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829 Possible Causes for Oral Pigmentation

  • Vitamin B12 Deficiency

    BACKGROUND: The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy. METHODS: Twenty-two patients with vitamin B12 deficiency were included. Patients' chief complaints, oral manifestations, blood examination[…][]

  • Acanthosis Nigricans

    Oral lesions of acanthosis nigricans seldom are pigmented.[]

  • Addison's Disease

    The patient presented with oral pigmented lesions, which were hypothesized to be mucosal pigmentation associated with Addison's disease.[] An eighty-year-old man who had complained of skin pigmentation and weight loss was referred to our hospital.[] Oral melanoacanthoma is a mucocutaneous, pigmented, rare, benign, and probably reactive lesion.[]

  • Fabry Disease

    Fabry disease (MIM 301500) is an X-linked recessive lysosomal storage disorder resulting from deficient α-galactosidase A (α-Gal A) activity. It has been estimated that this disease affects 1 in 50 000 males in the general population. 1,2 α-Gal A is an enzyme involved in the metabolic breakdown of globotriaosylceramide[…][]

  • Peutz-Jeghers Syndrome

    A girl with a positive family history grew oral pigmentation at 1 and got intussusception by small bowel hamartomas at 5.[] Mismatch DNA repair (MMR) mRNA expression analysis was performed on a biopsy of oral mucosa melanin pigmentation lesion, a hamartomatous polyp and peripheral blood derived[] The role of STK 11 gene testing in individuals with oral pigmentation. Australas J Dermatol. 2017 May;58(2):135-138. doi: 10.1111/ajd.12443. Epub 2016 Jan 14.[]

  • Cachexia

    Diabetic neuropathic cachexia is an uncommon peripheral neuropathy associated with diabetes mellitus and characterised by profound weight loss and painful dysaesthesias over the limbs and trunk. The pathophysiological basis of this disorder remains unknown and there have been no published cases of recurrent[…][]

  • Forbes-Albright Syndrome

    […] syndromes with oral pigmentation, and in some cases may aid in earlier diagnosis of MAS.[] […] mucosa erythematous lesions9 Oral mucosa pigmented lesions9 Oral mucosa punctate erosive lesions9 Oral mucosa white lesions9 Oral ulcers acute Orbital lesions calcified Orbital[] OBSERVATIONS: We present 4 patients with MAS who developed oral mucosal pigmentation during childhood or early adulthood.[]

  • Polyostotic Fibrous Dysplasia

    Polyostotic fibrous dysplasia (PFD) is a non-hereditary congenital and benign disease of the bone. In PFD, fibrous-like tissues with immature osteogenesis replace the normal bone. The lesions may be mono- or polyostotic. PFD is associated with bone pain and fractures due to bone fragility. Polyostotic fibrous[…][]

  • Arsenic Poisoning

    In humans, as in most mammalian species, inorganic arsenic is methylated to methylarsonic acid (MMA) and dimethylarsinic acid (DMA) by alternating reduction of pentavalent arsenic to trivalent and addition of a methyl group from S-adenosylmethionine. The methylation of inorganic arsenic may be considered a[…][]

  • Dyskeratosis Congenita

    Dyskeratosis congenita (DC) is a rare inherited disorder characterized by reticular skin pigmentation, oral cavity leukoplakia, and nail dystrophy.[] […] dys·ker·a·to·sis con·gen·'i·ta [MIM*305000] nail dystrophy, oral leukoplakia, and reticular pigmentation of the skin, testicular atrophy with anemia progressing most commonly[] […] leukoplakia and abnormal skin pigmentation.[]

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