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18 Possible Causes for Oxygen-Binding Capacity of Hemoglobin Decreased

  • Hypoxia

    When the hemoglobin concentration inside RBCs decreases, this also reduces the capacity of the blood to carry oxygen.[ncbi.nlm.nih.gov] This implies that fewer hemoglobin molecules (or oxygen-binding sites) are available for binding oxygen. There can be several causes of this.[ncbi.nlm.nih.gov] Another example is CO poisoning, in which there is virtually irreversible combination of CO with some heme-binding sites on the hemoglobin molecule.[ncbi.nlm.nih.gov]

  • Normocytic Normochromic Anemia

    […] iron-binding capacity hypochromic, microcytic, erythrocytes a decreased amount of hemoglobin in the blood a reduction in hemoglobin below normal hemoglobin Literally, however[innvista.com] […] levels are too low to provide for the oxygen demands of the body decreased or absent iron stores; decreased serum ferritin; low serum iron; low transferrin saturation; increased[innvista.com] , the reduction of circulating RBCs per cubic millimeter, the amount of hemoglobin per 100 ml, or the volume of packed red cells per 100 ml of blood a condition in which hemoglobin[innvista.com]

  • Carbon Monoxide Poisoning

    […] to hemoglobin molecules, thus displacing oxygen from the red blood cells and decreasing the capacity of the blood to carry oxygen to the cells of the body.[medical-dictionary.thefreedictionary.com] […] interferes with the transportation of oxygen and carbon dioxide by the blood. carbon monoxide poisoning a toxic condition in which carbon monoxide gas has been inhaled and binds[medical-dictionary.thefreedictionary.com]

  • NADH Cytochrome B5 Reductase Deficiency

    […] oxidation of the fetal hemoglobin molecule to methemoglobin (Hb FM), which has decreased oxygen-binding capacity.[findzebra.com] Hypoxia occurs due to the decreased oxygen-binding capacity of methemoglobin, as well as the increased oxygen-binding affinity of other subunits in the same hemoglobin molecule[flipper.diff.org] capacity of hemoglobin; Decreased hemoglobin oxygen saturation; Anemia (in some); Reticulocytosis (in some) LABORATORY ABNORMALITIES: Methemoglobinemia MISCELLANEOUS: Onset[findzebra.com]

  • Decreased Oxygen Carrying Capacity

    QuestionAnswer CO is the most common toxic inhalant and decreases the oxygen-carrying capacity of blood.[studystack.com] It can cause death even when it has a low concentration because it binds more easily to hemoglobin than oxygen. What is anemia?[quizlet.com] Learning Objectives Describe how oxygen is bound to hemoglobin and transported to body tissues Key Takeaways Key Points Hemoglobin is made up of four subunits and can bind[courses.lumenlearning.com]

  • Cyanosis

    ETIOLOGY AND PATHOGENESIS Methemoglobinemia decreases the oxygen-carrying capacity of blood, because the oxidized iron cannot reversibly bind oxygen.[medtextfree.wordpress.com] Moreover, when one or more iron atoms have been oxidized, the conformation of hemoglobin is changed so as to increase the oxygen affinity of the remaining ferrous heme groups[medtextfree.wordpress.com]

  • Traumatic Hemolytic Anemia

    Methemoglobin cannot bind oxygen, so the oxygen-carrying capacity of the blood is decreased.[emjournal.net] These drugs oxidize ferrous hemoglobin ( 2) to ferric hemoglobin ( 3), which is methemoglobin.[emjournal.net]

  • Acquired Toxic Hemolytic Anemia

    Methemoglobin cannot bind oxygen, so the oxygen-carrying capacity of the blood is decreased.[emjournal.net] These drugs oxidize ferrous hemoglobin ( 2) to ferric hemoglobin ( 3), which is methemoglobin.[emjournal.net]

  • Nitrite Poisoning

    This methemoglobin cannot bind oxygen, which decreases the capacity of the blood to transport oxygen so less oxygen is transported from the lungs to the body tissues, thus[curezone.org] However, when swallowed, they are converted to nitrites that can react with hemoglobin in the blood, oxidizing its divalent iron to the trivalent form and creating methemoglobin[curezone.org]

  • Carbon Monoxide-Induced Parkinsonism

    The binding of CO to hemoglobin results in the formation of a compound called carboxyhemoglobin (COHb). COHb does not transport oxygen.[firerescuemagazine.com] As COHb levels rise, the oxygen-carrying capacity of the blood progressively decreases.[firerescuemagazine.com] Thus, CO will quickly bind to available oxygen binding sites and will also displace previously bound oxygen.[firerescuemagazine.com]

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