Orthostatic Hypotension: Causes & Reasons

Possible Causes for Orthostatic Hypotension

Both types of syncope are associated with orthostatic hypotension and are nonlethal. [ncbi.nlm.nih.gov]

Mechanisms of orthostatic hypotension and tachycardia in patients with pheochromocytoma. Am J Hypertens 1996; 9:760–769. [clevelandclinicmeded.com]

Orthostatic Hypotension (2) Treatment Lie down Trendelenberg position NS Regulate medications 24. [slideshare.net]

Syncope

"Orthostatic Hypotension". [en.wikipedia.org]

In contrast, in patients with orthostatic hypotension due to autonomic failure, these cardiovascular homeostatic reflexes are chronically impaired. [accessmedicine.mhmedical.com]

Orthostatic Hypotension Orthostatic (upright) hypotension (low blood pressure when standing) can also cause fainting because blood has trouble going against gravity to reach [hopkinsmedicine.org]

Diabetic Autonomic Neuropathy

Hypertension in orthostatic hypotension and autonomic dysfunction. [nature.com]

First-line treatments include midodrine for orthostatic hypotension, prokinetic drugs for gastroparesis, broad-spectrum antibiotics for diabetic diarrhea, and sildenafil for [ncbi.nlm.nih.gov]

Treatment of diabetic orthostatic hypotension with alpha-agonists or fludrocortisone cause or aggravate supine hypertension. [mayoclinic.pure.elsevier.com]

Autonomic Neuropathy

We present a unique case of orthostatic hypotension as the sole feature of a CRMP-5 paraneoplastic autonomic neuropathy in a patient with small cell lung cancer. [ncbi.nlm.nih.gov]

The bladder problems tend to improve earlier than orthostatic hypotension. [ncbi.nlm.nih.gov]

CAN was assessed by 5 CARTs: the deep breathing test, Valsalva ratio, 30/15 ratio, handgrip and orthostatic hypotension test. [ncbi.nlm.nih.gov]

Hypovolemia

Prolonged capillary refill time (pressing on the nail) and orthostatic hypotension are not reliable signs of mild to moderate hypovolemia 5. [ehealthstar.com]

Orthostatic Hypotension Orthostatic hypotension is one of several signs and symptoms of hypovolemia. Hypotension is the medical term for low blood pressure. [brighthub.com]

References Reference.md (Hypovolemia definition) PMC (Preventing and treating orthostatic hypotension) Emedicine (Nephrotic syndrome) PubMed (Vasovagal syncope) Jamanetwork.com [ehealthstar.com]

Hypotension

Delayed orthostatic hypotension. [dizziness-and-balance.com]

Some medications may cause orthostatic hypotension. [newsnetwork.mayoclinic.org]

2) Orthostatic Hypotension 5-29 % of all causes syncope Aging changes in physiology that predispose to orthostatic hypotension: - decrease in B-adrenergic responsivenss - [unmc.edu]

Diabetic Neuropathy

Therapy with fluoxetine did not result in exacerbation of the orthostatic hypotension. [ncbi.nlm.nih.gov]

Symptomatic Treatment of Orthostatic Hypotension. [doi.org]

Previous therapy with desipramine resulted in exacerbation of the patient's orthostatic hypotension. [ncbi.nlm.nih.gov]

Shy-Drager Syndrome

Postural hypotension: a report of three cases. J Am Heart J 1925 ; 1 : 73 –86. ↵ Lewis P. Familial orthostatic hypotension. [jnnp.bmj.com]

Postural hypotension: a report of three cases. J Am Heart J1925;1:73–86. ↵ Lewis P. Familial orthostatic hypotension. Brain1964;87:719–27. ↵ Shy GM, Drager GA. [jnnp.bmj.com]

Dysautonomic Orthostatic Idiopathic Orthostatic Hypotension, Shy Drager Type Idiopathic Orthostatic Hypotension, Shy-Drager Type Orthostatic Hypotension, Dysautonomic Orthostatic [online-medical-dictionary.org]

Dysautonomia

Moderate sympathetic dysfunction causes absent late phase II and reduced phase IV responses and typically mild orthostatic hypotension. [thoracickey.com]

Hallmarks of generalized dysautonomia due to sympathetic failure are impotence (in men) and a fall in blood pressure during standing (orthostatic hypotension). [web.archive.org]

N Engl J Med 1993; 329:1449–55 Robertson D: The pathophysiology and diagnosis of orthostatic hypotension. [doi.org]

Autonomic Nervous System Disorder

hypotension (nOH) went a long way in giving them answers and hope for relief. [nohmatters.com]

Sometimes, orthostatic hypotension can cause a person to faint. [nyulangone.org]

If the changes are larger or last longer, the person may have orthostatic hypotension. [merckmanuals.com]

Renal Salt-Wasting Syndrome

All patients presented 2 to 4 months after starting cisplatin with severe orthostatic hypotension (mean orthostatic change in blood pressure, -37 ± 8 mm Hg) without preceding [annals.org]

hypotension which can result in fainting. [5] Other symptoms frequently associated with dysautonomia include headaches, pallor, malaise, facial flushing, constipation or [en.wikipedia.org]

In CSW, expect signs and symptoms of dehydration, including dry mucous membranes, poor skin turgor, tachycardia, orthostatic hypotension, weight loss, and a negative fluid [americannursetoday.com]

Pure Autonomic Failure

Lack of these features does not exclude the need to assess and investigate orthostatic hypotension and possible autonomic failure. [ncbi.nlm.nih.gov]

Idiopathic orthostatic hypotension, sometimes also referred to as Bradbury-Eggleston syndrome, falls into this general category. [emedicine.medscape.com]

Evaluation of Orthostatic Hypotension FIGURE 1. Algorithm for the evaluation of orthostatic hypotension. [aafp.org]

Cerebral Salt-Wasting Syndrome

He had signs of hypovolemia, such as orthostatic hypotension, dry mucosa, decreased skin turgor, hemoconcentration, contraction alkalosis, and high BUN/Cr ratio. [ncbi.nlm.nih.gov]

hypotension which can result in fainting. [en.wikipedia.org]

But now when you assess him, you find that he can't follow simple commands, has orthostatic hypotension, and is oliguric with dry mucous membranes. [journals.lww.com]

Amyloidosis

hypotension (or dizziness) and low blood pressure when standing Diarrhea and constipation How is amyloidosis diagnosed? [houstonmethodist.org]

hypotension No Response/Stable Disease Does not meet the criteria for autonomic neuropathy response or progressive disease Progressive Disease Worsening of symptomatic orthostatic [cibmtr.org]

Orthostatic hypotension can be disabling, and may result in falls and therefore fractures. [intechopen.com]

Dopamine Beta-Hydroxylase Deficiency

Pharmacologic distinction of different orthostatic hypotension syndromes. Neurology. 1981; 31 : 1–7. [doi.org]

Hypotension Completed NCT00555880 Phase 4 Midodrine hydrochloride;Placebo 2 Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study [malacards.org]

The treatment of orthostatic hypotension with dihydroxyphenylserine. Clin Neuropharm. 1991; 14 : 296–304. [doi.org]

Triple A Syndrome

Specific autonomic disturbances described in this syndrome include abnormal pupillary reflexes, poor heart rate variability, and orthostatic hypotension. [rarediseases.org]

There may also be signs of autonomic dysfunction with AAA, such as pupillary abnormalities, an abnormal reaction to intradermal histamine, abnormal sweating, orthostatic hypotension [ipfs.io]

Hereditary ATTR Amyloidosis

hypotension Recurrent urinary tract infections (due to urinary retention) Sexual dysfunction Sweating abnormalities Alternating bouts of diarrhea and constipation Peripheral [hattrguide.com]

Autonomic neuropathy is manifest by gastrointestinal symptoms of diarrhea with weight loss and orthostatic hypotension. [bu.edu]

hypotension), bladder problems, bowel problems, sexual dysfunction Gastrointestinal – Decreased appetite, diarrhea, nausea, stomach pain, weight loss Some ATTR variants are [amyloidosis-austria.at]

Hyponatremia

Patients presenting with orthostatic hypotension and normal plasma sodium concentrations are frequently admitted to the hospital with a diagnosis of dehydration. [annals.org]

同时专家们还提出了两个新概念，我觉得也很有意思：起始体位性低血压（initial orthostatic hypotension） Initial orthostatic hypotension is defined as a transient blood pressure decrease (40 mmHg systolic blood [news.medlive.cn]

New insights into orthostatic hypotension in multiple system atrophy: a European multicentre cohort study. [news.medlive.cn]

Autonomic Dysreflexia

Treatment of orthostatic hypotension with fludrocortisone acetate relieved these symptoms. [ncbi.nlm.nih.gov]

In addition to low baseline blood pressure and orthostatic hypotension, the patient developed episodes of autonomic dysreflexia during the acute stage after tetraplegia. [ncbi.nlm.nih.gov]

Table 9 Orthostatic hypotension in parkinsonian disorders Table 10 Examples of non-neurogenic causes of orthostatic hypotension. [jnnp.bmj.com]

Familial Dysautonomia

BACKGROUND: In patients with familial dysautonomia (FD), prominent orthostatic hypotension (OH) endangers cerebral perfusion. [ncbi.nlm.nih.gov]

Results: HUT showed orthostatic hypotension without compensatory tachycardia in FD patients but not in controls. [neurology.org]

hypotension as well as labile blood pressure that increases markedly during emotional excitement. [ncbi.nlm.nih.gov]

Pheochromocytoma

Orthostatic hypotension Reduced responsiveness of the vasculature to norepinephrine due to down-regulation of alpha-adrenergic receptors Orthostatic hypotension Reduced responsiveness [medicaljoyworks.com]

An adrenergically mediated process is suggested by the combination of paroxysmal hypertension, orthostatic hypotension and tachyarrhythmias. [cancertherapyadvisor.com]

The value of triad plus orthostatic hypotension was studied too. [jdmdonline.biomedcentral.com]

Mitral Valve Prolapse

In some people, blood pressure may fall below normal when they stand up (a disorder called orthostatic hypotension). [merckmanuals.com]

hypotension. [en.wikipedia.org]

Midodrine was approved in the United States by the Food and Drug Administration (FDA) in 1996 for the treatment of dysautonomia and orthostatic hypotension. [en.wikipedia.org]

Adrenal Insufficiency

Orthostatic hypotension and salt craving can be prominent in primary insufficiency due to aldosterone deficiency leading to profound volume depletion. [ime.acponline.org]

Clinical ManifestationsUnexplained hypotension, weight loss, fatigue.Primary and Sec AI Fatigue, weakness, anorexia, weight loss N/V/D, dizziness, orthostatic hypotension [slideshare.net]

Although there are classic clinical signs (eg, fatigue, orthostatic hypotension, hyperpigmentation, hyponatremia, hyperkalemia, and hypoglycemia) of adrenal insufficiency, [pedsinreview.aappublications.org]

Addison Disease

Orthostatic hypotension, fever, and hypoglycemia characterize acute adrenal crisis, whereas chronic primary adrenal insufficiency presents with a more insidious history of [ncbi.nlm.nih.gov]

hypotension, edema). [unboundmedicine.com]

Here are some key symptoms that can suggest Addison’s disease: When this condition first begins, you may experience fatigue, lightheadedness, and orthostatic hypotension [dummies.com]

Autoimmune Polyendocrine Syndrome Type 2

hypotension For celiac disease, symptoms are weight loss, steatorrhea, bloating, cramping, and malnutrition. [emedicine.medscape.com]

Despite the fact that hypoadrenalism is characterized by specific symptoms and signs (asthenia, fatigue, orthostatic hypotension, weight loss, nausea, arthralgia, anorexia [journals.sagepub.com]

She, frequently experienced symptoms and signs of orthostatic hypotension, with a systolic blood pressure of 80 -100mmHg. [austinpublishinggroup.com]

Hypovolemic Shock

Evaluation of Orthostatic Hypotension FIGURE 1. Algorithm for the evaluation of orthostatic hypotension. [aafp.org]

hypotension, which means there can be lowered blood pressure. [healthguidance.org]

hypotension, increased pulse pressure variation, or clinical signs). [pulmccm.org]

Heat Exhaustion

On examination, patients appear tired, are usually sweaty and tachycardic, and may have orthostatic hypotension. Mental status is intact, unlike in heatstroke. [msdmanuals.com]

Lambert-Eaton Syndrome

hypotension in these patients Keyword history 73%/2010 [openanesthesia.org]

hypotension. [ncbi.nlm.nih.gov]

[…] authors report a case of a 65-year-old woman with small cell lung cancer who had profound, progressive lower extremity weakness, intermittent blurred vision, a dry mouth, and orthostatic [ncbi.nlm.nih.gov]

Anticholinergic Toxicity

hypotension - this may be reversed by phenylephrine or methoxamine. lacks atropine's CNS effects & rel.lack of inhib. of ciliary beating; more potent bronchodilatory, dry [ozemedicine.com]

Additionally, anticholinergic toxicity can cause orthostatic hypotension (especially in the elderly), picking behavior, and can lead to seizures, coma, and even death. [foamcast.org]

hypotension (severe drop in systolic blood pressure when standing up suddenly) and significantly increased risk of falls in the elderly population. [14] Older patients are [en.wikipedia.org]

Dehydration

Patients presenting with orthostatic hypotension and normal plasma sodium concentrations are frequently admitted to the hospital with a diagnosis of dehydration. [doi.org]

hypotension). [merckmanuals.com]

[…] dehydration, the sensation of thirst may actually decrease and blood pressure can fall, causing light-headedness or fainting, particularly upon standing (a condition called orthostatic [merckmanuals.com]