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165 Possible Causes for Onset of Dysarthria in Third Decade of Life, Vibratory Sensation Decreased

  • Spinocerebellar Ataxia Type 1

    […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.com] sensation Decreased vibration sense Decreased vibratory sense Diminished vibratory sense Impaired vibratory sense [ more ] 0002495 Limb ataxia 0002070 Muscular hypotonia[rarediseases.info.nih.gov] […] nystagmus, limb spasticity, limb and gait ataxia, and diminished vibration perception Progression generally slow Spinocerebellar ataxia 10 See the list below: Clinical features Onset[emedicine.com]

  • Spinocerebellar Ataxia Type 5

    The onset of symptoms is usually in the third or fourth decade of life; however, more subtle clinical manifestations can start in early childhood.[ncbi.nlm.nih.gov] They are characterized by progressive cerebellar ataxia resulting in unsteady gait, clumsiness, dysarthria, and swallowing difficulty.[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Pernicious Anemia

    Autoimmun Rev. 2014 Apr-May;13(4-5):565-8. doi: 10.1016/j.autrev.2014.01.042. Epub 2014 Jan 11. Author information 1 Laboratory of Clinical Pathology, San Antonio Hospital, via Morgagni 18, 33028 Tolmezzo, UD, Italy. Electronic address: nicola.bizzaro@ass3.sanita.fvg.it. 2 Laboratory of Clinical Pathology, Civic Hospital, via[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Subacute Combined Degeneration of Spinal Cord

    Posterior column dysfunction decreases vibratory sensation and proprioception (joint sense).[en.wikipedia.org]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Multifocal Motor Neuropathy

    Abstract Multifocal motor neuropathy with conduction block (MMNcb) is a relatively rare disease characterized clinically by asymmetric limb weakness with spared sensation and electrophysiologically by persistent focal motor conduction block. We present the case of a 40-year-old male patient with six-year history of[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Multiple Sclerosis

    J Neurol Neurosurg Psychiatry. 1987 May; 50(5): 523–531. This article has been cited by other articles in PMC. Abstract The mean survival period in a series of 216 multiple sclerosis deaths, which formed part of a large prevalence sample observed in the Grampian region of Scotland, was 24.5 years, with an[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Machado-Joseph Disease

    We describe three patients with the Machado-Joseph disease (MJD) genetic abnormality who had non-movement disorder neurological symptoms or signs that preceded the gait ataxia by several years. This implies that some clinical manifestations other than ataxia may be considered part of the herald symptoms of MJD,[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Spinal Cord Compression

    South Med J. 2017 Sep;110(9):586-593. doi: 10.14423/SMJ.0000000000000700. Author information 1 From the Departments of Internal Medicine, Radiation Oncology, and Neurosurgery, Augusta University, Augusta, Georgia, the Dattoli Cancer Center, Sarasota, Florida, the Department of Radiation Oncology, University of Alabama[…][ncbi.nlm.nih.gov]

    Missing: Onset of Dysarthria in Third Decade of Life
  • Friedreich Ataxia

    A few days before the International Rare Disease Day - which is celebrated annually on the last day of February - the prestigious journal "Cell Reports" has published the work of researchers of Fratagene Therapeutics, led by Dr. Alessandra Rufini, on the identification of a significant new therapeutic target for[…][curefa.org]

    Missing: Onset of Dysarthria in Third Decade of Life

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