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895 Possible Causes for Pallor, Splenomegaly, Weight Loss

  • Heart Failure

    Metrics of diuretic efficacy such as natriuresis, urine output, weight loss, net fluid balance, or fractional sodium excretion, differ in their risk for measurement error,[ncbi.nlm.nih.gov] […] report is intended to sensitise pediatricians to consider systemic vasculitis with pulmonary hemorrhage in children with pulmonary hypertension even in the absence of severe pallor[ncbi.nlm.nih.gov] loss 4.5 kg in 5 days in response to treatment Minor criteria: · Bilateral ankle edema · Nocturnal cough · Dyspnea on ordinary exertion · Hepatomegaly · Pleural effusion[web.archive.org]

  • Gastrointestinal Hemorrhage

    This is often due to pre-existing liver disease and splenomegaly.[geekymedics.com] Weight loss and anorexia, with or without a change in stool, suggest a GI cancer. A history of cirrhosis or chronic hepatitis suggests esophageal varices.[merckmanuals.com] Seek immediate medical care (call 911) for serious symptoms, pale skin or pallor and difficulty breathing, severe abdominal pain , vomiting blood or black material, or change[healthgrades.com]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss.[ncbi.nlm.nih.gov] Abstract Pernicious anemia (PA) is an entity initially described in 1849 as a condition that consisted of pallor, weakness, and progressive health decline.[ncbi.nlm.nih.gov]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] loss (including ‘anorexia’, ‘weight loss’ and ‘anorexia/weight loss’), weakness/fatigue (including ‘weakness’, ‘fatigue’, ‘weakness/fatigue’), malaise/fatigue (including[doi.org] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] He consulted our hospital because of weight loss and fever. Computed tomography (CT) revealed renal infarction.[ncbi.nlm.nih.gov] Additional findings may include splenomegaly, gallop or arrhythmia, pericardial or pleural rubs, rales, pallor, acute septic monoarticular arthritis or delirium.[symptoma.com]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com]

  • Endocarditis

    PATIENT CONCERNS: A young woman, with a history of aortic stenosis, was admitted to our unit for a month of intermittent fever associated with a new diastolic heart murmur and splenomegaly[ncbi.nlm.nih.gov] In the acute form the symptoms (fever, malaise, fatigue, weight loss, anemia) are directly related to the presence of an active infection that runs its course within a few[infoplease.com] […] of appetite If the disease goes untreated for some time, further symptoms may appear: red spots on the body's trunk red eyes club fingers and toes heart murmurs paleness (pallor[medbroadcast.com]

  • Chronic Lymphocytic Leukemia

    One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] […] of appetite, weight loss, or night sweats Swollen lymph nodes Chemotherapy, including targeted medicines, are used to treat CLL.[nlm.nih.gov] We describe a case of a 77-year-old man who presented with fatigue, pallor and lower limb pain and weakness.[ncbi.nlm.nih.gov]

  • Subacute Bacterial Endocarditis

    Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] The diagnosis of subacute bacterial endocarditis (SBE) is suggested by a history of an indolent process characterized by fever, fatigue, anorexia, and unexplained weight loss[ncbi.nlm.nih.gov] On physical examination, normal findings can be observed or fever, pallor, tachycardia, and change in a murmur or a new regurgitant type may be detected.[symptoma.com]

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