Onset of Dysarthria in Third Decade of Life & Vertigo: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Onset of Dysarthria in Third Decade of Life, Vertigo,

Negated

None

Unsure

None

Possible Causes

Episodic Ataxia

[…] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia [emedicine.com]

Preliminary findings demonstrate that migrainous vertigo is genetically heterogeneous and complex. [ncbi.nlm.nih.gov]

Vestibular ataxia, vertigo, tinnitus, and interictal myokymia are prominent; attacks are diminished by acetazolamide. [ncbi.nlm.nih.gov]

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Spinocerebellar Ataxia Type 1

During these episodes, many people also experience dizziness (vertigo), nausea and vomiting, migraine headaches, blurred or double vision, slurred speech, and ringing in the [diseaseinfosearch.org]

[…] episodic ataxia may experience: problems with balance and co-ordination slurred, slow and unclear speech (dysarthria) muscle spasms involuntary eye movements (nystagmus) vertigo [nhs.uk]

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Spinocerebellar Ataxia Type 6

Symptoms of vertigo were defined using a structured questionnaire. [ncbi.nlm.nih.gov]

PEDIGREE 3 The proband, age 65, recalled having positional vertigo dating back to his late teens. [jnnp.bmj.com]

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Ataxia

EA-1 is without vertigo, while EA-2 has vertigo. EA-1 is due to mutations in a potassium channel gene KCNA1 on 12p13. [dizziness-and-balance.com]

Benign Paroxysmal Vertigo Benign paroxysmal vertigo (BPV) must be differentiated from benign paroxysmal positional vertigo, which is the most common cause of vertigo in adults [healio.com]

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Cerebellar Ataxia with Peripheral Neuropathy Type 2

Vertigo, dizziness, and imbalance rank amongst the most common presenting symptoms in neurology, ENT, geriatric medicine, and general practice. [books.google.com]

Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6. J Neurol. 2009;256(1):78-82. Asanuma C, Thach WT, Jones EG. [tinnitusjournal.com]

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X-Linked Spinocerebellar Ataxia Type 5

Vertigo, dizziness, and imbalance rank amongst the most common presenting symptoms in neurology, ENT, geriatric medicine, and general practice. [books.google.com]

The crisis starts with vertigo and ataxia, and is often associated with involuntary eye movements. [encyclopedia.com]

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Spinocerebellar Ataxia Type 19

Vertigo, dizziness, and imbalance rank amongst the most common presenting symptoms in neurology, ENT, geriatric medicine, and general practice. [books.google.com]

Patients with SCA6 occasionally manifest episodic ataxia or episodic vertigo. Diplopia occurs in about 50% of patients. [ataxia.uchicago.edu]

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Spastic Ataxia with Congenital Miosis

Inherited periodic ataxia, dysarthria, nystagmus and vertigo. [patient.info]

[…] the third to fourth decade of life. [findzebra.com]

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Autosomal Recessive Spinocerebellar Ataxia 8

EA-1 is without vertigo, while EA-2 has vertigo. [tchain.com]

EA2 Unknown 3-52 Lifelong Nystagmus; attacks last minutes to hours; posture change induced; vertigo; later permanent ataxia 63. [slideshare.net]

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Autosomal Recessive Spinocerebellar Ataxia Type 17

The crisis starts with vertigo and ataxia, and is often associated with involuntary eye movements. [encyclopedia.com]

[…] characteristic symptoms including: frequent falls due to poor balance imprecise hand coordination postural or kinetic tremor of extremities or trunk dysarthria dysphasia vertigo [ipfs.io]

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Autosomal Dominant Spastic Ataxia Type 1

During these episodes, many people also experience dizziness (vertigo), nausea and vomiting, migraine headaches, blurred or double vision, slurred speech, and ringing in the [diseaseinfosearch.org]

Episodic ataxia type 2 (EA2) is characterized by paroxysmal attacks of ataxia, vertigo, and nausea typically lasting minutes to days in duration. [lacaf.org]

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Adult-Onset Autosomal Recessive Cerebellar Ataxia

[…] characteristic symptoms including: frequent falls due to poor balance imprecise hand coordination postural or kinetic tremor of extremities or trunk dysarthria dysphasia vertigo [en.wikipedia.org]

[…] complains of vertigo rather than imbalance 9. [slideshare.net]

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Spinocerebellar Ataxia Type 20

Vertigo: illusionary feeling of head movement a. Types (i) Central Vertigo – brainstem or cerebellar (ii) Peripheral Vertigo – ear canal or inner ear b. [neurosurgerystudent.blogspot.com]

Accordingly, gait analysis can provide useful information on the path physiological status of patients with vertigo. [austinpublishinggroup.com]

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Spinocerebellar Ataxia Type 5

The onset of symptoms is usually in the third or fourth decade of life; however, more subtle clinical manifestations can start in early childhood. [ncbi.nlm.nih.gov]

Keep us informed xx Hi bevvick thank you for all you say it is helpful to me..my mum was diagnosed with vertigo for years and about 4 years ago she got diagnosed with sca6 [healthunlocked.com]

Episodic ataxia type 2 (EA2) is characterized by paroxysmal attacks of ataxia, vertigo, and nausea typically lasting minutes to days in duration. [lacaf.org]

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Spinocerebellar Ataxia Type 4

PEDIGREE 3 The proband, age 65, recalled having positional vertigo dating back to his late teens. [jnnp.bmj.com]

Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6. J Neurol. 2009;256(1):78-82. Asanuma C, Thach WT, Jones EG. [tinnitusjournal.com]

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Spinocerebellar Ataxia Type 12

He is currently part of the Interdisciplinary Center for Vertigo & Balance Disorders at the University Hospital Zurich. [books.google.com]

Yabe I, Sasaki H, Takeichi N, Takei A, Hamada T, et al. (2003) Positional vertigo and macroscopic downbeat positioning nystagmus in spinocerebellar ataxia type 6 (SCA6). [omicsonline.org]

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Autosomal Recessive Spinocerebellar Ataxia

[…] the following problems: Blurred vision and other eye issues Nausea and vomiting Problems standing and sitting Staggering when you walk Trouble walking in a straight line Vertigo [webmd.com]

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Spinocerebellar Ataxia Type 30

Episodic ataxia type 2 (EA2) is characterized by paroxysmal attacks of ataxia, vertigo, and nausea typically lasting minutes to days in duration. [lacaf.org]

You might have dizziness (vertigo), fatigue and muscle weakness during your episodes. In some cases, symptoms resolve in later life. [mayoclinic.org]

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Spinocerebellar Ataxia with Axonal Neuropathy

[…] the following problems: Blurred vision and other eye issues Nausea and vomiting Problems standing and sitting Staggering when you walk Trouble walking in a straight line Vertigo [webmd.com]

EA2 Unknown 3-52 Lifelong Nystagmus; attacks last minutes to hours; posture change induced; vertigo; later permanent ataxia 63. [slideshare.net]

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Infantile-Onset Autosomal Recessive Nonprogressive Cerebellar Ataxia

[…] complains of vertigo rather than imbalance 9. [slideshare.net]

PICA infarct that spares the medulla presents with limb and gait ataxia with acute-onset vertigo, nausea and vomiting. [jpgmonline.com]

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Spinocerebellar Ataxia Type 23

Double vision, dysarthria, impaired hand writing, and episodic vertigo preceded ataxia in 4% of patients, respectively. [real.mtak.hu]

None of the patients had neurological signs other than cerebellar ataxia (except for mild frontal executive dysfunction and mild positional vertigo, both reported in CCA [ [e-jmd.org]

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Optic Atrophy

(3) onset of progressive motor and sensory axonal neuropathy in late childhood/early adolescence; (4) dysarthria starting in the third decade of life; (5) exacerbated acoustic [ncbi.nlm.nih.gov]

Other symptoms such as vertigo may be due to proximity of the oculomotor area to the equilibrium area. [medicaljoyworks.com]

Specific symptoms include blurred vision, acuity, impaired color vision, photophobia, headaches and vertigo. [symptoma.com]

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Autosomal Recessive Spastic Ataxia with Leukoencephalopathy

EA2 Unknown 3-52 Lifelong Nystagmus; attacks last minutes to hours; posture change induced; vertigo; later permanent ataxia 63. [slideshare.net]

see Ménière disease AUH defect, see 3-methylglutaconyl-CoA hydratase deficiency aural vertigo, see Ménière disease auricular fibrillation, see familial atrial fibrillation [mygenomics.com]

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Spinocerebellar Ataxia Type 13

Double vision, dysarthria, impaired hand writing, and episodic vertigo preceded ataxia in 4% of patients, respectively. [real.mtak.hu]

[…] episodic ataxia may experience: problems with balance and co-ordination slurred, slow and unclear speech (dysarthria) muscle spasms involuntary eye movements (nystagmus) vertigo [nhs.uk]

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Vestibulocerebellar Ataxia

Vertigo must be distinguished from nonvertiginous dizziness, which includes sensations of light-headedness, faintness, or giddiness not associated with an illusion of movement [accessmedicine.mhmedical.com]

Such disorders usually present with one of two clinical problems: vertigo or ataxia. VERTIGO Vertigo is the illusion of movement of the body or the environment. [neupsykey.com]

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Spinocerebellar Ataxia with Rigidity and Peripheral Neuropathy

Gait characteristics of patients with phobic postural vertigo: effects of fear of falling, attention, and visual input, J Neurol 261(4) (2014), 738–746. [31] R. [epub.ub.uni-muenchen.de]

Diseases & Conditions Benign positional vertigo Benign positional vertigo is the most common type of vertigo. [mountsinai.org]

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Autosomal Dominant Sensory Ataxia

[…] appear ONLY on closure of the eyes) - hyporeflexia of the legs (prominent in tabes dorsalis and polyneuropathies that cause sensory ataxia) - nystagmus or dysarthria or vertigo [quizlet.com]

’ peripheral vestibular causes See ‘vertigo’ central vestibular causes Causes of cerebellar ataxia: Acute: Vertebrobasilar ischemia and infarction Cerebellar hemorrhage Drugs [learningneurology.com]

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Spinocerebellar Ataxia Type 22

Vertigo, dizziness, and imbalance rank amongst the most common presenting symptoms in neurology, ENT, geriatric medicine, and general practice. [books.google.com]

Another case was a 75-year-old Japanese male suffered from unsteadiness of gait, ataxia of gait and stance and positional vertigo. [ashg.org]

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Autosomal Recessive Spinocerebellar Ataxia 3

EA2 Unknown 3-52 Lifelong Nystagmus; attacks last minutes to hours; posture change induced; vertigo; later permanent ataxia 63. [slideshare.net]

The crisis starts with vertigo and ataxia, and is often associated with involuntary eye movements. [encyclopedia.com]

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Early-Onset Spastic Ataxia - Neuropathy Syndrome

Inherited periodic ataxia, dysarthria, nystagmus and vertigo. [patient.info]

[…] episodic ataxia may experience: problems with balance and co-ordination slurred, slow and unclear speech (dysarthria) muscle spasms involuntary eye movements (nystagmus) vertigo [nhs.uk]

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