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2,591 Possible Causes for Onset of Symptoms in First or Second Decade of Life, Patient Appears Chronically Ill, Psychomotor Retardation

  • Tay-Sachs Disease

    Late-onset Tay-Sachs disease (chronic form) is a rare variant phenotype with appearance of first symptoms during the second or third decade of life. 4 A juvenile form is also[doi.org] The patients was a 3-year-old boy with psychomotor retardation and attacked by seizures since 8 months of age. On funduscopy, the maculla presented a cherry-red spot.[ncbi.nlm.nih.gov] Psychomotor retardation appears after the age of 8 months with hypotonia, amaurosis, and megalencephaly. A cherry-red macular spot may be found but is not specific.[orpha.net]

  • Chronic Fatigue Syndrome

    Consistently reported risk factors for poor prognosis are older age, more chronic illness, having a comorbid psychiatric disorder and holding a belief that the illness is[ncbi.nlm.nih.gov] We hypothesize that IFNγ-mediated lesions in kynurenine metabolism may culminate in the depression and psychomotor retardation that contribute to disability in some patients[dx.doi.org] Some typical sickness behavior symptoms, such as psychomotor retardation, anorexia and weight loss do not occur in ME/CFS unless there is comorbid depression.[doi.org]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Suicidal Depression

    Although depression is common in any chronic illness, it is more prevalent with Lyme patients than in most other chronic illnesses.[mentalhealthandillness.com] Signs of depression may include the following: Psychomotor retardation or agitation, such as slowed speech, sighs, and long pauses Slowed body movements, even to the extent[emedicine.medscape.com] There appears to be multiple causes, including a number of psychological and physical fac tors.[mentalhealthandillness.com]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Aspiration Pneumonia

    We present the case of a 4-month-old infant from the Foster Care Center, with severe psychomotor retardation, blindness, and associated cardiac malformation, who was admitted[ncbi.nlm.nih.gov]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Lupus Encephalitis

    The patient presented with fluctuating mentation, fatigue, psychomotor retardation, anorexia (with 16 lbs of weight loss), dysarthria with word-finding difficulty, slow speech[healio.com]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Anorexia Nervosa

    retardation, especially in the later stages of the disease.[emedicine.medscape.com] […] insulin clearance) Low parathyroid hormone levels Elevated liver function Low white blood cell (WBC) count Behaviorally, a patient may demonstrate a flat affect and display psychomotor[emedicine.medscape.com]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Brain Abscess

    Clinically speaking, he presents a height-weight hypertrophia, vitamin D loss rickets, and psychomotor retardation.[ncbi.nlm.nih.gov]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Multiple Sclerosis

    Another complicating factor is that many of the symptoms of depression are confounded with MS (e.g. fatigue, psychomotor agitation or retardation, changes in sleep patterns[doi.org]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Cerebral Arteriosclerosis

    A differing profile of symptoms due to subcortical ischemic changes, described as “disconnection syndrome”, including psychomotor retardation, difficulty at work, apathy,[bmcpsychiatry.biomedcentral.com]

    Missing: Onset of Symptoms in First or Second Decade of Life
  • Hallervorden-Spatz Syndrome

    There is an early onset classic form with symptoms of extrapyramidal disease beginning in the first decade of life and rapid progression to loss of ambulation in about 15[disorders.eyes.arizona.edu] Others with atypical disease may not have symptoms until the second or third decades.[disorders.eyes.arizona.edu]

    Missing: Patient Appears Chronically Ill

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