Onset in Adolescence: Causes & Reasons

Possible Causes for Onset in Adolescence

Schizophrenia with onset before adolescence does seem to differ from later-onset cases in the very high rates of insidious as opposed to acute onset. [academic.oup.com]

Onset of schizophrenia is typically from mid-adolescence to the mid-30s, with a peak age of onset in the 20s. Features in adolescents and young adults are similar. [merckmanuals.com]

[…] ratio does not truly distinguish childhood-onset from (young) adult-onset forms of the disorder. [academic.oup.com]

Lafora Disease

With the exception of a few missense mutations LD is clinically homogeneous, with onset in adolescence. [ncbi.nlm.nih.gov]

The disease course is progressive and fatal, with death occurring within 10 years of onset. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2E

onset of progressive pelvic- and shoulder-girdle muscle weakness, particularly affecting the pelvic girdle (adductors and flexors of hip). [orpha.net]

Adolescent, Childhood ICD-10: G71.0 OMIM: 608099 UMLS: C1842550 C2936332 MeSH: - GARD: 438 MedDRA: - The documents contained in this web site are presented for information [orpha.net]

Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. [fpnotebook.com]

Juvenile Cystinosis

[…] cystinosis Adolescent cystinosis, late-onset cystinosis, juvenile cystinosis Adult cystinosis, benign cystinosis, ocular cystinosis It is believed that cystinosis affects [cystaran.com]

Late-onset juvenile or adolescent nephropathic cystinosis is an intermediated form, manifesting first at age 10 to 12 years with proteinuria due to glomerular damage rather [genecards.org]

"The late-onset or adolescent form of cystinosis accounts for about 5% of cases and is very under-recognized," he said. [raredr.com]

Kleine-Levin Syndrome

[…] during adolescence. [ncbi.nlm.nih.gov]

He emphasized 4 clinical features: males principally affected, onset during adolescence, eventual spontaneous disappearance, and the possibility that overeating is of the [medlink.com]

Critchley 1962 : Predominance in adolescent males; Onset in adolescence; Periodic hypersomnia; Hyper/mega/polyphagia; Associated behavioural and psychological changes; Benign [doi.org]

Cerebrotendinous Xanthomatosis

The four main clinical features that help clinicians diagnose CTX are infantile-onset diarrhea, childhood-onset cataract, adolescent to young adult-onset tendon xanthomas, [ncbi.nlm.nih.gov]

Neurological dysfunction is almost always present, with onset usually in late adolescence or early adulthood (12) (Figure 2). [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2G

(ranging from infancy to adolescence) of progressive proximal upper and lower limb muscle weakness and atrophy. [orpha.net]

[…] definitionAutosomal recessive limb-girdle muscular dystrophy type 2G (LGMD2G) is a mild subtype of autosomal recessive limb-girdle muscular dystrophy characterized by a variable onset [malacards.org]

In most cases, childhood onset of LGMD results in a more severe disorder that progresses more rapidly than adolescent or adult onset cases. [rarediseases.org]

X-linked Distal Spinal Muscular Atrophy Type 3

Adolescent, Adult, Infancy, Childhood ICD-10: G12.2 OMIM: 300489 UMLS: C1845359 MeSH: - GARD: - MedDRA: - The documents contained in this web site are presented for information [orpha.net]

LATE ADOLESCENCE/ ADULTHOOD (adult-onset) LATE ADOLESCENCE/ADULTHOOD (adult-onset) 1,2,4 Highest motor milestone achieved ALL Life expectancy (untreated SMA) NORMAL Clinical [togetherinsma-hcp.com]

It onsets at some point between adolescence and mid-life and symptoms include generalised muscle weakness, cramping and spasms, as well as difficulties with speech and swallowing [www2.warwick.ac.uk]

Progressive Myoclonic Epilepsy Type 7

Abstract Many of the progressive epilepsy syndromes with adolescent onset are classified as progressive myoclonus epilepsies. [thieme-connect.com]

[…] in adolescence or in late childhood; progresses to death between 17–24 years in 90% of patients Generalized tonic-clonic seizures are presenting features; status epilepticus [neurodiffdx.com]

Rare diseases Search Search for a rare disease Progressive myoclonic epilepsy type 7 Disease definition A rare, genetic, neurological disorder characterized by childhood to adolescent [orpha.net]

Autosomal Dominant Spastic Paraplegia Type 17

ORPHA:100998 Synonym(s): SPG17 Silver syndrome Spastic paraplegia-amyotrophy of hands and feet Prevalence: Inheritance: Autosomal dominant Age of onset: Childhood, Adolescent [orpha.net]

ORPHA:100988 Synonym(s): SPG6 Prevalence: Inheritance: Autosomal dominant Age of onset: Childhood, Adolescent, Adult ICD-10: G11.4 OMIM: 600363 UMLS: C1838192 MeSH: C536866 [orpha.net]

Woodhouse-Sakati Syndrome

Movement disorders mainly consist of dystonia and chorea of the limbs with onset in adolescence. Facial muscles are usually spared, but dysarthria is common. [ncbi.nlm.nih.gov]

Usual onset during adolescence. [sites.uclouvain.be]

Clinical description The onset is usually in adolescence. [orpha.net]

Autosomal Recessive Anterior Segment Dysgenesis

It is characterized by the onset of adolescence, the central visual impairment and the frequent appearance of orange-yellow spots. [diploidegenetics.com]

Neuronal Ceroid Lipofuscinosis Type 6

[…] in adolescents and adults. [pesquisa.bvsalud.org]

Others may not develop symptoms until adolescence and may live into adulthood. [ninds.nih.gov]

[…] on chromosome 15q21-23 present three types of clinical variants late childhood CLN6, presenting between 18 months to 8 years, the Kufs type A and Kufs type B variants of onset [pesquisa.bvsalud.org]

Segmental Dystonia

Childhood onset – 0 to age 12 Adolescent onset – age 13 to 20 Adult onset – older than age 20 Focal dystonia is limited to one area of the body and can affect the neck (cervical [aans.org]

However, there are specific primary dystonias with childhood or adolescent onset that have been linked to genetic mutations. [aans.org]

The younger one is at onset, the greater the chance that symptoms will spread. [aans.org]

Charcot-Marie-Tooth Disease Type 2E

ORPHA:99939 Classification level: Disorder Synonym(s): CMT2E Prevalence: Unknown Inheritance: Autosomal dominant Age of onset: Childhood, Adolescent, Adult, Infancy ICD-10 [orpha.net]

Charcot-Marie-Tooth disease usually becomes apparent in adolescence or early adulthood, but onset may occur anytime from early childhood through late adulthood. [ghr.nlm.nih.gov]

Extraocular Muscle Myopathy

Similar articles A rapidly progressive adolescent-onset oculopharyngeal somatic syndrome with rimmed vacuoles in two siblings. [pubmed.ncbi.nlm.nih.gov]

Breast Papillomatosis

Papillomatosis of the breast Other names Juvenile papillomatosis, Swiss cheese disease Specialty Breast surgery, Surgical oncology Usual onset Children, adolescents, adult [en.wikipedia.org]

Primary Dystonia Type DYT2

Onset Primary; Mixed Type Autosomal Dominant Adolescent onset, mostly segmental, rarely generalizes DYT-7 18pter-p11.32 Adult Onset Focal Primary Autosomal Dominant Adult [cmdg.org]

With regard to primary dystonia type DYT2 or DYT2-like primary dystonia (PD-DYT2), symptom onset occurs in childhood or adolescence. [symptoma.com]

Proximal Myopathy with Focal Depletion of Mitochondria

ORPHA:521305 Classification level: Disorder Synonym(s): - Prevalence: <1 / 1 000 000 Inheritance: - Age of onset: Childhood, Adolescent, Adult ICD-10: - OMIM: 600706 UMLS: [orpha.net]

[…] in adolescence Muscle: severe myalgias after exercise mild proximal weakness Lab: elevated creatine kinase large areas of about one-third of type ii muscle fibers devoid [malacards.org]

31 HP:0003236 2 proximal muscle weakness 31 HP:0003701 3 exercise-induced myalgia 31 HP:0003738 Symptoms via clinical synopsis from OMIM®: 57 (Updated 05-Apr-2021) Misc: onset [malacards.org]

Hemiparkinsonism

ORPHA:306669 Classification level: Disorder Synonym(s): HP-HA syndrome Prevalence: <1 / 1 000 000 Inheritance: - Age of onset: Adult, Adolescent ICD-10: G20 OMIM: - UMLS: [orpha.net]

Exhibitionism

Onset is usually during adolescence; occasionally, the first act occurs during preadolescence or middle age. [msdmanuals.com]

Distal Hereditary Motor Neuropathy Type 5A

139536 Synonym(s): Distal HMN V Distal hereditary motor neuropathy type V Distal spinal muscular atrophy type 5 dHMN5 Prevalence: - Inheritance: Autosomal dominant Age of onset [orpha.net]

Symptoms of distal hereditary motor neuropathy, type V usually begin during adolescence, but onset varies from infancy to the mid-thirties. [ghr.nlm.nih.gov]

Familial Dyskinesia and Facial Myokymia

A rare paroxysmal movement disorder with onset in childhood or adolescence. [ncbi.nlm.nih.gov]

The disorder has an early childhood or adolescent onset. [ncbi.nlm.nih.gov]

onset of paroxysmal choreiform, myoclonic, and/or dystonic movements that involve the limbs, neck, and/or face. [checkorphan.org]

Fibrosis - Neurodegeneration - Cerebral Angiomatosis

Here we present two unusual cases of PASH: an adolescent patient with bilateral rapid onset of symptoms, and a premenopausal patient with bilateral, diffuse, recurrent PASH [pesquisa.bvsalud.org]

GLB1-Related Disorders

In its severe form, the age of onset is between one and three years. Some individuals have an attenuated form, with onset in late childhood or adolescence. [myriad.com]

Schizophrenia Type 1

Citation metadata Abstract : The onset of schizophrenia in children and adolescents is polymorphic and can be expressed by an acute psychosis, lucid or confused, by a surprising [go.gale.com]

Nephronophthisis 12

[…] of onset 10 adolescent (a.k.a. medullary cystic kidney disease): usually develops in patients in their thirties There can be clinical triad comprising of uremia, anemia, [radiopaedia.org]

Juvenile - median age of onset 13 years. Adolescent - median age of onset 19 years. [patient.info]

onset is 13 years), and adolescent (median age at onset is 19 years). [patientslikeme.com]

Ectodermal Dysplasia with Natal Teeth Type Turnpenny

Onset generally occurs during adolescence. Some patients are born with multiple teeth. Hair anomalies (sparse body and scalp hair) also reported. [ncbi.nlm.nih.gov]

Onset generally occurs during adolescence. Some patients were born with multiple teeth. Hair anomalies (sparse body and scalp hair) were also reported. [malacards.org]

Adult Neuronal Ceroid Lipofuscinosis

\ ˈku̇fs- \ Medical Definition of Kufs' disease : a hereditary lipid metabolism defect with onset usually in adolescence and characterized by progressive convulsions, paralysis [merriam-webster.com]

Symptoms of Kufs disease may onset anywhere between adolescence and adulthood. However, signs and symptoms typically onset about 30 years of age. [symptoma.com]

Myoadenylate Deaminase Deficiency

Onset is in childhood or adolescence in nearly 50% of cases. [accessanesthesiology.mhmedical.com]