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1,065 Possible Causes for Pallor, Pediatric Disorder, Splenomegaly

  • Hereditary Spherocytosis

    Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Pallor (100%), icterus (67%), undocumented fever (28%), splenomegaly (96%) and hepatomegaly (73%) were the most frequent findings. Cholelithiasis was observed in 26%.[ncbi.nlm.nih.gov] The 2003 Healthcare Cost and Utilization Project (HCUP) Kids’ Inpatient Database (KID), a robust and widely used measure of pediatric disorders, has estimated that the number[touchoncology.com]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] Physical examination reveals pallor and multiple ecchymoses on his arms, legs, and trunk.[doi.org] […] oncologist at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.[theguardian.com]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] […] diffuse rash) Splenomegaly occurs in 50% of patients Bone discomfort (especially in ribs, sternum, and tibia) Older adults may experience delirium, progressive weakness, and pallor[physio-pedia.com] Hasle H: Myelodysplastic and myeloproliferative disorders in children. Curr Opin Pediatr 19 (1): 1-8, 2007.[northshore.org]

  • Gaucher Disease

    CONCLUSION: HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] […] reactions, occurring in 2 or more patients, included abdominal pain, agitation, fever, chills, diarrhea, eczema, edema, hypertension, irritability, laryngeal edema, nausea, pallor[aetna.com] Society, Society for Pediatric Research, Society for Inherited Metabolic Disorders Disclosure: Nothing to disclose.[emedicine.com]

  • Splenic Rupture

    Splenomegaly Splenomegaly has traditionally been diagnosed by the physical exam finding of having a palpable spleen but in one study 16% of patients with such were found to[omicsonline.org] Pain in the upper left abdominal quadrant, hypotension, pallor, tachycardia and abdominal distention are main symptoms.[symptoma.com] In the presence of severe anemia with pallor and abdominal distension, particularly in the context of a difficult birth, an abdominal ultrasound must be urgently performed[ncbi.nlm.nih.gov]

  • Nephroblastoma

    It is also important to investigate “B” symptoms associated with any lymphadenopathy or splenomegaly. Laboratory tests can often be helpful in ambiguous cases.[aafp.org] Non-specific symptoms are present in less than 1/3 children: subfebrility, weakness, pallor, loss of appetite constipation, abdominal pain 10–30 % patients develop micro or[telemedicina.med.muni.cz] News & World Report ranks us among the top pediatric nephrology and cancer programs in the country.[choa.org]

  • Mucopolysaccharidosis

    […] trunk (dwarfism), dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver (hepatomegaly) or spleen (splenomegaly[en.wikipedia.org] […] was good Patient’s personal hygiene was well maintained Patients was well hydrated Absence of edema General appearance: - Coarse facial appearance - Flat nasal bridge - Pallor[slideshare.net] The mucopolysaccharidoses: a heterogeneous group of disorders with variable pediatric presentations. J Pediatr. 2004 May;144(5 Suppl):S27-34. Review.[ghr.nlm.nih.gov]

  • Precursor-Cell Lymphoblastic Leukemia

    Splenomegaly and thrombocytopenia were frequently observed more in CD200 patients. Increased frequency of CD34 was associated with CD200 and CD56 patients.[ncbi.nlm.nih.gov] Physical examination reveals pallor and multiple ecchymoses on his arms, legs, and trunk.[doi.org] I: The field of pediatrics -- pt. II: Growth, development and behavior -- pt. III: Behavioral and psychiatric disorders -- pt. IV: Learning disorders -- pt.[worldcat.org]

  • Sickle Cell Disease

    In two mouse SCD models, Berkeley and SAD, inhibition of red blood cell dehydration and sickling was achieved with correction of hematological parameters, splenomegaly, and[ncbi.nlm.nih.gov] ASS: Inquire about noticeable increase in weakness or pallor, syncope, and sudden abdominal distention.[web.archive.org] Elder and Jeremie Heath Estepp, Hematologic Disorders of the Eye, The Eye in Pediatric Systemic Disease, 10.1007/978-3-319-18389-3_11, (295-325), (2017).[doi.org]

  • Acute Leukemia

    Symptoms include splenomegaly, monocytosis with granulocytosis, and thrombocytopenia. leukemia cu tis leukemia with leukocytic invasion of the skin marked by pink, reddish[medical-dictionary.thefreedictionary.com] The first case is a 4-year-old girl who presented with pallor and abdominal enlargement.[ncbi.nlm.nih.gov] Overall, patients with Down syndrome compose approximately 10% of pediatric patients with AML.[clinicaladvisor.com]

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