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2 Possible Causes for Onset of Proteinuria in Third to Fourth Decade of Life

  • Lipoid Nephrosis

    More than 90% of pediatric cases arise on the grounds of MCD, while 10-15% of adult cases, in whom the diagnosis is most frequently made in the third and fourth decades of[symptoma.com] The principal feature of lipoid nephrosis is the sudden onset of proteinuria accompanied by edema in a previously healthy individual, with urine protein levels reaching as[symptoma.com] life, occurs due to MCD.[symptoma.com]

  • Nephrotic Syndrome Type 9

    Dominant mutations in ACTN4, TRPC6, and INF2 are associated with late-onset proteinuria and progress to ESRD during the third and fourth decades of life 13, 14, 17, 37).[ncbi.nlm.nih.gov]

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