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83 Possible Causes for Osmotic Fragility Increased

  • Third Trimester Pregnancy

    Abstract This prospective study on assessment of renal insufficiency in pregnancy induced proteinuric hypertension was carried out on 104 cases, in Bangabandhu Sheikh Mujib Medical University (former IPGM&R), Dhaka during period of August 1997 to September 1998. The objective of this study, to find out the[…][]

  • Hereditary Spherocytosis

    fragility: increased; basis for diagnostic testing Diagrams / tables Images hosted on other servers: Scatter diagram of CBC Treatment Splenectomy (prolongs survival of red[] Blood film showed about 70% spherocytes, reticulocytosis of 6.5%, increased osmotic fragility test and a negative direct antiglobulin test.[] Partial PK deficiency was associated with decreased red cell ATP content and markedly increased osmotic fragility.[]

  • Fetal Erythroblastosis

    fragility of the red cells may be greatly increased. [3], [18] As all other cell lines were in normal range with a low reticulocyte count since birth indicating a possible[] […] due to anti-M shows two features that resemble ABO hemolytic disease rather than Rh hemolytic disease: First, the DAT is only weakly positive or negative and second, the osmotic[]

  • Chronic Lymphocytic Leukemia

    We have investigated the role of immunophenotyping in distinguishing between leukemic B-cell lymphoproliferative disorders. Circulating cells from 666 cases were analyzed with a panel of markers by flow cytometry. The diseases included: chronic lymphocytic leukemia (CLL), 400; prolymphocytic leukemia, 22; hairy cell[…][]

  • Congenital Hemolytic Anemia

    Osmotic fragility of fresh blood was increased, and postsplenectomy blood showed a fraction of extremely fragile cells.[] The Type I cases showed the following features: normocytic or slightly macrocytic anemia with mild hypochromia and some stippling; a decreased or normal osmotic fragility[] The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.[]

  • Paroxysmal Nocturnal Hemoglobinuria

    Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired clonal disorder characterized by chronic complement-mediated hemolysis. The humanized anti-C5 antibody eculizumab binds to the C5 protein and suppresses hemolysis by inhibiting C5b-9 generation. Here, we report on a 27-year-old woman who was found to[…][]

  • Autoimmune Hemolytic Anemia

    A young female presented with acute abdominal pain of two days duration consistent with acute pancreatitis. During her stay in the hospital she had a sudden drop in hemoglobin to 6 g/dl without any overt blood loss. On evaluation, it was evident that she had acute pancreatitis, in addition to displaying features of[…][]

  • Malaria

    J Korean Med Sci. 2016 Sep;31(9):1499-502. doi: 10.3346/jkms.2016.31.9.1499. Author information 1 Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. 2 Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital,[…][]

  • Glycogen Storage Disease Type 1

    Abstract In glycogen storage disease type 1 (GSD1), children present with severe hypoglycemia, whereas the propensity for hypoglycemia may decrease with age in these patients. It was the aim of this study to elucidate the mechanisms for milder hypoglycemia symptoms in young adult GSD1 patients. Four patients with[…][]

  • Extensive Burns

    Abstract Classic determinants of burn mortality are age, burn size, and the presence of inhalation injury. Our objective was to describe temporal trends in patient and burn characteristics, inpatient mortality, and the relationship between these characteristics and inpatient mortality over time. All patients aged 18[…][]

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