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109 Possible Causes for Optic Disc Pallor, Secondary Optic Atrophy

  • Foster-Kennedy Syndrome

    History Progressive loss of vision in one eye secondary to compressive optic atrophy Optic atrophy is a result of axon compression or ischemia secondary to vascular compression[eyewiki.aao.org] The original description of the Foster Kennedy syndrome included the clinical triad of optic disc pallor in one eye, optic disc edema in the other eye, and reduced olfaction[ncbi.nlm.nih.gov] An 11-year-old boy with a juvenile nasopharyngeal angiofibroma developed optic disc pallor in one eye and optic disc edema in the other eye (Foster Kennedy Syndrome [FKS])[ncbi.nlm.nih.gov]

  • Leber's Hereditary Optic Neuropathy

    We report a 12-year-old girl who presented with reduced visual acuity secondary to optic atrophy at 8 months of age, which led to a clinical diagnosis of LHON.[ncbi.nlm.nih.gov] Fundoscopic examination showed hyperemic papilla on the right eye and optic disc pallor on the left eye.[ncbi.nlm.nih.gov] There was no family history of optic atrophy in three of the four patients.[ncbi.nlm.nih.gov]

  • Primary Optic Atrophy

    Out of 42% non-glaucomatous optic atrophy, 55% manifested primary optic atrophy, 38% secondary optic atrophy and 7% consecutive optic atrophy.[nepjol.info] Optic disc pallor is one of the defining characteristics of Dominant Optic Atropy.[webeye.ophth.uiowa.edu] The disease manifested as primary optic atrophy in 48 patients, as secondary optic atrophy due to papilloedema in 15 cases and due to papillitis in 26 cases. 11 cases had[ijo.in]

  • Optic Atrophy

    Late presentation of craniosynostosis and the pathophysiology of secondary optic atrophy are discussed.[ncbi.nlm.nih.gov] CONCLUSIONS: Deeply buried ODD may be associated with NAION causing irreversible visual loss and optic disc pallor, a condition easily mistaken for atypical ON.[ncbi.nlm.nih.gov] Secondary optic atrophy In conditions with secondary optic atrophy (eg, papilledema, papillitis), the atrophy is secondary to papilledema (shown in the image below).[emedicine.medscape.com]

  • Globoid Cell Leukodystrophy

    Signs included pes cavus, optic disc pallor, progressive spastic tetraparesis, a sensorimotor demyelinating neuropathy and hypodense lesions in the parieto-occipital periventricular[ncbi.nlm.nih.gov]

  • Idiopathic Intracranial Hypertension

    Meanwhile, all children regardless of age or ability to cooperate need careful neurological and ophthalmic follow up with the aim of preventing secondary optic atrophy.[dx.doi.org] pallor in the presence of continuing swelling 24, 25 (Fig. 3 ).[doi.org] However, more typically, peripheral field and central acuity are only lost in longer standing cases as a result of axonal death (secondary optic atrophy).[doi.org]

  • Multiple Sclerosis

    The evolution of temporal optic disc pallor (arrow) after left optic neuritis.[emedicine.com] At that time, symptoms and signs of right-sided sensory disturbance together with a history of uniocular central visual loss and, on fundoscopy, pallor of both optic discs[medicalcannabis.it] During this time, patients develop optic atrophy, with temporal optic disc pallor (see image below).[emedicine.com]

  • Behr Syndrome

    Optic atrophy is the dysfunction of the optic nerve which results in impaired vision. These are secondary conditions that the disease has caused.[medigest.uk] Certain disc appearances can help to determine the cause for the optic nerve damage. Sector disc pallor in an older individual could have been caused by NAION.[eyewiki.aao.org] Acuity in the first decade is in the 20/70 to 20/100 range with little worsening in patients followed for a decade or more even though the disc pallor may increase with loss[disorders.eyes.arizona.edu]

  • Cockayne Syndrome

    Ocular examination showed hazy cornea, stromal opacities, optic disc pallor, and subpolar cataract.[ijpd.in] Ocular findings include pigmentary retinal degeneration with a characteristic“salt and pepper” appearance of retina, cataracts, optic nerve atrophy, optic disc pallor, iris[ijpd.in]

  • Methanol Poisoning

    Other diagnostic clues are ophthalmic changes and may include hyperemia of the optic disc or optic disc edema, and eventually, pallor (Jacobsen 1997).[web.archive.org]

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