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686 Possible Causes for Painful Neuropathy, Progressive Polyneuropathy

  • Chronic Alcoholism

    Alcoholism can cause peripheral neuropathy, often because many alcoholics also have a thiamine deficiency, which can cause painful neuropathy of the extremities.[disabilitysecrets.com] Too much vitamin B6, however, may worsen peripheral neuropathy Pain medication Physical therapy Use of orthopedic appliances, such as orthotic devices, which may be covered[foundationforpn.org] It may be hard to distinguish nutrition-related neuropathies from alcoholic neuropathy. Symptoms & Signs (Not all symptoms and signs may be present.)[foundationforpn.org]

  • Diabetes Mellitus

    But for others, diabetic neuropathy can be quite painful and disabling. Diabetic neuropathy is a common and serious complication of diabetes.[mayoclinic.org] […] peripheral neuropathy (e.g. glove and stocking distribution sensory changes, Charcot arthropathy, neuropathic pain, mononeuritis multiplex, diabetic amyotrophy ) autonomic[radiopaedia.org] See Diabetic Neuropathy, Autonomic Neuropathy, Neuropathic Pain and its Management. See Diabetic Foot, Leg Ulcers, Painful Foot.[patient.info]

  • Vasculitis

    Neuropathic pain due to vasculitic neuropathy can be treated with anti-seizure medications, antidepressants, or analgesics including opiate drugs.[hopkinsmedicine.org] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] Symptoms The symptoms of vasculitic neuropathy depend on the type and location of the nerve fiber involved.[hopkinsmedicine.org]

  • Alcoholic Neuropathy

    Five patients suffering from painful alcoholic neuropathy showed severe painful sensory disturbance in their extremities.[ncbi.nlm.nih.gov] […] of alcoholic polyneuropathy.[en.wikipedia.org] All this is accompanied by the chronic pain typical in cases of peripheral neuropathy.[neuropathydr.com]

  • Familial Amyloid Polyneuropathy

    Neuropathic pain due to amyloid neuropathy can be treated with anti-seizure medications, antidepressants, or analgesics including opiate drugs.[hopkinsmedicine.org] Finnish-type familial amyloidosis (FAP-IV) is an autosomal, dominantly inherited disorder characterized by progressive polyneuropathy and lattice corneal dystrophy type II[ncbi.nlm.nih.gov] Araki S and Ando Y (2010) Transthyretin‐related familial amyloidotic polyneuropathyProgress in Kumamoto, Japan (1967–2010).[els.net]

  • Diabetic Polyneuropathy

    Sixty-one patients with type 2 diabetes and painful neuropathy, 19 patients with painless DPN, 25 patients with type 2 diabetes but no clinical evidence of neuropathy, and[ncbi.nlm.nih.gov] Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[ncbi.nlm.nih.gov] […] extremities and by flaccid paralysis. progressive hypertrophic polyneuropathy Déjérine-Sottas disease.[medical-dictionary.thefreedictionary.com]

  • Amyloidosis

    How can I cope with neuropathy? Peripheral neuropathy: Medications that may help to alleviate neuropathic pain include gabapentin, pregabalin and duloxetine.[amyloidosis.org.uk] Tafamidis is a TTR stabilizer that is orally administered and, by interfering with amyloid fibril formation and deposition, is capable of slowing progression of TTR polyneuropathy[ncbi.nlm.nih.gov] Specifically, hereditary ATTR amyloidosis with polyneuropathy (hATTR-PN), also referred to as familial amyloidotic polyneuropathy (FAP) is an inherited, progressive, life-threatening[web.archive.org]

  • Systemic Amyloidosis

    A 51-year-old female was diagnosed with AL amyloidosis after 20 months of investigation of small painful deformities of the feet.[ncbi.nlm.nih.gov] Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.[doi.org] Neuropathy Treatment of peripheral neuropathy symptoms: Medications that may help to alleviate neuropathic pain include gabapentin, pregabalin and duloxetine.[amyloidosis.org.uk]

  • Thiamine Deficiency

    Anorexia, nausea, vomiting, abdominal pain. Later features Paraesthesia, peripheral neuropathy, depressed tendon reflexes, loss of vibration sense.[patient.info] Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[ncbi.nlm.nih.gov] Other systemic symptoms include weakness, malaise, joint pain and swelling, edema, depression, and neuropathy.[cdc.gov]

  • Polyarteritis Nodosa

    Nervous system:Decreased alertness Peripheral neuropathy Muscle pain, numbness or tingling Tingling, numbness and pain in feet, legs, hands and arms Seizures Slurred speech[foundationforpn.org] Blurred vision Symptoms and complications that distress the nerves consist of: Tingling Peripheral neuropathy Pain in the extremities Numbness Lesions of the CNS or central[byebyedoctor.com] It is characterized by fever, abdominal pain, weight loss, neuropathy, and, if the kidneys are affected, hypertension, edema, and uremia.[medical-dictionary.thefreedictionary.com]

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