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95 Possible Causes for Osmotic Fragility Increased

  • Hereditary Spherocytosis

    fragility: increased; basis for diagnostic testing Diagrams / tables Images hosted on other servers: Scatter diagram of CBC Treatment Splenectomy (prolongs survival of red[] Blood film showed about 70% spherocytes, reticulocytosis of 6.5%, increased osmotic fragility test and a negative direct antiglobulin test.[] Partial PK deficiency was associated with decreased red cell ATP content and markedly increased osmotic fragility.[]

  • Hereditary Elliptocytosis

    MCHC more than 36% C. increased osmotic fragility D. all of the above D. all of the above spherocytes on the peripheral smear MCHC more than 36% increased osmotic fragility[] fragility test Osmotic fragility is increased because of red cell membrane instability. [17] Autohemolysis test, the hypertonic cryohemolysis test, and the acidified glycerol[] Diagnosis requires demonstration of increased RBC osmotic fragility and a negative direct antiglobulin test.[]

  • Congenital Hemolytic Anemia

    Osmotic fragility of fresh blood was increased, and postsplenectomy blood showed a fraction of extremely fragile cells.[] The Type I cases showed the following features: normocytic or slightly macrocytic anemia with mild hypochromia and some stippling; a decreased or normal osmotic fragility[] The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.[]

  • Hexokinase Deficiency

    The erythrocyte osmotic fragility increased, and the autolysis test was normal or after the addition of glucose and ATP was partially corrected (Type I).[] osmotic fragility).[] Increased osmotic fragility may also occur in other red cell membrane disorders such as hereditary elliptocytosis, and in auto-immune hemolytic anemia.[]

  • Autoimmune Hemolytic Anemia

    Parvovirus B19 virus commonly causes subclinical infection, but it can prove fatal to the fetus during pregnancy and cause severe anemia in an adult with hemolytic diseases. We present the case of a woman with autoimmune hemolytic anemia who was diagnosed with parvovirus B19-induced transient aplastic crisis during[…][]

  • Extensive Burns

    Microalbuminuria, often referred to as the urinary albumin-creatinine ratio (ACR), is thought to be a reflection of increased capillary permeability associated with the systemic inflammatory response syndrome, and has been found to be predictive of outcome in several studies. Therefore, we explored the usefulness[…][]

  • Dravet Syndrome

    osmotic fragility Increased osmolarity index (Omin osmolality at which 50% of red blood cells hemolyze) Hereditary spherocytosis is inherited in an autosomal dominant manner[] […] concentration (MCHC) Presence of spherocytes and occasionally few ovalocytes and elliptocytes in the peripheral blood smear Significantly decreased or absent haptoglobin Mildly increased[]

  • Anemia due to Glutathione Metabolism Disorder

    Entry H00668 Disease Name Anemia due to disorders of glutathione metabolism Subgroup Glucose-6-phosphate dehydrogenase deficiency [DS: H01375 ] Glutathione peroxidase deficiency Gamma-glutamylcysteine synthetase deficiency Glutathione synthetase deficiency 5-oxoprolinase deficiency Description Anemia due to[…][]

  • Hemoglobin C Disease

    Of 148 adults with sickle cell hemoglobin C (SC) disease seen at Cook County Hospital and Clinics, Chicago, Illinois, eight patients had coexistent noninsulin-dependent diabetes mellitus. The clinical findings were notable for the paucity of retinal vascular changes. No patient showed proliferative diabetic retinopathy; one[…][]

  • Pyrimidine-5-Nucleotidase Deficiency

    Osmotic fragility increased Autohemolysis increased What is the treatment for Hereditary Stomatocytosis?[] Targeted or contracted speculated cells (Puddled Hb) MCV increases MCHC increases Osmotic fragility decreases What is the pathology of Hereditary Increase in Membrane Lecithin[] […] anisocytosis and poikilocytosis seen on smear Special Tests Osmotic fragility increased Autohemolysis increased Chemistry Indirect bilirubin increased Fecal and urine urobilinogen[]

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