Possible Causes for onset at age 20 Kearns-Sayre Syndrome Kearns-Sayre syndrome (KSS) is a neuromuscular disorder defined by the triad of onset before age 20 years, pigmentary retinopathy (a "salt-and-pepper" pigmentation in the [rarediseases.info.nih.gov] […] before age 20, and severe cardiac conduction defects that can lead to death. [ncbi.nlm.nih.gov] Abstract Kearns-Sayre syndrome (KSS) is a sporadic multisystem mitochondrial disorder characterized by progressive external ophthalmoplegia, pigmentary retinopathy, onset [ncbi.nlm.nih.gov] Urinary Tract Infection ] In older children, new onset urinary incontinence (loss of bladder control) may occur.[20] About 1 in 400 infants of 1 to 3 months of age with a UTI also have bacterial [en.wikipedia.org] […] than a year exhibit a fever, a culture of the urine is recommended by many medical associations.[20] Infants may feed poorly, vomit, sleep more, or show signs of jaundice.[20 [en.wikipedia.org] Cystitis ] In older children, new onset urinary incontinence (loss of bladder control) may occur.[20] About 1 in 400 infants of 1 to 3 months of age with a UTI also have bacterial [en.wikipedia.org] […] than a year exhibit a fever, a culture of the urine is recommended by many medical associations.[20] Infants may feed poorly, vomit, sleep more, or show signs of jaundice.[20 [en.wikipedia.org] Juvenile Huntington Disease BACKGROUND: Juvenile Huntington disease (JHD) is a rare clinical entity characterized by an age at onset younger than 20 years. [ncbi.nlm.nih.gov] Abstract The age of onset distribution of Huntington disease (HD) has been defined for siblings of patients who exhibit the disease before age 20. [ncbi.nlm.nih.gov] Abstract Juvenile Huntington disease (HD), characterised by onset of symptoms before the age of 20 with rigidity and intellectual decline, is associated with a predominance [ncbi.nlm.nih.gov] Menopause For women who initiate HT more than 10 or 20 years from menopause onset or are aged 60 years or older, the benefit-risk ratio appears less favorable because of the greater [ncbi.nlm.nih.gov] 60 or who are 10 to 20 years past menopause onset. [msdmanuals.com] […] pulmonary embolism, stroke, breast cancer; low risk of gallbladder disease, stress urinary incontinence); potential harms are greater for women who start hormone therapy after age [msdmanuals.com] Insomnia Among 292 citations and 91 full-text articles reviewed, 20 studies (1162 participants [64% female; mean age, 56 years]) were included. [ncbi.nlm.nih.gov] Insomnia frequency 3 times per week and sleep onset latency 10-20 min were second-level predictors. [ncbi.nlm.nih.gov] Efficacy Low-dose (20-mg) and high-dose (40-mg) suvorexant in individuals younger than age 65 years both proved superior to placebo in the following categories: waking after [ncbi.nlm.nih.gov] Essential Hypertension The age at onset of hypertension in the maternal kindred varied from 20 years to 69 years, with an average of 44 years. [ncbi.nlm.nih.gov] Renal vascular hypertension should be suspected in the following circumstances: (1) if the documented onset is before age 20 or after age 50 years, (2) hypertension is resistant [health.am] Alcohol Abuse […] at ages 20 or older. [ncbi.nlm.nih.gov] RESULTS: Participants with an earlier age of onset of drinking regularly scored higher on the Michigan Alcoholism Screening Test (MAST) and drank more frequently to get high [ncbi.nlm.nih.gov] […] years of age, the period of greatest risk for the onset of an alcohol use disorder (AUD). [doi.org] Hypertension Gestational age Hypertension prior to 20 weeks' gestation is almost always due to chronic hypertension; preeclampsia is rare prior to the third trimester. [web.archive.org] Gestational age Hypertension before 20 weeks' gestation is almost always due to chronic hypertension; new-onset or worsening hypertension after 20 weeks' gestation should [emedicine.medscape.com] New-onset or worsening hypertension after 20 weeks' gestation should lead to a careful evaluation for manifestations of preeclampsia. [web.archive.org] Depression The typical age of onset is in the 20s, but it may occur at any age. Depression can have many causes. [britannica.com] Sexually Transmitted Disease The risk factors for gonorrhea include young age (15- to 19-year- old age group in women and 20- to 24-year old age group in men), low socioeconomic status, early onset of [web.archive.org] The incidence of sepsis was 20% in newborns with 28 weeks and 58% among newborns with a gestational age of 22 weeks(8). [scielo.br] Signs and symptoms of early onset sepsis may be subtle and mimic other diseases. Presentation varies somewhat based on gestational age of the neonate. [cancertherapyadvisor.com] Acne Vulgaris Mean age of the study group was 19.78 years. Male to female ratio was 1.25:1. The most common age group involved was 16 to 20 years (59.8%). [dx.doi.org] Age of onset: typically by 11–12 years, with symptoms usually disappearing around 20–30 years of age Sex: more common in males during adolescence, but more common in women [amboss.com] Historical and physical clues that may suggest hormone-sensitive acne include onset between ages 20 and 30; worsening the week before a woman's period; acne lesions predominantly [en.wikipedia.org] Acute Respiratory Infection People ages 20 to 77 signed up and received kits (Figure 3), and 70% of signups were women. Kits were returned by individuals ranging in age from 20 to 70. [currents.plos.org] Fig. 2: Days between symptom onset and specimen submission. [currents.plos.org] Participants submitted kits an average of 3.29 (95% CI: 2.39, 4.18) days after symptom onset (Figure 2). [currents.plos.org] Substance Abuse The second are “late-onset” individuals who begin abusing substances later in life. [buffalo.edu] The first are long-term substance users who have reached age 65. [buffalo.edu] This group is projected to expand in number as the elderly population in the U.S. increases over the next 20 years. [buffalo.edu] Atopy […] of children and 1% to 3% of adults.4,5 Onset of disease is most common by 5 years of age, and early diagnosis and treatment are essential to avoid complications of AD and [ajmc.com] In the adult population, the rate of AD frequency is 3% or higher, but onset may be delayed until adulthood. Prognosis Most patients improve; this can occur at any age. [emedicine.medscape.com] suggesting that this may account for the common perception that AD resolves over time.13 In contrast, a 2016 meta-analysis showed that only 20% of childhood AD persisted [ajmc.com] Dermatitis […] of children and 1% to 3% of adults.4,5 Onset of disease is most common by 5 years of age, and early diagnosis and treatment are essential to avoid complications of AD and [ajmc.com] Age The usual onset occurs with puberty. It peaks at age 40 years and is less severe, but present, among older people. [emedicine.medscape.com] In the adult population, the rate of AD frequency is 3% or higher, but onset may be delayed until adulthood. Prognosis Most patients improve; this can occur at any age. [emedicine.com] Atopic Dermatitis Less than 2% will have an onset after age 20 years. Most sources agree that persistence after age 20 years is uncommon. [emedicine.medscape.com] […] of children and 1% to 3% of adults.4,5 Onset of disease is most common by 5 years of age, and early diagnosis and treatment are essential to avoid complications of AD and [ajmc.com] […] before age 7 years. [emedicine.medscape.com] Periodontitis […] older than 5 years at onset, absence of corneal endotheliopathy and female gender were found to be associated with best corrected visual acuity (BCVA) of 20/40.[7] Another [ncbi.nlm.nih.gov] […] common causes of severe visual loss were macular edema in 64%, cataract in 21% and retinal detachment in 14% of cases.[13] In the other study, better baseline visual acuity, age [ncbi.nlm.nih.gov] Bacterial Vaginosis METHODS: Women aged 20-49, who had experienced one or more symptomatic episode of BV within 6 months, were opportunistically recruited to complete a 38-item questionnaire [ncbi.nlm.nih.gov] […] extend and validate the findings of our earlier smaller qualitative study by exploring in detail women's views and experiences of the triggering factors associated with BV onset [ncbi.nlm.nih.gov] Hypogonadism In men 20-50 years of age are often identified when undergoing evaluation for infertility and/or sexual dysfunction. [symptoma.com] 75 V (young adult): 12-60 *Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 ( /-2) years and for girls at a median [mayomedicallaboratories.com] The initial presentation of hypogonadism in men depends upon the age of onset. Prepubescent boys present with delayed secondary sex characteristics and puberty. [symptoma.com] Hay Fever The usual onset is before age 20. [web.archive.org] […] diagnosed before the age of 20. [patient.info] Epidemiology [ 6 ] Allergic rhinitis is a common problem, affecting over 20% of the UK population. [ 7 ] School-aged children and adolescents are more likely to have seasonal [patient.info] Sacral Radiculopathy […] of onset (bimodal -- Age 20 years or Age 55 years) A full neurologic exam shoulder is performed, including an assessment for upper motor neuron findings (Babinski sign, clonus [ncbi.nlm.nih.gov] […] night, pain at rest, unexplained weight loss, or night sweats Significant medical comorbidities Neurologic deficit or serial exam deterioration Gait ataxia Saddle anesthesia Age [ncbi.nlm.nih.gov] Allergic Rhinitis The usual onset is before age 20. [web.archive.org] […] diagnosed before the age of 20. [patient.info] Epidemiology [ 6 ] Allergic rhinitis is a common problem, affecting over 20% of the UK population. [ 7 ] School-aged children and adolescents are more likely to have seasonal [patient.info] Labor The age of onset is over 20 years, with most patients aged 45-60 years. [orpha.net] Polymyositis usually affects adults older than 20 years, especially those aged 45-60 years. Polymyositis rarely affects children. [emedicine.medscape.com] The age of onset of polymyositis with another collagen vascular disease is related to the associated condition. [emedicine.medscape.com] Obesity This association was statistically significant among adults (aged 20-59 years and or 60 years) but not among younger persons (aged 20 years). [ncbi.nlm.nih.gov] The neurobiology of middle-age has arrived. Neurobiol Aging 2009 ; 30 : 515 -20. Nilsson LG, Sternang O, Ronnlund M, Nyberg L. [dx.doi.org] Women who reported having a larger body size, using the silhouettes, at age 20 also had a twofold increased risk of MS as compared to women who reported a thinner body size [ncbi.nlm.nih.gov] Birth The age of onset is over 20 years, with most patients aged 45-60 years. [orpha.net] Polymyositis usually affects adults older than 20 years, especially those aged 45-60 years. Polymyositis rarely affects children. [emedicine.medscape.com] The age of onset of polymyositis with another collagen vascular disease is related to the associated condition. [emedicine.medscape.com] Puerperium The age of onset is over 20 years, with most patients aged 45-60 years. [orpha.net] Polymyositis usually affects adults older than 20 years, especially those aged 45-60 years. Polymyositis rarely affects children. [emedicine.medscape.com] The age of onset of polymyositis with another collagen vascular disease is related to the associated condition. [emedicine.medscape.com] Scoliosis […] before three years or above 10 years of age. [scoliosisjournal.com] Spine. 2003, 28 (20): 2397-2406. [doi.org] We found 30 patients (Table 1 ), 27 females and 3 males, 10 with a diagnosis of JIS type 1 and 20 with type 2; mean age at first diagnosis was 7.8 1.5 and mean treatment lasted [scoliosisjournal.com] Raynaud Syndrome Epidemiology Affects 3-4% of U.S. adult population Predominately affects women by 3 to 1 ratio Onset from Puberty to age 30 years Family History responsible in 20-30% of patients [fpnotebook.com] Both of these may be further classified as either juvenile or adult onset. The juvenile onset form occurs prior to age 20 and frequently prior to age 10. [en.wikipedia.org] While the genetic cause of the juvenile and sporadic adult onset forms is often known, this is not the case for the adult onset familial form.[9] In rural areas of southern [en.wikipedia.org] Arthritis Whites and women have a poorer prognosis, as do patients with subcutaneous nodules, advanced age at disease onset, inflammation in 20 joints, early erosions, cigarette smoking [merckmanuals.com]
