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1,024 Possible Causes for Pallor, Splenomegaly

  • Hereditary Spherocytosis

    Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[ncbi.nlm.nih.gov] He had been suffering from repeated attacks of jaundice, pallor, and splenomegaly since he was 10 years old.[ncbi.nlm.nih.gov]

  • Heart Failure

    […] report is intended to sensitise pediatricians to consider systemic vasculitis with pulmonary hemorrhage in children with pulmonary hypertension even in the absence of severe pallor[ncbi.nlm.nih.gov] Increased adrenergic activity is manifested by tachycardia, diaphoresis, pallor, peripheral cyanosis with pallor and coldness of the extremities, and obvious distention of[emedicine.medscape.com] […] wheezing S 3 gallop and/or pulsus alternans Increased intensity of P 2 heart sound Hepatojugular reflux Ascites, hepatomegaly, and/or anasarca Central or peripheral cyanosis, pallor[emedicine.com]

  • Gastrointestinal Hemorrhage

    This is often due to pre-existing liver disease and splenomegaly.[geekymedics.com] Seek immediate medical care (call 911) for serious symptoms, pale skin or pallor and difficulty breathing, severe abdominal pain , vomiting blood or black material, or change[healthgrades.com] Other signs to look for are ascites and erythema (chronic liver disease) and splenomegaly and dilated abdominal wall veins (portal hypertension).[uspharmacist.com]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Abstract Pernicious anemia (PA) is an entity initially described in 1849 as a condition that consisted of pallor, weakness, and progressive health decline.[ncbi.nlm.nih.gov] Hepatomegaly and splenomegaly may be present.[patient.info]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org] Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly.[icd9data.com]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] Additional findings may include splenomegaly, gallop or arrhythmia, pericardial or pleural rubs, rales, pallor, acute septic monoarticular arthritis or delirium.[symptoma.com] Pallor was present and there were findings of erythematous lesions on the soles.[jpma.org.pk]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[ncbi.nlm.nih.gov]

  • Splenic Rupture

    Splenomegaly Splenomegaly has traditionally been diagnosed by the physical exam finding of having a palpable spleen but in one study 16% of patients with such were found to[omicsonline.org] Pain in the upper left abdominal quadrant, hypotension, pallor, tachycardia and abdominal distention are main symptoms.[symptoma.com] In the presence of severe anemia with pallor and abdominal distension, particularly in the context of a difficult birth, an abdominal ultrasound must be urgently performed[ncbi.nlm.nih.gov]

  • Childhood Acute Lymphoblastic Leukemia

    The child redeveloped splenomegaly and fever, and then suffered an acute decompensation with hypoxemia, tachypnea, splenomegaly, and cardiac gallop.[ncbi.nlm.nih.gov] Anemia may manifest as pallor, headache, fatigue, dizziness, decreased energy or exercise tolerance, and sometimes syncope.[clinicaladvisor.com] Other manifestations include bone pain and arthritis, hepatomegaly, splenomegaly, lymphadenopathy, extramedullary masses located in the abdomen (compression of neighboring[symptoma.com]

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