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37 Possible Causes for Onset of Dysarthria in Third Decade of Life, Tremor

  • Ataxia

    An adult patient with cerebrotendinous xanthomatosis exhibited ataxia and palatal tremor in the absence of tendon xanthomas and cataracts.[ncbi.nlm.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Case description: The patient was a 53-year-old female farmer with severe tremor in the upper limbs at rest that worsens with movement, tremor in the jaw and tongue, and generalized[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 1

    Among SCA2 patients, bradykinesia was the most frequent (35.3%), followed by reduced facial expression, postural tremor and dystonia (29.4% each), rest tremor, titubation[ncbi.nlm.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.com] […] features of individuals carrying 39 uninterrupted CAG repeats did not differ from the SCA1 phenotype in general with dysphagia, pale discs, pyramidal signs and cerebellar tremor[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 12

    Action tremor, anxiety, and depression in SCA12 have responded to usual treatments for these disorders.[ncbi.nlm.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] In 90% patients, tremor was presenting symptom. Action and postural tremor were present in all of them but rest tremor was present in 80 % patients.[mdsabstracts.org]

  • Hallervorden-Spatz Syndrome

    […] arm and resting tremor in upper extremities.[ncbi.nlm.nih.gov] Clinical features Dystonia Dysarthria Spasticity Choreoathetosis Parkinsonism Hyperreflexia Extensor toe signs Onset in first to third decade of life Gait change / loss of[ncbi.nlm.nih.gov] Motor incoordination, dystonia, and tremor progressed until the patient was wheel-chair-bound.[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 20

    The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects.[books.google.es] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] In addition to ataxia, examination often reveals spasmodic dysphonia and palatal tremor, but the syndrome is otherwise fairly pure.[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 5

    The onset of symptoms is usually in the third or fourth decade of life; however, more subtle clinical manifestations can start in early childhood.[ncbi.nlm.nih.gov] We developed a mouse lacking full-length beta-III spectrin and found that homozygous mice reproduced features of SCA5 including gait abnormalities, tremor, deteriorating motor[ncbi.nlm.nih.gov] Non-cerebellar signs such as facial myokimia, resting tremor, writer's cramp, impaired vibration sense and brisk deep tendon reflexes have been reported in some patients.[orpha.net]

  • Autosomal Recessive Spinocerebellar Ataxia Type 17

    The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome,[books.google.com] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] MalaCards based summary : Spinocerebellar Ataxia, Autosomal Recessive 17, is also known as scar17 , and has symptoms including tremor and ataxia, truncal .[malacards.org]

  • Autosomal Recessive Spinocerebellar Ataxia 8

    tremor. 10.[slideshare.net] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Tremor in SCA-12 might respond to medications used for essential tremor. SCA12 is caused by a repeat expansion.[ataxiacenter.umn.edu]

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    […] advisory boards of national foundations including the Worldwide Education and Awareness for Movement Disorders (WE MOVE), Dystonia Medical Research Foundation, International Tremor[books.google.com] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] X-linked ataxia Fragile X associated Tremor-Ataxia syndrome (FXTAS) Major Diagnostic criteria:  Onset 50 years, M F  Neurologic: Gait ataxia, tremor, parkinsonism, cognitive[slideshare.net]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    A tremor may appear in a patient with peripheral neuropathy - neuropathic tremor (NT).[news-medical.net] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Polyneuropathy was found in 97.5% of AOA2 patients, cerebellar atrophy in 96%, occasional oculomotor apraxia in 51%, pyramidal signs in 20.5%, head tremor in 14%, dystonia[lib.ugent.be]

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