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19 Possible Causes for Palmar Hyperlinearity

  • Atopic Dermatitis

    Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org] Keratosis pilaris/Ichthyosis/Palmar hyperlinearity 2. Atypical vascular responses 3. Perifollicular accentuation/Lichenification/Prurigo 4. Ocular/Periorbital changes 5.[omicsonline.org]

  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] Abstract Ichthyosis vulgaris (IV) is the most common hereditary disorder of cornification in humans, characterized by generalized fine scaling of the skin, palmar hyperlinearity[ncbi.nlm.nih.gov] hyperlinearity and keratosis pilaris.[ncbi.nlm.nih.gov]

  • Ichthyosis

    Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[campus.uni-muenster.de]

  • Acquired Ichthyosis

    The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and dry, scaly skin.[flipper.diff.org] The pictures below show scaly skin on trunk and limbs and palmar hyperlinearity. ( Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure[flipper.diff.org]

  • X-Linked Ichthyosis

    The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com] […] keratoderma in LK ( LOR ). ( f ) Palmar hyperlinearity in IV ( FLG ). ( g ) Generalized fine scaling phenotype with concomitant severe erythema in NS ( SPINK5 ). ( h ) Onychoschisis[ncbi.nlm.nih.gov] ) Moderate scaling phenotype in recessive X-linked ichthyosis ( STS ). ( c ) Large, brown scaling phenotype in ARCI ( TGM1 ). ( d ) Hyperkeratosis in KI ( KRT10 ). ( e ) Palmar[ncbi.nlm.nih.gov]

  • Parana Hard-Skin Syndrome

    […] of their palmar skin and xerotic fish scale on their legs * Many genetic conditions, such as the large family of ichthyoses (including X-linked ichthyoses, Netherton\'s disease[checkorphan.org] […] itch * Ichthyoses vulgaris –Very common cause of dry skin –A genetic defect in skin barrier function, leading to a higher risk of atopic dermatitis –Patients often have hyperlinearity[checkorphan.org]

  • Peeling Skin Syndrome Type A

    Palmar and plantar areas are spared or present erythema, slight thickening of the skin or palmar hyperlinearity. An underlying erythroderma is present.[sites.uclouvain.be]

  • Atopic Cataract

    We found a statistically significant correlation between minor criteria of AD like palmar hyperlinearity and combination of xerosis and Dennie-Morgan fold and the presence[ijdvl.com] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org] Of the 43 AD patients with ocular abnormalities, palmar hyperlinearity was present in nine (21.0%) whereas it was noted in only four (7.0%) of the 57 patients without ocular[ijdvl.com]

  • Congenital Ankyloblepharon

    Increased numbers and depth of skin lines on the palms may also occur (hyperlinearity). Hyperkeratosis may also affect the knees and elbows.[rarediseases.org] Dry, scaly patches of skin may form on the palms and soles (palmar-plantar hyperkeratosis) as well as tiny, hardened bumps (punctate keratoderma).[rarediseases.org]

  • Rapp-Hodgkin Syndrome

    Increased numbers and depth of skin lines on the palms may also occur (hyperlinearity). Hyperkeratosis may also affect the knees and elbows.[rarediseases.org] Dry, scaly patches of skin may form on the palms and soles (palmar-plantar hyperkeratosis) as well as tiny, hardened bumps (punctate keratoderma).[rarediseases.org]

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