If GAA activity is less severely reduced, patients may not develop any symptoms until adolescence or adulthood. They may then be diagnosed with late-onset GSD2.
Antenatal, Neonatal, Infancy, Childhood, Adolescent, Adult ICD-10: E74.0 OMIM: 232300 UMLS: C0017921 MeSH: D006009 GARD: 5714 MedDRA: 10053185 The documents contained in
Less severe reductions of GAA activity result in late-onset GSD2. Adolescents or adults may experience progressive muscle weakness, breathing and walking difficulties.