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77 Possible Causes for Orthohyperkeratosis

  • Actinic Keratosis

    Skin biopsy showed a hyperkeratotic stratum corneum with alternating areas of orthohyperkeratosis and parakeratosis, hypergranulosis, acanthosis, and minimal dysplasia confined[consultant360.com]

  • Ichthyosis Vulgaris

    The epidermis in this disorder characteristically displays non-specific orthohyperkeratosis.[ncbi.nlm.nih.gov] Histopathological analysis of IV reveals orthohyperkeratosis, reduced or absent keratohyalin granules, and decreased to absent stratum granulosum.[nursingcenter.com]

  • Palmoplantar Keratosis

    Histopathologic examination revealed orthohyperkeratosis within focal clavus‐like depressions of the epidermis and prominent hypergranulosis.[doi.org]

  • Prurigo Nodularis

    RESULTS: Highly characteristic for PN is the presence of thick compact orthohyperkeratosis; the hairy palm sign (folliculosebaceous units in nonvolar skin in conjunction with[ncbi.nlm.nih.gov] Histopathology Lesions of prurigo nodularis under histopathology can show thick, orthohyperkeratosis, irregular epidermal hyperplasia, and pseudoepitheliomatous hyperplasia[knowledge.statpearls.com] Some of the characteristic features of the cells include: Orthohyperkeratosis Irregular epidermal hyperplasia Pseudoepitheliomatous hyperplasia Superficial epithelial necrosis[symptoma.com]

  • Acanthosis Nigricans

    The changes of acanthosis nigricans are manifest by a mammillated, acanthotic epidermis with orthohyperkeratosis, and there is no significant inflammatory infiltrate (figure[dermatology.cdlib.org]

  • Confluent and Reticulated Papillomatosis

    Skin biopsy for histopathological examination revealed epidermal hyperplasia with lamellated orthohyperkeratosis and thickened granular layer.[ijdvl.com]

  • Peeling Skin Syndrome

    Photomicrograph showing hypergranulosis lamellated orthohyperkeratosis in the epidermis. An incomplete cleft is seen above the granular layer (H&E, 40).[ncbi.nlm.nih.gov] Figure 2 Photomicrograph showing hypergranulosis lamellated orthohyperkeratosis in the epidermis. An incomplete cleft is seen above the granular layer (H&E, 40).[casereports.bmj.com] Histopathological examination showed sparse superficial perivascular lymphocytic infiltrates with hypergranulosis and lamellated orthohyperkeratosis in the epidermis.[ncbi.nlm.nih.gov]

  • Pruritic Rash

    Histopathology results show orthohyperkeratosis, focal parakeratosis, irregular epidermal hyperplasia, and nonspecific dermal infiltrate such as macrophages, lymphocytes,[consultant360.com]

  • Peeling Skin Syndrome Type A

    Histopathological examination showed sparse superficial perivascular lymphocytic infiltrates with hypergranulosis and lamellated orthohyperkeratosis in the epidermis.[casereports.bmj.com] Histopathological examination showed sparse superficial perivascular lymphocytic infiltrates with hypergranulosis and lamellated orthohyperkeratosis in the epidermis.[docksci.com] Figure 2 Photomicrograph showing hypergranulosis lamellated orthohyperkeratosis in the epidermis. An incomplete cleft is seen above the granular layer (H&E, 40).[casereports.bmj.com]

  • Congenital Non-Neoplastic Nevus

    […] reminiscent of seborrheic keratosis, namely, comedo-like openings, irregular crypts and milia-like cysts as well as an opaque brown-yellowish coloration due to the pronounced orthohyperkeratosis[dermoscopy.org]

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