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10 Possible Causes for Osteopenia and Osteoporosis, Sternal Tenderness

  • Vitamin D Deficiency

    Severe, prolonged vitamin D deficiency causes growth retardation and rickets in children and osteomalacia, osteopenia, and osteoporosis in adults.[bestpractice.bmj.com] Vitamin D deficiency causes rickets in children and will precipitate and exacerbate osteopenia, osteoporosis, and fractures in adults.[ncbi.nlm.nih.gov] It is often associated with decreased bone density such as osteopenia or osteoporosis.[gov.uk]

  • Ankylosing Spondylitis

    The prevalences of low BMD, osteopenia, and osteoporosis were significantly higher among AS patients than among controls (19.8%, 62.8%, and 5.7% vs. 4.7%, 33.0%, and 0%, respectively[ncbi.nlm.nih.gov] Metabolic bone disease : Osteopenia and osteoporosis may occur in patients with long-standing spondylitis, further increasing risk of fracture.[web.archive.org]

  • X-Linked Hypophosphatemia

    Endocr J. 2017 Mar 31;64(3):283-289. doi: 10.1507/endocrj.EJ16-0199. Epub 2016 Dec 27. Author information 1 Division of Genetic Research, Tokyo Metropolitan Children's Medical Center, Tokyo 183-8561, Japan. Abstract X-linked hypophosphatemia (XLH) is a group of rare disorders caused by defective proximal tubular[…][ncbi.nlm.nih.gov]

  • Familial Hypophosphatemia

    A case of young man with low back ache and heel pains who was examined in a rheumatology outpatient and diagnosed as familial hypophosphatemia (FH), probably X-linked (XL), is presented. FH is most commonly transmitted as XL. The role of PHEX gene and fibroblast growth factor 23 is also described.[ncbi.nlm.nih.gov]

  • Sternal Fracture

    Localized sternal tenderness was present in 68 (97.1%), external signs of contusion/ecchymosis in 33 (47.1%), and dyspnea in 10 (14.3%) patients.[ncbi.nlm.nih.gov] Insufficiency fractures caused by abnormally decreased bone density or weakened bone can occur spontaneously in patients with osteoporosis or osteopenia (particularly in older[emedicine.com] Acute, severe sternal pain that is worse with respiration with localized tenderness.[radiopaedia.org]

  • Hungry Bones Syndrome

    […] evaluated in patients with clinical histories of nephrolithiasis, nephrocalcinosis, osseous pain, subperiosteal resorption, and pathologic fractures, as well as in those with osteoporosisosteopenia[reumatologiaclinica.org] […] or osteoporosis. [8] A history of acquired racquet nails (brachyonychia) may be indicative of bone resorption. [9] Parathyroid adenomas are very rarely detectable on clinical[en.wikipedia.org] When you don’t get enough calcium, you increase your risk of developing disorders like: osteoporosis osteopenia calcium deficiency disease (hypocalcemia) Children who don’[healthline.com]

  • Pulmonary Disorder

    Point tenderness on palpation may signal underlying rib fracture or pleural inflammation.[msdmanuals.com] Other complications include osteopenia/osteoporosis, depression and anxiety, chronic pain, obstructive sleep apnea, renal stones, dialysis-dependent chronic kidney disease[msdmanuals.com] In cor pulmonale , a right ventricular impulse at the left lower sternal border may become evident and may be increased in amplitude and duration (right ventricular heave)[msdmanuals.com]

  • Dyskeratosis Congenita

    There was no edema, clubbing, icterus, lymphadenopathy or sternal tenderness. Thyroid gland was normal.[e-ijd.org] Osteoporosis and osteopenia have been reported. The contribution of prior treatment and co-morbid conditions to these complications is not known.[ncbi.nlm.nih.gov]

  • Autosomal Dominant Dyskeratosis Congenita 2

    There was no edema, clubbing, icterus, lymphadenopathy or sternal tenderness. Thyroid gland was normal.[e-ijd.org] Musculoskeletal: Osteopenia, osteoporosis, and avascular necrosis of the hips and shoulders.[dermatologyadvisor.com] osteopenia.[nature.com]

  • Autosomal Recessive Dyskeratosis Congenita Type 5

    There was no edema, clubbing, icterus, lymphadenopathy or sternal tenderness. Thyroid gland was normal.[e-ijd.org] osteopenia.[nature.com] […] in a separate study of familial and sporadic IPF. 49 Again, some family members in these IPF pedigrees had clinical features similar to DC, including anemia, cancer, and osteoporosis[nature.com]

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