnosed in the elderly when a normocytic normochromic anemia with low iron and preserved iron stores develops without an identified underlying disease [mhmedical.com]

A number of unrelated chronic ailments are regularly associated with normocytic, normochromic anemia (see Table). [healio.com]

Before confirming on ACD, other diseases that present with normochromic and normocytic anemia should be excluded. [symptoma.com]

Toxic Hemolytic Anemia

There is normochromic and normocytic anemia picture. RDW is increased due to anisocytosis and poikilocytosis. Unlike other normochromic and normocytic anemias. [labpedia.net]

Signs and Symptoms Pallor Jaundice Lethargy Abdominal pain Low-grade fever Dark urine (sever hemolysis) Hepatosplenomegaly Diagnostic tests CBC with smear Normocytic, normochromic [pedclerk.bsd.uchicago.edu]

Coombs test direct is negative which differentiate it from autoimmune hemolytic anemia. [labpedia.net]

Glucagonoma

Similar catabolic effects with respect to protein metabolism probably cause the normochromic, normocytic anemia and hypoaminoacidemia that often are seen at initial presentation [dermaamin.com]

The serum glucose was 129 mg/dl (normal range, 70–110 mg/dl), hemoglobin was 8.4 g/dl (normal range, 12–16 g/dl) and there was a normochromic, normocytic anemia. [ncbi.nlm.nih.gov]

Usually dietary adjustment or oral administration of hypoglycemic agents can control symptoms; Anemia: it is manifested as normochromic normocytic anemia, in which the bone [tgh.amegroups.com]

Uremic Anemia

[…] of chronic kidney disease : ↓ hemoglobin, ↔︎ MCV Pathophysiology: ↓ erythropoietin → decreased stimulation of RBC production → normocytic, normochromic anemia Urinalysis [amboss.com]

A blood smear exam showed mild normocytic normochromic anemia with anisocytosis and polychromasia. [synapse.koreamed.org]

Biochemistry revealed: normocytic normochromic anemia (Hb 6 g/dL); platelet count 132 × 10 9 L −1, acute kidney injury (Urea 81 mmol/L; Creatinine 1487 μmol/L); high Lactate [medintensiva.org]

Chronic Kidney Insufficiency

Hyperphosphatemia and hyperparathyroidism are common findings, whereas a complete blood count (CBC) reveals anemia with normochromic and normocytic characteristics, thus excluding [symptoma.com]

Anemia Normochromic normocytic anemia principally develops from decreased renal synthesis of erythropoietin, the hormone responsible for bone marrow stimulation for red blood [emedicine.medscape.com]

Autoimmune Hemolytic Anemia

Clinically normochrome and normocytic anemia, reticulocytosis, polychromasia in peripheral smear, spherocytes, indirect hyperbilirubinemia and increased lactate dehydrogenase [go.gale.com]

The test also shows features of a normochromic, normocytic anemia with anisocytosis. [archivesofpathology.org]

Multiple Myeloma

Anemia is present in 80% of patients, usually normocytic-normochromic anemia with formation of rouleaux, which are clusters of 3 to 12 red blood cells that occur in stacks [msdmanuals.com]

[…] and Signs Symptoms and signs are predominantly those of the myeloma (eg, skeletal pain, pathologic fractures, diffuse osteoporosis, bacterial infections, hypercalcemia, normochromic-normocytic [merckmanuals.com]

anemia out of proportion to the degree of renal failure). [merckmanuals.com]

Polymyalgia Rheumatica

• The complete blood cell test reveals mild normocytic, normochromic anemia in 50% of cases. The white blood cell count may be normal or mildly elevated. [uspharmacist.com]

normocytic anemia; reactive thrombocytopenia; microscopic hematuria; and mild elevation of liver-associated enzymes also may be found. [aafp.org]

normocytic anemia Aching, pain, and morning stiffness in the shoulders and upper arms, hips and thighs, or neck and torso Symptoms of systemic inflammation (e.g., anorexia [aafp.org]

Anemia due to Infection

[…] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org]

Anemia in ART-naïve HIV patients was mostly normocytic, normochromic and characterized by a normal or low reticulocyte index suggesting 'anemia of chronic disease' as the [bmcinfectdis.biomedcentral.com]

Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org]

Anemia due to Glutathione Metabolism Disorder

Hemolysis results in anemia, which is usually normocytic and normochromic. Hemolysis is mostly intravascular. [pathophys.org]

This anemia is characterized as normochromic/normocytic, except when sufficient outpouring of the larger reticulocytes produces a resulting elevation of the MCV. II. [web2.iadfw.net]

microcytic, macrocytic o Hemoglobinization: normochromic, hypochromic o Shape Increased red cell destruction, or hemolysis, is one classification of anemia. [quizlet.com]

Congenital Hemolytic Anemia

· Diamond–Blackfan anemia Acquired: PRCA · Sideroblastic anemia · Myelophthisic Blood tests MCV ( Normocytic, Microcytic, Macrocytic ) · MCHC ( Normochromic, Hypochromic [en.academic.ru]

membrane ( PNH ) MAHA · TM ( HUS ) Drug-induced autoimmune · Drug-induced nonautoimmune Hemolytic disease of the newborn Aplastic (mostly Normo- ) Hereditary : Fanconi anemia [en.academic.ru]

Rheumatoid Arthritis

A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; Hb is usually > 10 g/dL. [merckmanuals.com]

A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; hemoglobin is usually > 10 g/dL (100 g/L). [msdmanuals.com]

Cold Agglutinin Disease

At birth, infant’s RBCs express i-antigen, which is converted to I antigen.[ 3 ] This pathologic entity is diagnosed by the presence of severe anemia (normocytic normochromic [jbclinpharm.org]

Paroxysmal Nocturnal Hemoglobinuria

and normochromic anemia Serum B12 levels 123.2 pmol/L 141–698 pmol/L Serum folate levels 45.4 nmol/L 10.4–59 nmol/L AST 2.35 ukat/L 0.167–0.667 ukat/L Bilirubin total [hindawi.com]

× 10⁹/L (2) Hb 3.4 g/dl 13.5–17.5 g/dl (3) MCV 116 fl 80–96 fl (4) PLT 123 × 10⁹/L 150–450 × 10⁹/L Reticulocyte 10.6% 0.5–2.5% Peripheral smear Pancytopenia, dimorphic, normocytic [hindawi.com]

Acquired Toxic Hemolytic Anemia

[…] color (normocytic, normochromic) but as the anemia progresses, the RBCs become smaller ( microcytic ) and paler ( hypochromic ) than normal. [labtestsonline.org]

Results may show: Hemoglobin (Hb)—may be normal early in the disease but will decrease as anemia worsens Red blood cell indices—early on, the RBCs may be a normal size and [labtestsonline.org]

Scurvy

Large hematoma on the inner right thigh After initial supportive treatment, results of primary investigations revealed a normocytic normochromic anemia with a hemoglobin level [ncbi.nlm.nih.gov]

The anemia is most often characterized as normochromic and normocytic. [web.archive.org]

Islet Cell Tumor

Normochromic normocytic anemia occurs in approximately half the patients with glucagonoma, and may manifest as fatigue. [47] Somatostatinoma The symptoms of somatostatinoma [emedicine.medscape.com]

Primary Male Hypogonadism

Mild anemia (normochromic, normocytic)6. Increased body fat, body mass index7. Diminished physical or work performance CLINICAL PRACTIC GUIDELINE 52 53. [slideshare.net]

Infantile Scurvy

The anemia is most often characterized as normochromic and normocytic. [emedicine.medscape.com]

Anemia develops in 75% of patients, resulting from blood loss into tissue, coexistent dietary deficiencies (folate deficiency), altered intravascular hemolysis. [flipper.diff.org]

Pyruvate Kinase Deficiency

In most cases, the morphological RBC characteristics are unremarkable and are normocytic/normochromic. [clinicaladvisor.com]

The CBC may range from normocytic/normochromic presentation to increased reticulocytes, polychromatophilia, macrocytosis, and the presence of echinocytes. [clinicaladvisor.com]

The severity can range from severe neonatal anemia to a young adult with mild chronic anemia. There is considerable variation in the primary CBC markers for PKD. [clinicaladvisor.com]

Gastrointestinal Hemorrhage

This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Main Recommendations MR1. ESGE recommends immediate assessment of hemodynamic status in patients who present[…] [ncbi.nlm.nih.gov]

Upper Gastrointestinal Bleeding

Primary aortoesophageal fistula is a rare cause of upper gastrointestinal bleeding. A six-year-old boy presented with massive upper gastrointestinal hemorrhage. Endoscopy revealed a submucosal bulge in the esophagus with an ulcer and clot at the top. Lateral skiagram of the chest showed a posterior mediastinal[…] [ncbi.nlm.nih.gov]

Leukoerythroblastic Anemia

Myelophthisic anemia is a normocytic-normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. [merckmanuals.com]

Myelophthisic anemia is a normocytic, normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. [msdmanuals.com]

[…] bony lesions (myelosclerosis) characteristic of long-standing myelofibrosis or other osseous changes (ie, osteoblastic or lytic lesions of a tumor), suggesting the cause of anemia [merckmanuals.com]

Normocytic Normochromic Anemia

OBJECTIVES: Normocytic-normochromic anemia is frequently found in patients with chronic disorders. [ncbi.nlm.nih.gov]

Presentation on theme: "Normocytic Normochromic Anemias"— Presentation transcript: 1 Normocytic Normochromic Anemias M H Qari, MD, FRCPA Associate Professor of Hematology [slideplayer.com]

@article{Elis1996ACA, title={A clinical approach to "idiopathic" normocytic-normochromic anemia.}, author={Avishay Elis and Mordchai Ravid and Yosef Manor and Tamir Bental [semanticscholar.org]

Subphrenic Abscess

A case of left-sided subphrenic abscess, secondary to perforation of a carcinoma of stomach, is described. The patient presented with a palpable spleen which was shown to be normal in size but displaced by the subphrenic collection. The importance of correct interpretation of this physical sign is discussed. [ncbi.nlm.nih.gov]

Diffuse Cutaneous Systemic Scleroderma

Chest. 1983 Nov;84(5):546-50. Abstract The pulmonary function and chest roentgenograms were evaluated in 88 patients with the CREST syndrome variant of progressive systemic sclerosis (PSS or scleroderma). Seventy-two percent of the patients had abnormal pulmonary function. An isolated decrease in diffusing[…] [ncbi.nlm.nih.gov]

Anorexia Nervosa

Anorexia nervosa Other names Anorexia "Miss A—" depicted in 1866 and in 1870 after treatment. She was one of the earliest case studies of anorexia. From the published medical papers of William Gull. Specialty Psychiatry, Clinical psychology Symptoms Low weight, fear of gaining weight, strong desire to be thin, food[…] [en.wikipedia.org]

Microcytic Anemia

Peripheral Smear Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ... [5minuteconsult.com]

Anemia, microcytic, hypochromic Anemia, microcytic, normochromic Anemia, normocytic, hypochromic Iron deficiency anemia Iron deficiency anemia of pregnancy Maternal anemia [icd9data.com]

microcytic, hypochromic Anemia, microcytic, normochromic Anemia, normocytic, hypochromic Iron deficiency anemia Iron deficiency anemia in childbirth Iron deficiency anemia [icd10data.com]

Hodgkin Lymphoma

The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…] [ncbi.nlm.nih.gov]

Splenic Rupture

Atraumatic rupture of the normal spleen is a rare entity. Often, a triggering factor or minor physical event can be ascribed as the aetiology for rupture, including coughing, vomiting or minor medical procedures not involving the spleen. A 65-year-old man who was hospitalised for eosinophilic pneumonia developed[…] [ncbi.nlm.nih.gov]