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211 Possible Causes for Painful Neuropathy, Progressive Polyneuropathy, Pruritus

  • Diabetes Mellitus

    But for others, diabetic neuropathy can be quite painful and disabling. Diabetic neuropathy is a common and serious complication of diabetes.[] […] outweighed by the benefits of reducing cardiovascular risk. [ 8 ] Presentation Patients with all types of diabetes may present with polyuria, polydipsia, lethargy, boils, pruritus[] Symptoms develop 30 min to 2 h after injection and include urticaria, angioedema, pruritus, bronchospasm, and anaphylaxis.[]

  • Chronic Alcoholism

    Alcoholism can cause peripheral neuropathy, often because many alcoholics also have a thiamine deficiency, which can cause painful neuropathy of the extremities.[] Generalised pruritus Generalised skin itching ( pruritus ) may occur due to the build up of poorly metabolised substances that stimulate nerve endings in the skin.[] Too much vitamin B6, however, may worsen peripheral neuropathy Pain medication Physical therapy Use of orthopedic appliances, such as orthotic devices, which may be covered[]

  • Vasculitis

    Neuropathic pain due to vasculitic neuropathy can be treated with anti-seizure medications, antidepressants, or analgesics including opiate drugs.[] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[] The lesions may be asymptomatic or associated with burning, pruritus, or pain.[]

  • Paraneoplastic Syndrome

    neuropathy.[] We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[] This 59-year-old man developed ophthalmoplegia, dysarthria, dysphagia, pruritus, ataxia, corticobulbar and corticospinal signs in association with prostate cancer.[]

  • Multiple Myeloma

    For patients who have neuropathy, pain can be a debilitating symptom.[] […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[] Her pruritus resolved, but the lesions persisted. Footnotes Competing interests: None declared. This article has been peer reviewed.[]

  • Diabetic Polyneuropathy

    Sixty-one patients with type 2 diabetes and painful neuropathy, 19 patients with painless DPN, 25 patients with type 2 diabetes but no clinical evidence of neuropathy, and[] Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[] […] urinary tract infection, urinary frequency or dribbling, erectile dysfunction, loss of libido, dyspareunia, vaginal dryness, anorgasmia Sudomotor (sweat glands) symptoms: pruritus[]

  • Systemic Amyloidosis

    A 51-year-old female was diagnosed with AL amyloidosis after 20 months of investigation of small painful deformities of the feet.[] Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.[] This case demonstrates an unusual presentation of primary systemic amyloidosis consisting of arthritis and intense debilitating pruritus without primary skin lesions for a[]

  • Thiamine Deficiency

    Anorexia, nausea, vomiting, abdominal pain. Later features Paraesthesia, peripheral neuropathy, depressed tendon reflexes, loss of vibration sense.[] Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[] There was no history of fever, pruritus of hand and feet, headache, hypertension, oliguria, edema, and visual disturbances.[]

  • Waldenstrom Macroglobulinemia

    Fatigue Unexplained weight loss Enlarged lymph nodes or spleen Numbness, weakness or other nervous system problems, pain in the hands or feet, sometimes called peripheral[] Neuropathy is typically slowly progressive, distal, symmetrical, and sensorimotor.[] This can lead to numbness or a painful “pins and needles” sensation in the feet and legs, which is called neuropathy.[]

  • Beriberi

    Individuals who have undergone bariatric surgery for weight loss and do not take the required vitamin supplements may develop symptoms of beriberi (painful neuropathy due[] The essential feature is a polyneuropathy. b. The muscles become progressively more wasted and weak, and walking becomes increasingly difficult. c.[] There was no history of fever, pruritus of hand and feet, headache, hypertension, oliguria, edema, and visual disturbances.[]

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