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340 Possible Causes for Pallor, Splenomegaly, Upper Abdominal Pain

  • Gastrointestinal Hemorrhage

    Clinical features of upper gastrointestinal bleeding Symptoms Abdominal pain – may be epigastric or diffuse Haematemesis – vomiting of bright red blood Coffee-ground vomit[geekymedics.com] Seek immediate medical care (call 911) for serious symptoms, pale skin or pallor and difficulty breathing, severe abdominal pain , vomiting blood or black material, or change[healthgrades.com] Symptoms associated with blood loss can include Fatigue Weakness Shortness of breath Abdominal pain Pale appearance Vomiting of blood usually originates from an upper GI source[emedicinehealth.com]

  • Primary Myelofibrosis

    Hepatosplenomegaly may cause upper abdominal pain, portal hypertension and ascites.[symptoma.com] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net]

  • Myeloproliferative Disease

    pain or discomfort, especially in the upper left side nosebleeds, bleeding from the gums, easy bruising, or intestinal bleeding symptoms of blood clots including strokes,[encyclopedia.com] CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com]

  • Chronic Myeloid Leukemia

    Approximately 5 months after the initiation of nilotinib for CML, he developed upper abdominal distension with intermitting abdominal pain, and based on abdominal computed[ncbi.nlm.nih.gov] Three of 4 TKI-treated patients did not reach complete hematologic response due to the persistence of thrombocytosis and/or splenomegaly.[ncbi.nlm.nih.gov] […] insidious, with a nonspecific “benign” stage (malaise, anorexia, weight loss) eventually giving way to accelerated or blast phases with more ominous signs, such as splenomegaly, pallor[msdmanuals.com]

  • Familial Myelofibrosis

    Treatment Splenomegaly and extramedullary haemopoiesis Medical treatment remains the treatment of choice for most patients with symptomatic splenomegaly.[onlinelibrary.wiley.com] The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Anemia is one of the hallmarks of pancytopenia and is associated with fatigue, pallor, and cyanosis. Children may also be tachypneic due to hypoxia.[symptoma.com]

  • Gastritis

    The chief symptoms are severe upper-abdominal pain, nausea, vomiting, loss of appetite, thirst, and diarrhea; the illness develops suddenly and subsides rapidly.[britannica.com] […] positive (negative IgG), CMV viral load of 5700 copies/mL (real-time PCR); autoimmunity study showed antiparietal cell antibodies; abdominal ultrasonography detected homogenous splenomegaly[ncbi.nlm.nih.gov] Pallor, sweating, and rapid (or "racing") heart beat.[web.archive.org]

  • Splenic Rupture

    Splenomegaly Splenomegaly has traditionally been diagnosed by the physical exam finding of having a palpable spleen but in one study 16% of patients with such were found to[omicsonline.org] Pain in the upper left abdominal quadrant, hypotension, pallor, tachycardia and abdominal distention are main symptoms.[symptoma.com] In this case, we report a 40 year old women, a healthy donor for her sister who has aplastic anemia, who had sharp left upper abdominal pain on the forth mobilization day.[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    Headache, myalgia, and abdominal pain Aplastic crisis can give rise to these symptoms. [3] Right upper abdominal pain, radiating to the back across the flanks, associated[explainmedicine.com] Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[ncbi.nlm.nih.gov]

  • Heart Failure

    […] report is intended to sensitise pediatricians to consider systemic vasculitis with pulmonary hemorrhage in children with pulmonary hypertension even in the absence of severe pallor[ncbi.nlm.nih.gov] […] girth and epigastric and right upper quadrant (RUQ) abdominal pain.[emedicine.medscape.com] […] wheezing S 3 gallop and/or pulsus alternans Increased intensity of P 2 heart sound Hepatojugular reflux Ascites, hepatomegaly, and/or anasarca Central or peripheral cyanosis, pallor[emedicine.com]

  • Cardiomyopathy

    Sarcoidosis may be suspected in patients with cardiomyopathy and lymphadenopathy, skin rashes, or splenomegaly.[clevelandclinicmeded.com] Affected individuals may also experience excessive sweating, fatigue, wheezing, and paleness of the skin (pallor).[rarediseases.org]

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