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19 Possible Causes for Palmar Hyperlinearity

  • Atopic Dermatitis

    Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org] Keratosis pilaris/Ichthyosis/Palmar hyperlinearity 2. Atypical vascular responses 3. Perifollicular accentuation/Lichenification/Prurigo 4. Ocular/Periorbital changes 5.[omicsonline.org]

  • Acquired Ichthyosis

    The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and dry, scaly skin.[flipper.diff.org] The pictures below show scaly skin on trunk and limbs and palmar hyperlinearity. ( Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure[flipper.diff.org]

  • Ichthyosis

    Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[campus.uni-muenster.de]

  • Atopic Cataract

    We found a statistically significant correlation between minor criteria of AD like palmar hyperlinearity and combination of xerosis and Dennie-Morgan fold and the presence[ijdvl.com] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org] Of the 43 AD patients with ocular abnormalities, palmar hyperlinearity was present in nine (21.0%) whereas it was noted in only four (7.0%) of the 57 patients without ocular[ijdvl.com]

  • Lamellar Ichthyosis Type 2

    When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[medicaljournals.se]

  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] hyperlinearity and keratosis pilaris.[ncbi.nlm.nih.gov] Ichthyosis vulgaris (IV) is the most common hereditary disorder of cornification in humans, characterized by generalized fine scaling of the skin, palmar hyperlinearity with[ncbi.nlm.nih.gov]

  • Generalized Follicular Keratosis

    It is characterized by palmar hyperlinearity, keratosis pilaris and a fine scale that is most prominent over the lower abdomen, arms, and legs.[nectarmutation.org]

  • Recessive X-Linked Ichthyosis

    The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com] Two sons exhibited variable phenotypic severity of XLI with palmar hyperlinearity, where both displayed concurrent heterozygous FLG mutations and concomitant STS microdeletions[journals.plos.org]

  • X-Linked Ichthyosis

    The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com]

  • Congenital Non-Bullous Ichthyosiform Erythroderma ARCI 10

    When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[medicaljournals.se]

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