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229 Possible Causes for Normocytic Normochromic Anemia, Thrombocytosis

  • Malignant Neoplasm

    Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs). We report a case of colorectal carcinoma as a SMN, following treatment for rhabdomyosarcoma. The patient was[…][]

  • Congenital Hemolytic Anemia

    Diamond–Blackfan anemia Acquired: PRCA Sideroblastic anemia Myelophthisic Blood tests MCV Normocytic Microcytic Macrocytic MCHC Normochromic Hypochromic Other Methemoglobinemia[] […] coagulability primary: Antithrombin III deficiency · Protein C deficiency / Activated protein C resistance / Protein S deficiency / Factor V Leiden · Hyperprothrombinemia acquired: Thrombocytosis[] Laboratory studies (Table 1 ) showed severe microcytic and hypochromic anemia with reticulocytopenia, a normal white blood cell count and thrombocytosis.[]

  • Anemia of Chronic Disease

    Anemia of aging 3 is diagnosed in the elderly when a normocytic normochromic anemia with low iron and preserved iron stores develops without an identified underlying disease[] Essential thrombocytosis (primary thrombocythemia): The body produces too many platelets, due to an unknown cause; the platelets do not work properly, resulting in excessive[] A number of unrelated chronic ailments are regularly associated with normocytic, normochromic anemia (see Table).[]

  • Primary Myelofibrosis

    Normocyticnormochromic anemia is present in most, but not all, patients (see Table 91–2). 7–15,262–265 Mean hemoglobin concentration in a series of patients at diagnosis[] To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[] A 61-year-old woman with transfusion-dependent normochromic, normocytic anemia (hemoglobin 6.0 g/dL) was admitted to our department.[]

  • Acute Myelocytic Leukemia

    Anemia It is primarily a normocytic normochromic anemia, which typically increases on induction chemotherapy. It is to be managed with recurrent blood transfusion.[] Here we report a case of AML with thrombocytosis arising in a patient with this syndrome.[] Jubinsky PT: Megakaryopoiesis and thrombocytosis. Pediatr Blood Cancer 44 (1): 45-6, 2005.[]

  • Sideroblastic Anemia

    Peripheral Smear Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ...[] A unique patient with sideroblastic anemia and thrombocytosis with a recurrent and ultimately fatal thromboembolic phenomenon is described.[] We believe this is the first reported case of trisomy 8 with trilineage myelodysplasia and thrombocytosis with primary acquired sideroblastic anemia.[]

  • Myeloproliferative Disease

    RBCs: -Normocytic normochromic anemia -mild poikilocytosis -polychromatophilia & NRBCs -DACROCYTES WBCs: -Initial leukocytosis with immature neutrophils (BANDS) Platelets:[] One patient clearly represents a case of RARS with reactive thrombocytosis.[] As controls we considered 61 patients with reactive thrombocytosis referred to our Department in the same period of time.[]

  • Splenic Rupture

    […] presents with elevated WBC's, fevers, pleuritic pain, and left shoulder pain (referred from phrenic nerve irritation) Hematologic findings - due to decreased splenic clearance thrombocytosis[] (see differential diagnoses below) References: [3] Diagnostics Laboratory tests : low Hb , leukocytosis , and thrombocytosis ; crossmatch for blood transfusion if needed In[] The activating mutation JAK2V617F is frequently found in myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocytosis and PMF ( 20 ).[]

  • Myelofibrosis

    normocytic anemia with leukoerythroblastosis.[] Thrombocytosis is more common than thrombocytopenia.[] Leucocytosis, thrombocytosis, and postoperative hepatic enlargement are the usual consequences of splenectomy, as is elevation of liver alkaline phosphatase.[]

  • Polymyalgia Rheumatica

    . • The complete blood cell test reveals mild normocytic, normochromic anemia in 50% of cases. The white blood cell count may be normal or mildly elevated.[] Anemia of chronic disease, leukocytosis, reactive thrombocytosis, and decreased albumin are also common. Alkaline phosphatase and hepatic enzymes may be elevated.[] , normocytic anemia; reactive thrombocytopenia; microscopic hematuria; and mild elevation of liver-associated enzymes also may be found.[]

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