Oral Mucosal Disorder & Toxic Plant: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Oral Mucosal Disorder, Toxic Plant,

Negated

None

Unsure

None

Possible Causes

Philodendron Poisoning

The severity of poisoning and time until onset of symptoms is proportional to the amount of plant ingested. The plant is most toxic in the spring. [clinicalgate.com]

DO NOT touch or eat any plant with which you are not familiar. Wash your hands after working in the garden or walking in the woods. Graeme KA. Toxic plant ingestions. [medlineplus.gov]

Toxic plant ingestions. In: Auerbach PS, Cushing TA, Harris NS, eds. Auerbach's Wilderness Medicine. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 65. Lim CS, Aks SE. [limamemorial.org]

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Dieffenbachia Poisoning

There are hundreds, otherwise thousands, of toxic plants worldwide, and also several of them are fatal. [pinterest.ch]

Toxic plant ingestions. In: Auerbach PS, Cushing TA, Harris NS, eds. Auerbach's Wilderness Medicine. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 65. Lim CS, Aks SE. [medlineplus.gov]

Plant-induced dermatitis. In: Auerbach PS, ed. Wilderness Medicine. 6th ed. Philadelphia, Pa: Mosby Elsevier; 2011:chap 63. Graeme, KA. Toxic plant ingestions. [salud.wikiplus.org]

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Cannabis Abuse

Abdominal pain (upper), oral mucosal discolouration, oral mucosal disorder, oral mucosal exfoliation, stomatitis, tooth discolouration. Application site irritation. [patient.info]

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Dermatitis

It's lovely blooms, leaves, and the whole plant are highly toxic. [brodericks.net]

How does a disorder that damages the intestines show up on the skin? [celiac.org]

Such substances are toxic to the skin and are termed primary irritants. [emedicinehealth.com]

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Umbilical Sepsis

October 21, 2019: BMC Research Notes #363 Yigizie Yeshaw, Muluken Fekadie Zerihun OBJECTIVES: Khat is an herbal cultivated plant growing mainly in Eastern Africa and Arabians [read.qxmd.com]

hiatus hernia, irritable bowel syndrome, oral mucosal petechiae, salivary hypersecretion, tongue coated, tongue discolouration, faecal impaction. [mymemory.translated.net]

Chronic khat chewing leads to the development of liver toxicity, cardiovascular disease, sleeping disorder, psychosis, memory impairment, poor academic performance and variety [read.qxmd.com]

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Halitosis

In 2005, Brazilian researchers tested orally unhealthy saliva samples against various plant extracts. [globalhealingcenter.com]

Oral medicine doctors provide comprehensive care for mucosal diseases, salivary gland disorders, orofacial pain conditions, and oral complications of cancer therapies, among [health.harvard.edu]

Sage and clove were observed to be among the most toxic to harmful organisms that cause bad breath and detract from oral health. [ 1 ] A similar effect was noticed in 2008 [globalhealingcenter.com]

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Chemical Burn

Although protoanemonin, which is considered as the main toxic substance, was reported to be absent in dried or boiled plants, the plant was boiled, cooled, and wrapped over [ncbi.nlm.nih.gov]

Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders. [eyewiki.aao.org]

People and workers who may be exposed to toxic chemicals include: Construction workers Industrial workers (manufacturing plants) Cleaners and cleaning crews Medical staff [kmtrial.com]

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Oral Leukoplakia

Tea tree oil may be toxic when taken by mouth and therefore, should not be swallowed. [livingnaturally.com]

PMID 16316774 Malignant transformation in 1458 patients with potentially malignant oral mucosal disorders: a follow-up study based in a Taiwanese hospital. [atlasgeneticsoncology.org]

MathewAl, pai KM. the prevalance of oral mucosal lesion in patients visiting a dental school in southern india. Indian j dent res. 2008;19;99- 103. 5. Waal IVD. [slideshare.net]

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Congenital Malabsorption of Folic Acid

Homocysteine is a toxic metabolite; therefore humans neutralize it normally as soon as possible. [mdpi.com]

There can be leukopenia and thrombocytopenia, diarrhea and/or oral mucositis, hypoimmunoglobulinemia, and other immunologic dysfunction resulting in infections, most often [ncbi.nlm.nih.gov]

When meat, fish or plant proteins are digested, amino acids are released, among these is methionine, which is converted to homocysteine. [mdpi.com]

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Radiation Stomatitis

Tea tree oil may be toxic when taken by mouth and therefore, should not be swallowed. [livingnaturally.com]

• Soft tissue necrosis • Osteoradionecrosis The patient is at risk of developing significant oral sequelae during initial phases of the transplant including oral mucositis [dimensionsofdentalhygiene.com]

mucositis (Table 1, Figure 14,15 ). 16 mIAS shares some similarities with aphthous ulcers (also referred to as canker sores), a common oral condition with varied causes related [mdedge.com]

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Toxic Effect of Corrosive Alkalis

pesticides, and other toxic agents. [icdlist.com]

Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders. [eyewiki.aao.org]

[…] on the large quantities of Hg used in paper and chlor-alkali plants. [corrosion-doctors.org]

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Toxic Epidermal Necrolysis

Toxic epidermal necrolysis A review and report of the successful use of Biobrance for nearly wound coverage. Ann plant Burg. 1995;35:124-132. 31. Barillo DJ, Goodwin CW. [ijdvl.com]

Crispian Scully, Mucosal, oral and cutaneous disorders, Scully's Medical Problems in Dentistry, 10.1016/B978-0-7020-5401-3.00011-4, (323-336), (2014). [doi.org]

Porter, Erythema multiforme and related disorders, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 10.1016/j.tripleo.2006.12.008, 103, 5, [doi.org]

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Pachyonychia Congenita

Tea tree oil may be toxic when taken by mouth and therefore, should not be swallowed. [simplygoodnaturalfoods.com]

[…] pachyonychia congenita type 2. 8 Smith FJ...McLean WH 9618173 1998 10 A mutation in the mucosal keratin K4 is associated with oral white sponge nevus. 71 Rugg EL...Munro [malacards.org]

Avoid if allergic to tea tree oil or plants of the Myrtle (Myrtaceae) family, Balsam of Peru, or benzoin. Use cautiously with a history of eczema. [simplygoodnaturalfoods.com]

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Anosmia

plant chemicals. [en.wikipedia.org]

Oral cavity and mucosal disorders including oral infections, inflammation, and radiation-induced mucositis can impair taste sensation. [emedicine.medscape.com]

Treat mucosal disorders (eg, infections, inflammations). Treat oral candidiasis and other local factors, and replete any vitamin deficiency that may cause glossitis. [emedicine.medscape.com]

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Leishmaniasis

The plant was found to be toxic to sand flies and that the life span of flies that ate from this plant was significantly shortened and sometimes led to their premature death [en.wikipedia.org]

The differential diagnosis of oral mucosal leishmaniasis must be established with fungal infections (blastomycosis), syphilis, tuberculosis, leprosy, sarcoidosis, midline [scielo.isciii.es]

[…] before they could spread the disease. [25] [26] Hebrew University study found that some plants attract sand flies. [en.wikipedia.org]

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Multiple Hamartoma Syndrome

Clinical Approach to Regional Dermatoses -- Urticaria and Angioedema -- Figurate Erythemas -- Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Necrolysis Epidermal [worldcat.org]

Autism-spectrum disorder Mental retardation Papillary or follicular variant of papillary thyroid cancer Thyroid structural lesions, such as adenoma, nodule(s), or goiter [cancer.net]

Planus and Lichenoid Dermatoses -- Atopic Dermatitis -- Other Eczematous Eruptions -- Irritant and Allergic Contact Dermatitis, Occupational Dermatoses, and Dermatoses Due to Plants [worldcat.org]

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Loose Anagen Syndrome

The condition can also have other causes like consumption of toxic plants, intoxication with poisonous heavy metals, the loose anagen syndrome or compulsive hair pulling, [elmaskincare.com]

Oral Mucositis Contact Stomatitis Dermatologic Manifestations of Oral Leukoplakia Disorders of Oral Pigmentation Drug-Induced Gingival Hyperplasia Eosinophilic Ulcer Fissured [dokterairlangga.com]

Tongue Geographic Tongue Hairy Leukoplakia Hairy Tongue Melanotic Neuroectodermal Tumor of Infancy Metastatic Neoplasms to the Oral Cavity Mucocele and Ranula Mucosal Candidiasis [dokterairlangga.com]

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Tobacco

We present two cases of rare human poisoning in one family following ingestion of cooked leaves from the tobacco tree plant, Nicotiana glauca. [ncbi.nlm.nih.gov]

Javed F, Chotai M, Mehmood A, Almas K: Oral mucosal disorders associated with habitual gutka usage: a review. [karger.com]

[…] to broad-leaved plants but only marginally toxic to grasses and cereals. [web.archive.org]

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Limbal Stem Cell Deficiency

The milky sap or latex of the Euphorbia plant is highly toxic and an irritant to the skin and eye. [ncbi.nlm.nih.gov]

Midterm results on ocular surface reconstruction using cultivated autologous oral mucosal epithelial transplantation. Am J Ophthalmol. 2006;141:267-275. 12. [crstodayeurope.com]

Long-term results of autologous cultivated oral mucosal epithelial transplantation in the scar phase of severe ocular surface disorders. [dovepress.com]

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Catha Edulis

Graeme, Toxic Plant Ingestions, Wilderness Medicine, 10.1016/B978-0-323-03228-5.50063-X, (1286-1321), (2007). J.M. Moreno Salcedo and J.L. [dx.doi.org]

Nigussie 2013 Khat has been reported to have detrimental effects on dental and oral tissues, including keratotic white lesions, mucosal pigmentations, plasma cell stomatitis [drugs.com]

[…] mechanisms of toxicity. [ncbi.nlm.nih.gov]

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Autosomal Dominant Dyskeratosis Congenita 2

Tea tree oil may be toxic when taken by mouth and therefore, should not be swallowed. [livingnaturally.com]

Dyskeratosis congenita (DC) is a highly heterogeneous disorder characterized by abnormal skin pigmentation, nail dystrophy and oral leukoplakia (mucosal keratosis appearing [dnatesting.uchicago.edu]

Avoid if allergic to tea tree oil or plants of the Myrtle (Myrtaceae) family, Balsam of Peru, or benzoin. Use cautiously with a history of eczema. [livingnaturally.com]

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Pachyonychia Congenita Type 2

Tea tree oil may be toxic when taken by mouth and therefore, should not be swallowed. [ehardts.com]

[…] pachyonychia congenita type 2. 56 Smith FJ...McLean WH 9618173 1998 10 A mutation in the mucosal keratin K4 is associated with oral white sponge nevus. 6 Rugg EL...Munro [malacards.org]

Avoid if allergic to tea tree oil or plants of the Myrtle (Myrtaceae) family, Balsam of Peru, or benzoin. Use cautiously with a history of eczema. [ehardts.com]

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Sirolimus

Since MMF can induce gastrointestinal toxicity, suspected cases of gastrointestinal GVHD had to be proven histologically. [haematologica.org]

Mucosal Disease Due to Graft-versus-host Disease 1 2TerminatedSupportive Care Chronic Myeloproliferative Disorders / Graft Versus Host Disease (GVHD) / Leukemias / Lymphoproliferative [drugbank.ca]

A clinical diagnosis of post-trans-plant thrombotic microangiopathy was established according to previously defined international criteria. 25 Statistical analysis Eight end-points [haematologica.org]

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