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91 Possible Causes for Nystagmus in Adult Patients

  • Alpha-Mannosidosis

    Alpha-mannosidosis is a lysosomal storage disorder, first described by Swedish physician Okerman in 1967. In humans it is known to be caused by an autosomal recessive genetic mutation in the gene MAN2B1, located on chromosome 19, affecting the production of the enzyme alpha-D-mannosidase, resulting in its deficiency.[…][en.wikipedia.org]

  • Polyneuropathy

    Ataxia and Polyneuropathy, Adult-Onset Clinical Characteristics Ocular Features: This condition has its onset in young adults.[disorders.eyes.arizona.edu] Early ocular signs are gaze-evoked horizontal nystagmus and defective ocular pursuit movements with the full range of extraocular movements.[disorders.eyes.arizona.edu] Some patients but not all have optic atrophy. Ptosis is not present. Systemic Features: Gait disturbances have their onset in the first or second decades of life.[disorders.eyes.arizona.edu]

  • Brain Stem Infarction

    In younger adults, it may occur due to multiple sclerosis (MS), commonly with bilateral involvement.[emedicine.medscape.com] In elderly patients, INO is caused most often by occlusion of the basilar artery or its paramedian branches.[emedicine.medscape.com] […] of CN III (in the midbrain) and CN VI (in the pons) results in the inability of the eye ipsilateral to the lesion to adduct and the contralateral eye to exhibit abduction nystagmus[emedicine.medscape.com]

  • Vestibular Neuronitis

    With regard to directional nystagmus, the gaze was bilateral in five patients and vertical in two.[ncbi.nlm.nih.gov] However, among adults, 24% of patients felt persisting unsteadiness.[ncbi.nlm.nih.gov] The patients recovered within two to four weeks, a prognosis which is better than that observed in adults.[ncbi.nlm.nih.gov]

  • Eye Muscle Disorder

    This small preliminary trial will include five adult patients with congenital nystagmus who have no other treatment options.[clinicaltrials.gov] The initiation of Phase II begins with enrollment of 5 adults and after review of 1 week post-surgical safety data, 5 patients under the age of 18 will be enrolled.[clinicaltrials.gov] Patients who have a clinical and oculographic diagnosis of congenital nystagmus as determined by a screening exam at NEI and have not had previous extraocular muscle surgery[clinicaltrials.gov]

  • Familial or Sporadic Hemiplegic Migraine

    MRIs of the brain in patients with SCA6 reveal cerebellar atrophy [ 6 ].[karger.com] […] cerebellar ataxia, dysarthria and oculomotor disturbances consisting of gaze-evoked nystagmus, gaze paresis and diplopia.[karger.com] […] generalized ataxia with or without migraine, whereas SCA6 is associated with a CAG repeat expansion in the CACNA1A gene and is clinically characterized predominantly by adult-onset[karger.com]

  • Nystagmus

    Other rare forms of nystagmus or abnormal eye movements, such as pendular nystagmus, ocular oscillation or flutter were recorded in only four patients.[ncbi.nlm.nih.gov] Clinical diagnosis and frequency distribution of patients with nystagmus within Leicestershire calculated by CRC statistical method.[doi.org] This small preliminary trial will include five adult patients with congenital nystagmus who have no other treatment options.[clinicaltrials.gov]

  • Central Positional Vertigo

    Patient Resources Learn more about: Nystagmus. BPPV. the home Epley procedure.[hopkinsmedicine.org] […] studied in a randomized clinical trials of adult patients.[eyewiki.aao.org] To request an appointment or refer a patient, please contact the Vestibular Disorder Staff at 410-955-3319.[hopkinsmedicine.org]

  • Idiopathic Bilateral Vestibulopathy

    Subject Adult; Head Movements; Humans; Male; Nystagmus, Pathologic/complications; Reflex, Vestibulo-Ocular/physiology; Vestibular Diseases/complications; Vestibular Diseases[collections.lib.utah.edu] Two Types of Oscillopsia in a Patient with Idiopathic Vestibulopathy Page Metadata Title Two Types of Oscillopsia in a Patient with Idiopathic Vestibulopathy Creator Acierno[collections.lib.utah.edu] […] physiopathology; Vision Disorders/classification; Vision Disorders/etiology; Vision Disorders/physiopathology; Visual Acuity Abstract A patient with an idiopathic bilateral[collections.lib.utah.edu]

  • Abducens Nerve Palsy

    MRI is indicated for any brainstem findings to exclude pontine glioma in children (most have papilledema and nystagmus without other cranial nerve involvement) and in adults[emedicine.com] In young adults, a lumbar puncture (LP) for cerebrospinal fluid (CSF) analysis is completed to exclude meningitis in patients who have no history of diabetes or hypertension[emedicine.com]

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