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99 Possible Causes for PACA

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  • Antimetabolite

    […] initial studies using a microtiter assay show that CAV exhibits a 50% inhibitory concentration of approximately 2 mM against the human pancreatic adenocarcinoma cell line, MIA PaCa[ncbi.nlm.nih.gov] A statistically significant reduction in cell viability was observed when three different pancreatic cancer cell lines (BxPc-3, MIA PaCa-2 and PANC-1), cultured in an anaerobic[ncbi.nlm.nih.gov] HY-17026 Gemcitabine Inhibitor 99.80% Gemcitabine (NSC 613327;LY188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC[medchemexpress.com]

  • Abnormal Origin of the Pulmonary Artery

    Differential diagnosis PACA frequently occurs as an isolated form with or without patent arterial duct.[orpha.net] Clinical description PACA usually occurs in infant or in the newborn where it manifests by respiratory distress, recurrent respiratory infection, moderate to severe pulmonary[orpha.net] Genetic counseling PACA is usually non-syndromic and sporadic. However rare association with the 22q11.2 deletion syndrome and/or familial recurrence has been described.[orpha.net]

  • Pancreatic Carcinoma

    The cytotoxicity of MIT-NPs to human pancreatic cancer BxPC-3 and MIA Paca-2 cells was comparable to that of free MIT.[ncbi.nlm.nih.gov] , we found that the serum EGFL7 level in PC tissues was statistically higher than that in normal subjects (p 0.05), whereas inhibition of EGFL7 expression could decrease PaCa[ncbi.nlm.nih.gov] In vitro investigations with the pancreatic carcinoma cell lines BxPC-3 and MIA PaCa-2 revealed no significant differences to off-target cells in the half maximal inhibitory[ncbi.nlm.nih.gov]

  • Hepatic Echinococcosis

    Indeed, parasitic cysts were found in a Colombian paca ( Cuniculus paca , Figure 4 ) in 1975.[doi.org] In just a few years, a second indigenous South American echinococcal species had been discovered, and the life cycle of the parasite, involving the bush dog and the paca,[ncbi.nlm.nih.gov] (F2), and paca ( Cuniculus paca ) (F3). Data from reference 180.[doi.org]

  • Dicumarol

    To determine whether inhibition of NQO(1) would alter the malignant phenotype, MIA PaCa-2 pancreatic cancer cells were treated with a selective inhibitor of NQO(1), dicumarol[ncbi.nlm.nih.gov] EXPERIMENTAL DESIGN AND RESULTS: In the human pancreatic cancer cell line MIA PaCa-2, dicumarol decreased cell viability, as measured by the 3-(4,5-dimethylthiazol-2-yl)-2,5[ncbi.nlm.nih.gov]

  • Familial Pancreatic Carcinoma

    A single carrier of the NBS1 mutation was affected by PaCa. The occurrence of PaCa among the BRCA1 and PALB2 mutation carriers is already known [ 14, 15 ].[e-crt.org] A recent study evaluated the prevalence of these founder mutations among sporadic PaCa patients and showed that the risk of sporadic PaCa is associated with the Slavic founder[e-crt.org] Our previous study conducted among 383 PaCa patients reported that the Polish founder mutation in NBS1 (657del5) is associated with an increased risk of PaCa (OR, 3.80; p[e-crt.org]

  • Mepazine

    P (1-38), AMIDE, HUMAN, OVINE, RAT; PACA P (1-38), HUMAN, OVINE, RAT; PACA P (1-38) (HUMAN, SHEEP, RAT) 无 C203H331N63O53S1 详情 供应商 136134-68-4 PITUITARY ADENYLATE CYCLASE[ichemistry.cn] […] tal; PACA tal base; PACA tol; Pakatal; Paxital; Pecatal; Pecazine C19H22N2S 详情 供应商 540-43-2 2-Heptanamine,N-methyl-; Hexylamine,N,1-dimethyl- (6CI,7CI,8CI); 2-(N-Methyl)heptylamine[ichemistry.cn] […] piperidyl)methylphenothiazine; 10-[(1-Methyl-3-piperidyl)methyl]phenothiazine; III 2318; Lacumin; MPMP; Mepazin; Mepazine; Mepazine base; Meprazine; Mesapin; Nothiazine; P 391; PACA[ichemistry.cn]

  • Colchicine

    By increasing intracellular reactive oxygen species (ROS) levels, 4o induced endoplasmic reticular stress and mitochondrial dysfunction in MIA PaCa-2 cells.[ncbi.nlm.nih.gov] However, pancreatic cancer cell line MIA PaCa-2 was found to be more sensitive towards 4o and showed strong inhibition in concentration and time-dependent manner.[ncbi.nlm.nih.gov] Further 4o treatment induced mitotic arrest, altered the expression of cell cycle-associated proteins, and disrupted the microtubules in MIA PaCa-2 cells. 4o treatment caused[ncbi.nlm.nih.gov]

  • Eucalyptus

    F1 displayed significantly greater antioxidant activity in three different assays (p 50 93.11   3.43 μg/mL) against MIA PaCa-2 cells compared to the other four fractions ([ncbi.nlm.nih.gov] Apoptotic studies were performed using a caspase 3/7 assay in MIA PaCa-2 cells.[ncbi.nlm.nih.gov] The E. microcorys and Eucalyptus saligna extracts showed lower GI 50 values than the ethanolic Eucalyptus robusta extract in MIA PaCa-2 cells.[ncbi.nlm.nih.gov]

  • Kohlschütter-Tönz Syndrome

    Laboratório de Genética , Curitiba , Brazil 9 kbo-Kinderzentrum München gGmbH , Munich , Germany 10 Centre de Référence Anomalies du Développement et Syndromes Malformatifs PACA[jmg.bmj.com]

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