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13 Possible Causes for Optic Atrophy - Chronic Phase, Optic Disc Pallor

  • Leber's Hereditary Optic Neuropathy

    Chronic phase The retinal nerve fibre layer gradually degenerates and after six months optic atrophy is a universal feature of LHON. 30 If a patient is only seen at this stage[jmg.bmj.com] Fundoscopic examination showed hyperemic papilla on the right eye and optic disc pallor on the left eye.[ncbi.nlm.nih.gov] After subsequent development of bilateral optic disc pallor, we concluded that the patient had LHON. mtDNA analysis was conducted using non-radioisotopic single-strand conformational[ncbi.nlm.nih.gov]

  • Optic Atrophy

    OCTA allows the detection of previous microvascular abnormalities in the chronic phase.[ncbi.nlm.nih.gov] CONCLUSIONS: Deeply buried ODD may be associated with NAION causing irreversible visual loss and optic disc pallor, a condition easily mistaken for atypical ON.[ncbi.nlm.nih.gov] […] field defects and optic disc pallor.[ncbi.nlm.nih.gov]

  • Secondary Optic Atrophy

    This acute phase consolidates in a chronic state in about one year after the onset of visual loss, leaving the patients with optic atrophy and usually permanent blindness[journals.plos.org] Differential Diagnosis Optic atrophy versus other causes of optic disc pallor: • Pallor of optic disc in partial optic atrophy must be differentiated from other causes of[slideshare.net] disc pallor seen in advanced glaucoma is due to a more excavated cup rather than pallor of the neuroretinal rim Temporal Optic Disc Pallor May be observed in traumatic or[decisionmakerplus.net]

  • Central Retinal Artery Occlusion

    Optical coherence tomography (OCT) of the macula of the chronic phase of central retinal artery occlusion of the right eye indicated loss of the normal foveal depression,[ncbi.nlm.nih.gov] Within 4 to 6 weeks, the retinal whitening usually resolves and optic disc pallor sets in.[mjdrdypu.org] A fundus examination of the left eye found a pink optic disc with blurred margins, diffuse pallor in the retina with arterial attenuation, and a normal band of the retinal[ncbi.nlm.nih.gov]

  • Optic Neuropathy

    Optic neuropathy associated with primary Sjögren's syndrome may show variable clinical courses, including acute optic neuritis, insidious progression of chronic optic atrophy[ncbi.nlm.nih.gov] , and (f) development of optic disc pallor, usually within 6-8 weeks.[webeye.ophth.uiowa.edu] Chronic phase The retinal nerve fibre layer gradually degenerates and after six months optic atrophy is a universal feature of LHON. 30 If a patient is only seen at this stage[jmg.bmj.com]

  • Hereditary Optic Atrophy

    Chronic phase The retinal nerve fibre layer gradually degenerates and after six months optic atrophy is a universal feature of LHON. 30 If a patient is only seen at this stage[jmg.bmj.com] There was bilateral optic disc pallor in fundoscopy and his visual accurate was diminished to counting fingers from one meter.[omicsonline.org] This acute phase consolidates in a chronic state in about one year after the onset of visual loss, leaving the patients with optic atrophy and usually permanent blindness[journals.plos.org]

  • Neuromyelitis Optica

    In chronic stages, atrophy of the optic nerves and variable hyperintensity on T2-weighted images are frequently observed ( 5, 35, 38, 40, 41 ).[pubs.rsna.org] Two patients who presented with clinical optic neuritis also had abnormal VEPs and optic disc pallor.[archneur.ama-assn.org] During the acute and subacute phases, optic neuritis is usually identified as a thickened optic nerve with hyperintensity on T2-weighted images and enhancement on gadolinium-enhanced[pubs.rsna.org]

  • Congenital Optic Disc Coloboma

    […] nerve looks completely unremarkable. 7 In the chronic phase, the nerve fiber layer degenerates, which causes optic atrophy. 7 The acute phase typically persists for four[reviewofoptometry.com] The fundus examination revealed an increased cup-to-disc ratio with pallor on the left disc and a normal optic nerve on the right (See Figure 4A).[reviewofophthalmology.com] They include optic nerve pallor or atrophy, [2] poor macular reflex and foveal hypoplasia, [2] tilted optic discs, [3] optic nerve hypoplasia, [3] optic nerve coloboma, [3[ojoonline.org]

  • Coloboma of Optic Papilla

    […] nerve looks completely unremarkable. 7 In the chronic phase, the nerve fiber layer degenerates, which causes optic atrophy. 7 The acute phase typically persists for four[reviewofoptometry.com] optic atrophy Inclusion term(s): Temporal pallor of optic disc H47.291 Other optic atrophy, right eye H47.292 Other optic atrophy, left eye H47.293 Other optic atrophy, bilateral[icd10coded.com] Optic Atrophy Observed clinically as pallor of the disc PRIMARY - disc margins are distinct SECONDARY - disc margins indistinct - such cases result from previous oedema or[academy.org.uk]

  • Renal Coloboma Syndrome

    […] nerve looks completely unremarkable. 7 In the chronic phase, the nerve fiber layer degenerates, which causes optic atrophy. 7 The acute phase typically persists for four[reviewofoptometry.com] Optic nerve appearance following AION, which features disc pallor located more temporally than nasally. • Papilledema is defined as disc swelling secondary to increased intracranial[reviewofoptometry.com] Then, after approximately six months, patients transition into the chronic phase. 7 Patients with Leber’s hereditary optic neuropathy characteristically experience significant[reviewofoptometry.com]

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