Painless Hematuria: Causes & Reasons

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Possible Causes for Painless Hematuria

Neoplasm of the Urinary Bladder

The main clinical presentation is gross painless hematuria, seen in almost 85% of patients when the diagnosis is made. [symptoma.com]

A 4-year-old boy visited our outpatient clinic with recurrent painless gross hematuria with blood clots. [e-ultrasonography.org]

The diagnosis is most often made incidentally during the evaluation of painless hematuria and the subsequent discovery of an urothelial neoplasm. [symptoma.com]

Papilloma of the Bladder

A 7-year-old male presented with intermittent painless hematuria. [ncbi.nlm.nih.gov]

They present with painless hematuria and occur as solitary mucosal nodules or sessile polypoid lesions 1 to 3 cm. [med-ed.virginia.edu]

The tumors are seen incidentally or present with painless hematuria. They arise as single isolated lesions but multiple and sequential lesions are not uncommon. [med-ed.virginia.edu]

Urinary Bladder Transitional Cell Carcinoma

Patients with transitional cell carcinoma of the bladder classically present with irritative voiding symptoms or painless hematuria. [ncbi.nlm.nih.gov]

Most patients with TCC display urinary signs and symptoms, predominantly painless hematuria. [symptoma.com]

The most typical symptom, painless hematuria, calls for further cystoscopy investigation, especially in high-risk patients (smokers, workers exposed to carcinogenic chemicals [symptoma.com]

Renal Pelvis Transitional Cell Carcinoma

A 56-year-old man with painless hematuria was found to have a papillary transitional cell carcinoma of the renal pelvis with an accompanying nodule composed of multinucleated [ncbi.nlm.nih.gov]

[…] gross hematuria throughout micturition Flank pain Urethral carcinoma Painless gross hematuria at the beginning of micturition Bladder outlet obstruction Irritative voiding [amboss.com]

hematuria” Risk factors Exposure to cyclophosphamide Phenacetin Chronic urinary stasis Smoking Metastasizes to Regional lymph nodes Liver Lung Bone Imaging findings IVU Enlarged [learningradiology.com]

Cystitis Cystica

However, in symptomatic cases, painless hematuria and various other symptoms such as dysuria, urinary frequency and urgency occur. [symptoma.com]

We describe the case of cystitis cystica in a 13 year-old boy who presented with painless hematuria and was suspected to be bladder neoplasm on imaging. [ingentaconnect.com]

A young man admitted with complaints of painless paroxysmal gross hematuria was found to have bilateral vesical masses involving the bladder base, trigone and ureteric orfices [ncbi.nlm.nih.gov]

Squamous Cell Carcinoma of the Bladder

Infrequently, it presents with microscopic hematuria. In either case, hematuria is usually painless. [symptoma.com]

hematuria can be microscopic or grossly visible irritative voiding symptoms frequency urgency dysuria Evaluation Gold standard cystoscopy with biopsy Radiography calcification [medbullets.com]

Painless hematuria is the most common presenting symptom of bladder cancer (occurring in approximately 85% of diagnosed cases). [clinicaladvisor.com]

Ureteral Carcinoma

[…] gross hematuria throughout micturition Flank pain Urethral carcinoma Painless gross hematuria at the beginning of micturition Bladder outlet obstruction Irritative voiding [amboss.com]

A typical sign is usually painless gross hematuria, often as an isolated symptom. [omicsonline.org]

Sickle Cell Nephropathy

Snapshot An 18-year-old African American man with a history of sickle cell trait presents with 1 week of painless gross hematuria. [medbullets.com]

RPN is usually discovered by radiologic investigation of patients with painless gross hematuria. [accessmedicine.mhmedical.com]

Hematuria and Proteinuria Hematuria Painless hematuria (microscopic, macroscopic, or gross) is a common symptom of sickle cell disease (SCD). [emedicine.medscape.com]

Renal Papillary Necrosis

Sickle cell disease should be considered in patients with unexplained hematuria. A 26-year-old healthy Greek woman was evaluated because of new-onset painless hematuria. [nejm.org]

Typical symptoms in both acute and chronic nephritis are painless hematuria (without RBC casts !) and pyuria. [amboss.com]

These findings are illustrated with a case of a 9-year old girl with sickle cell disease who was referred with painless gross hematuria. [ncbi.nlm.nih.gov]

Urethral Carcinoma

The fourth patient presented with painless hematuria and had a cystoscopy and biopsy of urethral polyps. [jhu.pure.elsevier.com]

[…] gross hematuria throughout micturition Flank pain Urethral carcinoma Painless gross hematuria at the beginning of micturition Bladder outlet obstruction Irritative voiding [amboss.com]

Patients often present with painless gross hematuria or irritative voiding symptoms, although some cases are incidentally detected ( microscopic hematuria on urinalysis ). [amboss.com]

Hereditary Pheochromocytoma-Paraganglioma

Painless hematuria could be observed if paragangliomas are located within the urinary bladder wall. [symptoma.com]

Urinary bladder PGL may be revealed by painless hematuria and blood pressure increase after micturition. [orpha.net]

Urothelial Ureter Papilloma

hematuria, gross or microscopic Diagnosis Imaging: ultrasound (USG) Cystoscopy: papillary / elevated lesions, variable size, often unifocal (Mod Pathol 2003;16:623) Biopsy [pathologyoutlines.com]

[…] gross hematuria is the most common presenting symptom in IUP, reported in up to 64% of patients.1,6,8,9,16 Patients may also have microscopic hematuria (6.8–15%), dysuria [ncbi.nlm.nih.gov]

[…] bladder, most commonly the posterior or lateral wall (Mod Pathol 2003;16:623) Etiology Unknown at this time but often associated with KRAS / HRAS mutations Clinical features Painless [pathologyoutlines.com]

Adenocarcinoma of the Ureter

CASE REPORT A 62-year-old male, presented with complaints of lower urinary tract symptoms, pain in right lower abdomen, off and on fever, and two episodes of painless hematuria [ncbi.nlm.nih.gov]

hematuria along with intermittent pain in the left flank. [afju.springeropen.com]

[…] by pseudostratified columnar epithelium and show characteristics of adenocarcinoma Full size image Case 3 A 57-year-old male non-smoker presented with three episodes of painless [afju.springeropen.com]

Urethral Nephrogenic Adenoma

Case report A 46-year-old female was seen for a consultation for intermittent painless gross hematuria for more than 1 month. [latunisiemedicale.com]

Urethral Urothelial Papilloma

hematuria, gross or microscopic Diagnosis Imaging: ultrasound (USG) Cystoscopy: papillary / elevated lesions, variable size, often unifocal (Mod Pathol 2003;16:623) Biopsy [pathologyoutlines.com]

Childhood Bladder Cancer

CASE REPORT A 12 year-old boy presented with painless intermittent macroscopic hematuria. [scielo.isciii.es]

Urachal Adenocarcinoma

Case reports Case 1 The patient was a 32-year-old man who noted painless hematuria with blood clots for 1 month. [spandidos-publications.com]

CASE SUMMARY A 49-year-old male presented to his primary care physician with painless, gross hematuria. [appliedradiology.com]

The clinical symptoms of these UC patients were shown below. 7 cases were painless gross hematuria, 2 cases were lower abdominal pain, 1 case had mucinuria and 1 patient had [xiahepublishing.com]

Ureteral Lymphoma

[…] gross or microscopic hematuria is commonly observed in patients presenting with ureteral carcinoma (13). [ncbi.nlm.nih.gov]

21 months (7) 52 F L HL NU + radiation Unknown (7) 12 M L HL NU + chemotherapy NED, 18 months (7) 52 M L HL PU Unknown (7) 54 M R HL NU + chemotherapy NED, 11 months (7) Painless [ncbi.nlm.nih.gov]

Nephrogenic Adenoma

Case report A 46-year-old female was seen for a consultation for intermittent painless gross hematuria for more than 1 month. [latunisiemedicale.com]

Benign Polyp of the Ureter

We report a 78-year-old female presented with intermittent painless gross hematuria initially suggestive of transitional cell carcinoma. [omicsonline.org]

Case report A 53-year-old woman was admitted to the Second Clinical Hospital of North Sichuan Medical College (Nanchong, China) with gross painless hematuria for ~2 years [spandidos-publications.com]

The presenting symptoms of fibroepithelial polyps are vague and non-specific, most common symptoms are gross painless hematuria and/or intermittent or recurrent flank pain [omicsonline.org]

Renal Tuberculosis

If lesions in the bladder prior to kidney tuberculosis bleeding, it was manifested as painless hematuria whole. 3. Pyuria incidence rate of about 20%. [tcmwell.com]

A male child aged 34 days presented with painless hematuria of 48 hours duration. He was born to a primigravida mother at term. [jiaps.com]

A 48-year-old man presented with painless left lateralizing macroscopic hematuria. [ncbi.nlm.nih.gov]

Renal Nutcracker Syndrome

We present a case of an 8-year-old boy who presented with painless hematuria for 2 months. [indjvascsurg.org]

Three days post-operatively, he presented a painless gross hematuria. [latunisiemedicale.com]

Conservative treatment with strict follow-up is recommended for patients with microscopic hematuria or intermittent short periods of painless gross hematuria, insignificant [ijcasereportsandimages.com]

Primary Amyloidosis

A 56-year-old man presented with a 1-year history of intermittent gross, painless hematuria. [ncbi.nlm.nih.gov]

This report describes a 49-year-old male with repeated painless gross hematuria, who underwent transurethral resection of a suspected bladder tumor. [ncbi.nlm.nih.gov]

Keywords: Amyloidosis, painless hematuria, urothelial cancer How to cite this article: Gupta P, Hanamshetti S, Kulkarni JN. [cancerjournal.net]

Subcapsular Kidney Rupture

and renal mass is the classic presentation Unenhanced CT followed by three-phase CT Enhancing renal mass Renal papillary necrosis Painful or painless hematuria Computed [aafp.org]

A 55-year-old woman presented with history of painless gross hematuria, urinary frequency and urgency for 3 months. [indianjcancer.com]

It can be painless, or pain can occur because of urinary obstruction from the sloughed cells. [aafp.org]

Chronic Hepatic Schistosomiasis

For Schistosoma haematobium in the chronic phase, painless hematuria is the classic symptom, and is frequently recurrent. [coursera.org]

Clinical features: i) Painless hematuria is the earliest symptom. ii) Other symptoms are, more or less, similar to Schistosoma mansoni. iii) Lesions in uterine cervix may [histopathology-india.net]

Benign Papilloma of the Ureter

They present with painless hematuria and occur as solitary mucosal nodules or sessile polypoid lesions 1 to 3 cm. [med-ed.virginia.edu]

Clinically, patients with IPB have symptoms similar to patients with urothelial cell carcinoma, and often present with intermittent and painless macroscopic hematuria or dysuria [academic.oup.com]

These tumors usually present with painless hematuria, dysuria, or bladder outlet obstruction, but they can be asymptomatic as demonstrated in one of our cases. [indianjcancer.com]

Allergic Interstitial Nephritis

Typical symptoms in both acute and chronic nephritis are painless hematuria (without RBC casts !) and pyuria. [amboss.com]

hematuria Often gross hematuria, as a consequence of red blood cell (RBC) ‘sickling’, vascular obstruction and RBC extravasation Usually UNILATERAL (LEFT >> RIGHT, 2nd to [renalandurologynews.com]

Drugs with low urine solubility precipitate within the renal tubules → tubular obstruction & toxicity to tubules Symptoms Painless hematuria Flank pain Sterile pyuria Peripheral [amboss.com]

Chronic Nephritis

Typical symptoms in both acute and chronic nephritis are painless hematuria (without RBC casts !) and pyuria. [amboss.com]

The male to female ratio in the U.S. is 6:1. 40-50% of patients present with painless macroscopic hematuria at the time of infectious illness such as pharyngitis and the hematuria [clinicaladvisor.com]

Bladder Malakoplakia

Recurrent Painless Hematuria Secondary To Malacoplakia Of The Urinary Bladder. Urol J. 2013;10(1):821-823. [casereports.in]

Case Report A twelve-year-old black female was admitted to the urology service in 1972, with a history of gross, total, painless hematuria, and frequency of micturition. [kundoc.com]

It can be asymptomatic, or presents as painless hematuria, urinary tract infection, septicaemia, hydronephrosis, acute renal failure or complications of end stage renal disease [casereports.in]

Leukoplakia of the Bladder

Often, painful hematuria is associated with infectious causes, nephrolithiasis, or both, whereas painless hematuria is associated with urologic cancers. [blogs.nejm.org]

Urologic causes of hematuria can be further subcategorized as painless versus painful and microscopic versus gross. [blogs.nejm.org]

Tags: glomerular hematurie, hematuria, painless hematuria, prostatic acinar carcinoma, prostatic ductal adenocarcinoma Posted in Physicians-In-Training | Permalink | Comments [blogs.nejm.org]