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2,136 Possible Causes for Onset of Symptoms in the Fourth to Sixth Decade of Life, Polyarthritis, Xerostomia

  • Rheumatoid Arthritis

    Sjogren’s syndrome is an autoimmune condition that affects exocrine gland function, leading to a reduction in tear production (keratoconjunctivitis sicca), oral dryness (xerostomia[hopkinsarthritis.org] AITL typically presents with lymphadenopathy, fever, rash, hepatosplenomegaly, and rarely polyarthritis.[ncbi.nlm.nih.gov] Sjögren’s syndrome used in this and other studies, 36, 37 the frequency of the diagnosis depends heavily on the availability of specific tests for the evaluation of possible xerostomia[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Hemochromatosis

    This may manifest as a polyarthritis and can result in sudden gout-like attacks, termed "Pseudo-gout".[pathwaymedicine.org] […] observed intermittent arthritis leading to misdiagnosis of rheumatoid arthritis. 5 Rheumatoid arthritis (RA) is a symmetric, progressive, autoimmune, chronic inflammatory polyarthritis[scielo.br]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Amyloidosis

    Areas of swelling, hemorrhages under the skin (purpura), hair loss (alopecia), inflammation of the tongue (glossitis) and a dry mouth (xerostomia) may also be present.[rarediseases.org] A 64-year-old man on hemodialysis for 30 years was admitted because of intermittent fever, polyarthritis, and elevated serum C-reactive protein (CRP) level, which was continuous[ncbi.nlm.nih.gov] It is usually “secondary” to a chronic inflammatory condition, such as rheumatoid arthritis, juvenile chronic polyarthritis, ankylosing spondylitis, inflammatory bowel disease[archivesofpathology.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Diffuse Scleroderma

    Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206 Skin ulcer Open skin sore 0200042 Telangiectasia of the skin 0100585 Xerostomia[rarediseases.info.nih.gov]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Sjögren Syndrome

    Sjogren's syndrome, involving sicca symptoms with xerostomia, stomatitis, and considerable pain is a difficult-to-treat autoimmune disease where the treatment options are[ncbi.nlm.nih.gov] Case 2: Female, 10 years old, reporting recurrent parotitis for 1 year and polyarthritis for 10 days.[ncbi.nlm.nih.gov] […] patients) M: 60 F: 487 51 M: 5 F: 46 Cardiovascular diseases (27) Non-haematological malignancies (13) At diagnosis or developing during follow-up, old age at diagnosis, polyarthritis[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Polyarthritis

    Two patients also developed xerostomia and xerostomia, and laboratory test results showed normal values of CRP and erythrocyte sedimentation rate.[ncbi.nlm.nih.gov] Only in case of generalized disease, polyarthritis may develop.[symptoma.com] This condition is termed alphavirus polyarthritis syndrome.[en.wikipedia.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Sarcoidosis

    […] is the most frequent cause of sarcoidosis-related death Bone 5% Osteolytic or cystic lesions Osteopenia Oral 5% Asymptomatic parotid swelling (most common) Parotitis with xerostomia[merckmanuals.com] […] a fever, from Ohio, zoo keeper histoplasmosis Old guy in his 60's works on ceramics Berylliosis " Other manifestations include hepatic granulomas, granulomatous uveitis, polyarthritis[smartypance.com] Loefgren syndrome Löfgren syndrome is classically described as a triad of EN, polyarthritis, and hilar adenopathy.[emedicine.medscape.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Carcinomatous Polyarthritis

    […] exocrinopathy, is characterized by a benign lymphocytic infiltrate of salivary and lacrimal glands that leads to the development of sicca syndrome (keratoconjunctivitis and xerostomia[musculoskeletalkey.com] Polyarthritis resembling rheumatoid arthritis (RA) may be the presenting manifestation of occult malignancy.[ncbi.nlm.nih.gov] […] carcinomatous polyarthritis asymmetric arthritis of the large and small joints, often in association with malignancy.[medicine.academic.ru]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Inflammatory Bowel Disease Type 1

    […] needles feeling Tingling [ more ] 0003401 Protein-losing enteropathy 0002243 Sporadic No previous family history 0003745 Thromboembolism 0001907 Vomiting Throwing up 0002013 Xerostomia[rarediseases.info.nih.gov] We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disease associated spondyloarthritis.[ncbi.nlm.nih.gov] The most common presenting symptoms include hypogeusia (40.9%), diarrhea (35.4%), abdominal discomfort (9.1%), alopecia (8.2%), and xerostomia (6.4%) [3, 5].[hindawi.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Mixed Connective Tissue Disease

    Xerostomia (dry mouth due to decreased saliva). Low-grade fever (usually under 100 F). Photosensitivity (development of rashes or other symptoms after sun exposure).[hss.edu] She had polyarthritis, edematous fingers with Raynaud's phenomenon, sicca syndrome, interstitial lung disease, possible myositis, and was positive for anti-nuclear antibody[ncbi.nlm.nih.gov] Main symptoms of the disease are polyarthritis, hand oedema, Raynaud's phenomenon, sclerodactyly, myositis and oesophageal hypomobility.[ncbi.nlm.nih.gov]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life

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