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41 Possible Causes for Orthokeratosis in Epidermis

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  • Parapsoriasis

    Histologic Features Thin orthokeratosis An epidermis of normal thickness containing atypical lymphoid cells singly and in collections Minimal spongiosis Vacuolar degeneration[dxpath.com]

  • Hyperkeratosis Lenticularis Perstans

    Histologic Features A thick laminated overlying orthokeratosis Depressed, flattened epidermis with hypogranulosis Epidermal hyperplasia at the periphery of the lesion Moderate[dxpath.com] Figure 3 Basket-weave orthokeratosis and an adjacent area showing thicker epidermis with a preserved granular layer.[aocd-grandrounds.org] The adjacent epidermis revealed preservation of granular layer with overlying basket-weave orthokeratosis (Fig 3 and Fig 4).[aocd-grandrounds.org]

  • Atrophic Patchy Alopecia

    […] surface and infundibular epidermis Lichen planus, hypertrophic Hypertrophic lichen planus is lichen simplex chronicus imposed on papules and plaques of conventional lichen[derm101.com] Lichen planus In addition to signs diagnostic of lichen planus in the upper part of the dermis, the dermoepidermal junction, and the epidermis, there also are evidences of[derm101.com] […] cleft between the infiltrate of lymphocytes and an epidermis whose base is slightly jagged and is both hypergranulotic and orthokeratotic Lichen planus The subepidermal space[derm101.com]

  • Lipoid Proteinosis

    Histologic Features Compact orthokeratosis Slight papillation of the epidermis Large masses of hyalin-like material running perpendicular to the skin surface in the papillary[dxpath.com]

  • Jadassohn-Lewandowsky Syndrome

    Histological Findings Histological examination of plantar hyperkeratosis plaques reveals an acanthotic epidermis with parakeratosis and orthokeratosis compatible with rapid[e-ijd.org]

  • Actinic Lichen Planus

    Histologic examination demonstrated an atrophic epidermis with mild hyperkeratosis and orthokeratosis (Figure 3).[mdedge.com] Both show a band of lymphocytes hugging the underside of the epidermis. True lichen planus shows no retained nuclei in the outer dead layer of skin (orthokeratosis).[bozemanskinclinic.com] […] the lower trunk and limbs and snake-like patterns on the scalp and face. 8 In histopathological examinations, linear lichen planus is identical to lichen planus, compact orthokeratosis[scielo.br]

  • Erythema Elevatum Diutinum

    Histologic Features Compact orthokeratosis of the volar skin with a normal epidermis and a narrow grenz zone A dense, diffuse dermal infiltrate consisting predominantly of[dxpath.com]

  • Familial Angiolipomatosis

    (A) Microscopic examination of haematoxylin and eosin (H&E) stained sections reveals hyper-orthokeratosis, flattening of the epidermis, and extensive sclerosis of reticular[medicaljournals.se]

  • Tinea Corporis

    BACKGROUND: Commonly described histologic 'clues' to the diagnosis of dermatophytosis include neutrophils in the stratum corneum and/or epidermis, compact orthokeratosis and[ncbi.nlm.nih.gov]

  • Subungual Fibroma

    […] with hyperkeratotic orthokeratosis Lesion merges with adjacent normal dermis Neural structures are absent or inconspicious Lacks adnexal structures Microscopic (histologic[pathologyoutlines.com] Dermatol 1985;12:816 ) Thickened collagen in dermis is oriented predominantly in the vertical direction Stellate stromal cells may be present Covered by variably acanthotic epidermis[pathologyoutlines.com] […] fibers perpendicularly arranged Acanthosis and massive orthokeratosis Thickened collagen Hyperkeratosis and acanthosis Proliferating fibroblasts and capillaries Compact orthokeratosis[pathologyoutlines.com]

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