Create issue ticket

123 Possible Causes for Pallor, Reticulocyte Count Decreased, Splenomegaly

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Abstract Pernicious anemia (PA) is an entity initially described in 1849 as a condition that consisted of pallor, weakness, and progressive health decline.[ncbi.nlm.nih.gov] Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] , and polychromatophilia and very elevated reticulocyte counts can occur. 263,264 The antiglobulin (Coombs) test usually is negative, but red cell autoantibodies can develop[patient-help.com]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org] Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly.[icd9data.com]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] Symptoms are referable to the specific cell line most affected and may include fatigue, weakness, pallor (secondary to anemia), increased infections and fever (secondary to[msdmanuals.com] We present a 2-year-old boy with splenomegaly, leukocytosis, thrombocytopenia, anemia, and excess myeloblasts with easily seen Auer rods, and marked dysgranulopoiesis and[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] The main clinical picture consists of a short time period with pallor, fatigue, fever, infections and hemorrhages. Presence of all these features is not compulsory.[orpha.net] […] diffuse rash) Splenomegaly occurs in 50% of patients Bone discomfort (especially in ribs, sternum, and tibia) Older adults may experience delirium, progressive weakness, and pallor[physio-pedia.com]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    On the one hand, anemia accounts for pallor, fatigue, and limited resistance to exercise.[symptoma.com] These conditions manifest in: Pallor, fatigue, reduced resistance to exercise, and dyspnea as symptoms of anemia Increased susceptibility to infections as a sign of leukopenia[symptoma.com]

  • Hereditary Spherocytosis

    Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[ncbi.nlm.nih.gov] At 1 year following partial splenectomy, mean hemoglobin significantly increased by 3.0 1.4 g/dL (n 52), reticulocyte count decreased by 6.6% 6.6% (n 41), and bilirubin level[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    […] symptoms Physical findings: Impaired growth and development in children Pallor of the mucous membranes Spoon-shaped nails with decreased capillary refill Angular stomatitis Splenomegaly[symptoma.com] A 19-month-old girl with a history of asthma and atopic dermatitis presented to her pediatrician because of parental concerns of pallor and fatigue.[ncbi.nlm.nih.gov] Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu]

  • Leukoerythroblastic Anemia

    Symptoms and Signs Myeloid metaplasia may result in splenomegaly, particularly in patients with storage diseases.[merckmanuals.com] A normal red blood cell will have an area of pallor in the center of it; in hypochromic cells, this area of central … pallor is increased.[answers.com] count- increased (10-15%) after 5-7 days Platelets- increased platelet production Stem cell suppression (environmental insult) causes genetically altered stem cell (express[quizlet.com]

Similar symptoms