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56 Possible Causes for Pallor, patients possibly clinically asymptomatic, Variable Expressivity

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  • Orthostatic Hypotension

    We furthermore calculated within participant variability in SBP related to postural change, expressed as coefficient of variation.[ncbi.nlm.nih.gov] Don't have her stand if she develops signs and symptoms of hypotension, such as dizziness, light-headedness, or pallor while sitting.[journals.lww.com] These findings suggest that clinically asymptomatic orthostatic hypotension in Parkinson's disease patients may acutely worsen neuropsychological performances with possible[ncbi.nlm.nih.gov]

  • Cardiomyopathy

    The disorder is thought to be inherited in an autosomal dominant fashion with variable penetrance and variable expressivity.[emedicine.com] Affected individuals may also experience excessive sweating, fatigue, wheezing, and paleness of the skin (pallor).[rarediseases.org] […] findings Very variable, many patients remain asymptomatic Exercise-induced ventricular arrhythmias palpitations , syncope , possibly sudden cardiac death Atypical chest pain[amboss.com]

  • Asthma

    Asthma is a complex disorder that displays heterogeneity and variability in its clinical expression both acutely and chronically.[ncbi.nlm.nih.gov] In years to come it may be possible to identify patients with asymptomatic asthma and hence underlying inflammation by using more sensitive tests (eg impulse oscillometry[patient.info] The effect size is a dimensionless variable expressing the standardized difference (i.e., the mean difference divided by standard deviation) between, in our study, the mean[dx.doi.org]

  • Hypothyroidism

    Due to the rarity of the syndrome, the treatment strategies described are quite variable.[doi.org] Then there is pitting edema in lower extremities, especially around the ankles, coarse brittle hair, skin pallor and dryness. A goitre may develop.[symptoma.com] Clinical Considerations Patient Population Under Consideration This recommendation applies to nonpregnant, asymptomatic adults.[doi.org]

  • Pediatric Crohn Disease

    No outcome measures were expressed as continuous variables. Odds ratio, 95%CI, Forest and funnel plots were generated by Rev Man software.[ncbi.nlm.nih.gov] […] which may precede the onset of intestinal symptoms The most common cutaneous manifestations are erythema nodosum and pyoderma gangrenosum Skin examination may also reveal pallor[emedicine.medscape.com] The best clinical approaches to PSC include colonoscopic examination with a biopsy to identify a possible asymptomatic UC and/or cancer and a prevention colonoscopy program[doi.org]

  • Celiac Disease

    This cognitive involvement is variable in its expression, its duration and its prognosis ranging from transient and reversible subtle involvement to dementia itself.[ncbi.nlm.nih.gov] The child has failure to thrive , apathy, anorexia, pallor, generalized hypotonia, abdominal distention, and muscle wasting.[merckmanuals.com] The clinical significance of possible low grade histologic inflammation in asymptomatic individuals is not known.[clinicaladvisor.com]

  • Inflammatory Bowel Disease Type 1

    No outcome measures were expressed as continuous variables. Odds ratio, 95%CI, Forest and funnel plots were generated by Rev Man software.[ncbi.nlm.nih.gov] […] which may precede the onset of intestinal symptoms The most common cutaneous manifestations are erythema nodosum and pyoderma gangrenosum Skin examination may also reveal pallor[emedicine.com] The best clinical approaches to PSC include colonoscopic examination with a biopsy to identify a possible asymptomatic UC and/or cancer and a prevention colonoscopy program[doi.org]

  • Sickle Cell Disease

    Inflammation, haemolysis, microvascular obstruction and organ damage characterise the highly variable clinical expression of SCD.[ncbi.nlm.nih.gov] ASS: Inquire about noticeable increase in weakness or pallor, syncope, and sudden abdominal distention.[web.archive.org] Asymptomatic cholelithiasis is common and should be followed clinically. Prophylactic cholecystectomy is generally not recommended.[clinicaladvisor.com]

  • Vitamin B12 Deficiency

    Other newer areas of investigation that may provide better insights into the variability of expression of B 12 deficiency include genetic analysis and the effects of the microbiome[bloodjournal.org] A 9-year-old boy presented with knuckle hyperpigmentation and oral ulcers for 3 years, pallor and easy fatigability for 6 months, gait abnormalities for 3 months, and abnormal[ncbi.nlm.nih.gov] A total of 62 asymptomatic vitamin B12 deficiency patients and 40 healthy subjects were included in the study and both groups were subjected to Standardized Mini-Mental State[ncbi.nlm.nih.gov]

  • Anemia due to Glutathione Metabolism Disorder

    A pattern of autosomal dominant inheritance with variable expression is seen in up to 25% of cases. 26 It has been reported in identical twins. 27 The condition is caused[jcp.bmj.com] Individuals with hemolytic anemia can present with fatigue, pallor, irregular heartbeats, lightheadedness, and shortness of breath.[emedicine.medscape.com] The marked variability of expression of G-6-PD deficiency of heterozygotes is the result of certain features of the X-inactivation process.[g6pd.org]

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