Possible Causes for onset at age 4 years Neuronal Ceroid Lipofuscinosis Type 9 […] between ages 2 and 4 years Epilepsy Cognitive decline Ataxia Myoclonus Extrapyramidal symptoms Pyramidal symptoms Blindness at age 4-6 years Death before or in the second [emedicine.staging.medscape.com] In this family, onset of the disorder occurred at 4 to 5 years of age, with affected children becoming silent, taciturn, and irritable. [cags.org.ae] All our cases did not fit well with the typical clinicopathologic descriptions, therefore representing atypical variants of JNCL or vLINCL due to the late onset at 4-7 years [pediatricneurosciences.com] Acute Alcohol Intoxication View Article PubMed PubMed Central Google Scholar Grant BF, Stinson FS, Harford TC: Age at onset of alcohol use and DSM-IV alcohol abuse and dependence: a 12-year follow-up [bmcemergmed.biomedcentral.com] J Subst Abuse. 2001, 13 (4): 493-504. [bmcemergmed.biomedcentral.com] Musculoskeletal Lower Back Pain 6 weeks Infection ( Spinal Epidural Abscess, Vertebral Osteomyelitis, Diskitis) Age 50 years increases risk Insidious onset Fever and/or chills; absence of fever does not [blog.thesullivangroup.com] […] thrombolytic therapy Malignancy Age 50 years History of cancer Pain worse at night or when lying supine Unexplained weight loss Persistent or worsening pain lasting more than 4- [blog.thesullivangroup.com] Hypertension (ie needs 4 therapeutic agents); young age (consider specialist assessment for those under the age of 40 years [ 7 ] ). [patient.info] Possible underlying cause: low K , Na elevated (possible Conn's syndrome); elevated creatinine, proteinuria or haematuria; sudden-onset or rapidly worsening or resistant hypertension [patient.info] Essential Hypertension Renal vascular hypertension should be suspected in the following circumstances: (1) if the documented onset is before age 20 or after age 50 years, (2) hypertension is resistant [health.am] (ie needs 4 therapeutic agents); young age (consider specialist assessment for those under the age of 40 years [ 7 ] ). [patient.info] […] to three or more drugs, (3) if there are epigastric or renal artery bruits, (4) if there is atherosclerotic disease of the aorta or peripheral arteries (15-25% of patients [health.am] Alcohol Abuse In fact, research has showed that the percentage of adolescents who consume alcohol progressively increases with age and that the onset age is 12 years old(4). [scielo.br] At the same time, scientific evidence suggests that early onset is associated to future behavioral problems in adolescence, including violence related to alcohol, accidents [scielo.br] Stomatitis Approximately 1% of American children may have recurrent aphthous ulcers, with onset before age 5 years. [emedicine.medscape.com] Age Recurrent aphthous ulcer minor is the most common form of childhood recurrent aphthous ulcer. [emedicine.medscape.com] 50.3% [13] Sex In children and in some adult communities who are affected, the incidence of recurrent aphthous ulcer is higher in women and girls than in men or boys. [4] [emedicine.medscape.com] Acne Vulgaris Nearly 90% of teenagers have acne, and half of them continue to experience symptoms as adults. 1 2 3 By age 40 years, 1% of men and 5% of women still have lesions. 4 Recent [doi.org] It is primarily considered a disease of teenagers—with 85% to 90% of all teenagers having some degree of acne. 4 Although acne generally resolves by age 25 years, there is [consultant360.com] Pediatric acne can be further subdivided based on the age of onset of the disease: neonatal acne occurs from birth through age 4 weeks; infantile acne has its onset between [dx.doi.org] Malnutrition Onset is from age 3-15 months with disappearance by 3 or 4 years. Rarely, it may be present to age 5-6 years. [emedicine.medscape.com] Atopy Onset of less than age 2 years (not used unless child is under 4 years of age). [hawaii.edu] - History of generally dry skin over the last year. - Visible flexural eczema (or eczema involving cheeks, forehead, extensor limbs in children under age of 4 years). - [hawaii.edu] Food Allergy Late-onset peanut allergy at age 4 years was rare (0.2%). [ncbi.nlm.nih.gov] At age 4 years, peanut allergy prevalence was 1.9% (95% CI, 1.6% to 2.3%), egg allergy was 1.2% (95% CI, 0.9% to 1.6%), and sesame allergy was 0.4% (95% CI, 0.3% to 0.6%). [ncbi.nlm.nih.gov] Pharyngitis GAS infection is most common in children aged 4-7 years. Sudden onset is consistent with a GAS pharyngitis. [web.archive.org] Nevertheless, the following factors may help rule out or diagnose GAS pharyngitis: GAS infection is most common in children aged 4-7 years Sudden onset is consistent with [emedicine.com] Hyperuricemia We retrospectively analyzed the patients records for symptoms at onset, BMI, HbA1c and treatment for a maximum of 4 years. [ncbi.nlm.nih.gov] PATIENTS AND METHODS: At the moment we care for three patients with type 2 diabetes (two girls and one boy) age 16 - 17 years. [ncbi.nlm.nih.gov] Hay Fever The adjusted IRR was 4 overall and ranged between 3 and 5 within the three age groups. [ncbi.nlm.nih.gov] Patients with MDE had early-onset MDD (first MDE prior to age 45 years). Health or MDE was confirmed using the Structured Clinical Interview for DSM-IV 30 ( Table 1 ). [dx.doi.org] Restricting the analysis to those participants, who were 17-25 years of age at the end of follow-up resulted in similar IRR. [ncbi.nlm.nih.gov] Atopic Dermatitis Onset in the first two years of life (not always diagnostic in children aged under 4 years). If it does not itch it is very unlikely to be eczema. [patient.info] • Visible flexural dermatitis (i.e., in the bends or folds of the skin at the elbow, knees, wrists, etc.) • Onset under age 2 years Children 4 years:* • History of itching [aacijournal.biomedcentral.com] Visible flexural eczema (or eczema affecting the cheeks or forehead and outer limbs in children aged under 4 years). [patient.info] Scoliosis Juvenile: Developing between 4-9 years of age. [physioclinic.ie] Scoliosis can be categorised according to the age of the individual at onset. These are as follows: Infantile: Manifests from birth to age 3. [physioclinic.ie] Raynaud Syndrome carpal tunnel syndrome, intervertebral disc disease Pulmonary hypertension Onset usually 30 years of age References:[1][2][3][4] Clinical features Manifestation Ischemic [amboss.com] The patients with primary RP have a younger age of onset (below 30 years), sparing of the thumb, and benign course without the development of digital ulcers [4, 6, 7]. [intechopen.com] Epidemiology Affects 3-4% of U.S. adult population Predominately affects women by 3 to 1 ratio Onset from Puberty to age 30 years Family History responsible in 20-30% of patients [fpnotebook.com] Fibroma (Hospital No. 180082), aged 40 years, was admitted to the Graduate Hospital on November 4, 1947, with chief complaints of shortness of breath and chest pain of two years duration [journal.chestnet.org] Onset of symptoms had followed a severe “cold,” and they had become more marked three months prior to admission. [journal.chestnet.org] Arthritis It can appear at any age, but onset is most likely is between the ages of 15 and 45 years. For every one man who gets lupus, between 4 and 12 women will do so. [medicalnewstoday.com] Geographic Tongue Results The mean age of the patient group was 33.8 /- 18.2 years (4–79 years). [link.springer.com] The mean age of onset of disease was 26 /-17.7 years (0–74 years), 23 /-18.8 years in women and 27.6 /- 17.0 years in men. [link.springer.com] Allergic Rhinitis Patients with MDE had early-onset MDD (first MDE prior to age 45 years). Health or MDE was confirmed using the Structured Clinical Interview for DSM-IV 30 ( Table 1 ). [dx.doi.org] Healthy controls were age matched within 4 years to the patients with MDE. [dx.doi.org] Influenza The median age of patients who died was 26 years (range, 1.3 to 57); the median time from the onset of illness to death was 15 days (range, 4 to 52). [nejm.org] Ménière Disease The mean age of 44 years at the onset of MD in our subjects is in agreement with previous reports. [jamanetwork.com] it has been described in children as young as 4 years and in elderly persons older than 90 years. [3] The typical onset begins at early to middle adulthood. [emedicine.com] According to the 12% occurrence of bilateral MD in their study, the mean duration since the onset of disease could be roughly estimated to be 10 years. [jamanetwork.com] Restless Legs Syndrome The mean age at onset was 26 5.87 years. Age at RLS onset was 26 years for the deceased II‐4, while it was not known for the founder I‐1. [doi.org] Medication: mianserin 30mg daily, started after onset of tinnitus; carbamazepine recently added with no effect on tinnitus. Case 4: Female, aged 70. [benzo.org.uk] Age at onset in this family ranged from 18 (III‐11) to 28 (II‐6 and II‐8) years. Only in one individual (III‐7) was onset delayed, at 42 years. [doi.org] Raynaud Disease Epidemiology Affects 3-4% of U.S. adult population Predominately affects women by 3 to 1 ratio Onset from Puberty to age 30 years Family History responsible in 20-30% of patients [fpnotebook.com] Lactose Intolerance However, this entity only exceptionally causes symptoms before the age of 4-5 years. [ncbi.nlm.nih.gov] The vast majority of Asian children will develop late onset congenital lactase deficiency. [ncbi.nlm.nih.gov] Hemorrhoids Usual onset 45–65 years of age[5] Duration Few days[3] Causes Unknown[4] Risk factors Constipation, diarrhea, sitting on the toilet for a long time, pregnancy[3] Diagnostic [en.wikipedia.org] […] internal and external hemorrhoids Pronunciation Specialty General surgery Symptoms Internal: Painless, bright red rectal bleeding[3] External: Pain and swelling around the anus[4] [en.wikipedia.org] Polyps 45 years, rather than the standard age of 50 years. [4, 5] Males appear to have a moderately higher colonic polyp incidence than females, with earlier onset observed in some [emedicine.medscape.com] […] studies. [6] Colonic polyps are strongly associated with increasing age (typically after age 40 y), but they can occur early in patients with polyposis syndromes. [emedicine.medscape.com] Task Force on Colorectal Cancer as well as those from the American Gastroenterological Association (AGA) recommend beginning colorectal cancer screening in black persons at age [emedicine.medscape.com] Temporomandibular Joint Disorder Age Highest incidence is among young adults, especially women aged 20-40 years. Schiffman E, Ohrbach R. [emedicine.medscape.com] Such symptoms also had an earlier onset in Caucasians. Sex Temporomandibular disorder primarily affects women with a male-to-female ratio of 1:4. [emedicine.medscape.com] Bronchial Asthma Asthma resolves in many children, but for as many as 1 in 4, wheezing persists into adulthood or relapse occurs in later years. [merckmanuals.com] Female sex, smoking, earlier age of onset, and sensitization to household dust mites, are risk factors for persistence and relapse. [merckmanuals.com]
