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166 Possible Causes for Onset at Age 5-10 Years, Restless Legs Syndrome, Weakness

  • Diabetes Mellitus Type 2

    CONCLUSIONS: Our data suggest that chemerin is a weak predictor of T2DM. 2015 John Wiley & Sons Ltd.[ncbi.nlm.nih.gov] Epidemiology Type 1 : 5% of all patients with diabetes Childhood onset ; : typically 20 years but can occur at any age; peaks at age 4–6 years and 10–14 years Highest prevalence[amboss.com] CONCLUSION: This cross-sectional study has shown a weak association of irisin with physical activity levels in healthy controls but not in DMT2 subjects, suggesting the possibility[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    Facial numbness and weakness are also common.[medical-dictionary.thefreedictionary.com] […] and especially early age at onset, are associated with a better course. [13] [114] The average life expectancy is 30 years from the start of the disease, which is 5 to 10[en.wikipedia.org] Her symptoms started at the age of 29 years with insidious onset of pyramidal weakness in the left leg.[ncbi.nlm.nih.gov]

  • Multiple Sclerosis

    syndrome (RLS).[ncbi.nlm.nih.gov] […] motor weakness had recovered.[ncbi.nlm.nih.gov] Table 1 Patient demographics Female 319 (64%) Male 178 (36%) Age 5 (1%) 21–30 86 (17%) 31–40 151 (30%) 41–50 143 (29%) 60 112 (23%) Onset 143 (29%) 5–10 years ago 177 (36%[dx.doi.org]

  • Diabetic Neuropathy

    He also had weakness of hip flexion.[ncbi.nlm.nih.gov] […] of DM Symptomatic evidence 5 years: 4% to 10% 25 years: 13% to 15% Mean time after DM onset: 8 years Increased Frequency: Women; Increased Age Objective evidence (Clinical[neuromuscular.wustl.edu] The pain and muscle weakness had persisted more severely in the shoulder than in the thigh throughout the clinical course.[ncbi.nlm.nih.gov]

  • Narcolepsy-Cataplexy Syndrome

    The editors and contributing authors are internationally recognized authorities who cover everything from sleep and ADHD, headaches, restless leg syndrome, parasomnias, hypersomnias[books.google.de] Partial weakness - specifically ask patients about partial weakness (eg, mild facial or jaw weakness), which they may not report.[patient.info] In craniopharyngiomas, the onset of cataplectic symptoms is between 5-10 years of age, which is earlier than the peak of narcolepsy with cataplexy in children around the second[scholarpedia.org]

  • Postural Orthostatic Tachycardia Syndrome

    Some people with POTS experience restless leg syndrome, something that may be relieved through treatment of POTS.[disabled-world.com] The most common symptoms of POTS include light-headedness or dizziness, palpitations, fainting, near-fainting, intermittent muscle weakness (commonly in the legs), and fatigue[digitalcommons.hsc.unt.edu] POTS has an estimated prevalence of at least 170 out of 100,000 people, with an age range of 15-50 years, a mean age at onset of 30 years, and a female-to-male ratio of 5:[karger.com]

  • Charcot-Marie-Tooth Disease Type 2S

    Abstract Article abstract In a series of 44 consecutive patients with Charcot-Marie-Tooth disease (CMT), we found restless legs syndrome (RLS) in 10 of 27 CMT type 2 (CMT2[neurology.org] Definition An axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the[uniprot.org] Age at onset of symptoms was before 10 years in 21 patients (84%). Eight patients (32%) experienced their first symptoms before age 5 years.[jamanetwork.com]

  • Multifocal Motor Neuropathy

    Restless legs syndrome (RLS) has been frequently reported in association with peripheral neuropathy, and it is especially frequent in some forms of polyneuropathy with preferential[ncbi.nlm.nih.gov] RESULTS: We identified 3 patients with hand weakness and 1 patient with asymmetric weakness of the upper extremity. Conduction blocks (CBs) were identified in 1 patient.[ncbi.nlm.nih.gov] 2 Patient 1 2 3 4 5 6 7 8 9 10 11 Clinical features Sex M M F M M M M M M M M Age at onset (years) 47 30 31 42 30 43 20 48 40 38 58 Site of onset UL LL UL UL UL LL LL UL UL[brain.oxfordjournals.org]

  • Classic Progressive Supranuclear Palsy Syndrome

    The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome,[books.google.com] However, muscle atrophy, weakness, evidence of denervation on electromyography, vertical gaze palsy, parkinsonism, gait freezing, aphasia, speech apraxia, or dementia was[okayama.pure.elsevier.com] The progression of the disease is slow between 5 to 10 years. The age of onset is typically over 50 years old. The duration of the disease is 7 years.[alzheimer-europe.org]

  • Parasomnia Type Sleepwalking

    Restless legs syndrome and periodic limb movement disorder Restless legs syndrome and periodic limb movement disorder are treated with 3 classes of medications.[emedicinehealth.com] Approach to the Patient with Diplopia 117 Approach to the Patient with Facial Numbness 125 Approach to the Patient with Facial Pain 136 Approach to the Patient with Facial Weakness[books.google.ro] Fifty percent of patients (37/74) had a self-reported disease onset before the age of 10 years, whereas only 6.8% (5/74) reported a disease onset after the age of 30 years[jcsm.aasm.org]

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