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927 Possible Causes for Obesity, T Cell Activation Increased

  • Essential Hypertension

    RESULTS: Compared with non-H-type hypertensive patients, CD4 T-cell percentage in peripheral blood was significantly decreased in H-type hypertensive patients.[ncbi.nlm.nih.gov] Abdominal obesity is a risk factor for cardiovascular disease worldwide, and it is becoming a dramatic issue for national health systems.[ncbi.nlm.nih.gov] Role of renin–angiotensin system in obesity hypertension.[doi.org]

  • Insulin Resistance

    Augmented enzymatic activity of glucokinase in β-cells. J. Clin. Invest. 94, 399–404 (1994). 42 Liu, Y. Q., Jetton, T. L. & Leahy, J.[doi.org] Obese women pregnancy runs on the background of hypertriglyceridemia and type IV hyperlipoproteinemia.[ncbi.nlm.nih.gov] Furthermore, we explore how the ATX-LPA pathway impacts obesity and obesity-associated disorders, including impaired glucose homeostasis, insulin resistance, and cardiovascular[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    A fluorescence activated cell sorting analysis showed an altered T-cell population.[ncbi.nlm.nih.gov] CONTEXT: Obesity and diabetes are increasing in the United States. OBJECTIVE: To estimate the prevalence of obesity and diabetes among US adults in 2001.[ncbi.nlm.nih.gov] CD is a T-cell mediated disorder where gliadin derived peptides activate immune cells in the gut lamina propria and recruit infiltrating T lymphocytes, which initiate an adaptive[mdpi.com]

  • Hypertension

    38 T cells play an important role in Ang II infusion, desoxycorticosterone acetate-salt–induced hypertension, and associated vascular and renal dysfunctions. 39 – 41 The T-cell[doi.org] This epidemic of pediatric obesity has resulted in great concern regarding the management of obesity and its complications.[doi.org] Obesity has become an increasingly important medical problem in children and adolescents.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus Type 2

    Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection.[doi.org] SSB and Childhood Obesity Childhood obesity is known to increase risk of obesity in adulthood and can lead to serious consequences for T2DM and cardiovascular disease risk[doi.org] CONCLUSION: rs10767664 polymorphism of BDNF gene is associated with prevalence of diabetes mellitus in obese female patients.[ncbi.nlm.nih.gov]

  • Dysthymic Disorder

    Also, depression was accompanied by an increased number of activated T cells (CD25 and HLA-DR ), secretion of neopterin, prostaglandin E2 and thromboxane.[doi.org] SSRI have been shown to be effective in the treatment of obesity, 55 panic, 56 alcohol and smoking cessation, 57 premenstrual syndrome, 58 attention deficit disorder, 59 post[orthomolecular.org]

  • Malnutrition

    Arginase activity Enhanced arginase-induced L-arginine depletion is increasingly recognized as a key mechanism of T cell suppression [ 33 ] and we have shown that increased[journals.plos.org] KEYWORDS: Africa; East Africa; Uganda; malnutrition; nutrition; obesity; overweight[ncbi.nlm.nih.gov] The first 2 are more easily recognized, but the third may be more often unnoticed, particularly in obese patients.[ncbi.nlm.nih.gov]

  • Hypothyroidism

    Consistent with their playing a fundamental role, an increased proportion of activated T-helper (Th) (CD4 ) cells can be demonstrated in the circulation of a majority of patients[ncbi.nlm.nih.gov] SCFE usually occurs during puberty, with obesity a common risk factor.[ncbi.nlm.nih.gov] The increased inward flux of Na that results from this hormonal action amplifies cell depolarization and may also contribute to activation of membrane Na, K-ATPase or Na [ncbi.nlm.nih.gov]

  • Klinefelter Syndrome

    It has been hypothesized that testosterone protects males from autoimmune phenomena; therefore, hypogonadal males are prone to defects in T-cell activity that lead to autoimmune[glowm.com] Obesity is reported to have adverse effects on semen quality and the endocrine system.[ncbi.nlm.nih.gov] […] systemic lupus erythematosus, 63 , 64 , 65 ankylosing spondylitis, 66 and Sjögren’s syndrome, characterized by keratoconjunctivitis, dry mouth, and arthritis, 65 occur with increased[glowm.com]

  • Streptococcus Pneumoniae

    An interplay of mast cells, T lymphocytes, and epithelial cells results in a circulatory surge of inflammatory cells as well as cytokines.[ncbi.nlm.nih.gov] The continuing epidemics of obesity and diabetes in the United States. JAMA 2001 ; 286 : 1195 – 200. 10.[academic.oup.com] Patient 4 A 38-year-old obese man underwent elective laparoscopic fundoplication for weight control. Eighteen hours later, he developed fever and abdominal pain.[journals.lww.com]

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