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3,032 Possible Causes for Palmar Hyperlinearity, Peripheral Rash, Skin Thickening

  • Atopic Dermatitis

    Skin thickening and plaque formation is dependent on habitual scratching.[emedicine.com] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] AD is commonly referred to as the itch that rashes; the associated pruritus may be significant, even in the absence of significant rash.[pediatrics.aappublications.org]

  • Ichthyosis Vulgaris

    Symptoms may include any of the following: Dry skin, severe Scaly skin ( scales ) Possible skin thickening Mild itching of the skin The dry, scaly skin is usually most severe[nlm.nih.gov] The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] As older skin cells build up on the skin’s surface, the skin thickens and becomes scaly.[wederm.com]

    Missing: Peripheral Rash
  • Sunburn

    Those include the production of more melanin, skin thickening and signaling DNA repair systems that try to correct for mutations before they are carried forward, says Heather[scientificamerican.com] With repeated exposure to UVR, the skin thickens, primarily due to epidermal hyperplasia with thickening of the stratum corneum.[emedicine.com] The body will readily redistribute its existing melanin in response to UVA exposure—which results in immediate skin darkening—but UVB rays are better at triggering several[scientificamerican.com]

    Missing: Palmar Hyperlinearity
  • Ichthyosis

    As older skin cells build up on the skin’s surface, the skin thickens and becomes scaly.[wederm.com] Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[campus.uni-muenster.de] Symptoms Dry skin, severe Scaly skin ( scales ) Possible skin thickening Mild itching of the skin The dry, scaly skin is usually most severe on the legs.[nicklauschildrens.org]

    Missing: Peripheral Rash
  • Photosensitivity Disorder

    Long-term effects of photodermatitis include chronic skin thickening and scarring, and increased risk of skin cancer in patients with a genetic source of their dermatitis.[healthcoachmd.com] […] which are overexposed to UV light Pain, erythema, and swelling in affected areas Chills, headache, fever, and nausea may occur Long-term effects include chronic skin thickening[medicalfoxx.com] Low dose ambient sunlight exposure may be associated with improvement via a hardening process of skin thickening and pigmentation.[copublications.greenfacts.org]

    Missing: Palmar Hyperlinearity
  • X-Linked Ichthyosis

    Dermatological examination revealed that the skin over the patient's entire body was dry and coarse, with thickening and scaling of the skin in the extensor side of the extremities[ncbi.nlm.nih.gov] The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com] The thickening skin leads to a hardening and eventual cracking of the thickened skin, forming the characteristic pattern of scales.[transcend7.com]

    Missing: Peripheral Rash
  • Eosinophilic Fasciitis

    We describe a woman who presented with unilateral progressive skin thickening.[ncbi.nlm.nih.gov] Clinical presentation includes peripheral eosinophilia, symmetrical skin thickening with subcutaneous tissue induration of the extremities and rashes developing acutely over[ncbi.nlm.nih.gov] Examination of a full-thickness skin biopsy revealed an inflammatory process and fascial changes consistent with eosinophilic fasciitis.[ncbi.nlm.nih.gov]

    Missing: Palmar Hyperlinearity
  • Pityriasis Circinata

    Toyama A skin disease marked by the appearance of localized and circumscribed patches of thickened skin with lichenification, becoming scaly, without inflammatory changes,[whonamedit.com] hyperlinearity; there was no significant association with intrinsic atopic dermatitis.[findzebra.com] Variant presentations include peripheral distribution of the rash; facial involvement may be seen in children.[patient.info]

  • Impetigo

    Surrounding skin is also thickened and macerated as a result of occlusive and damp footwear. FIGURE 3.[aafp.org] Surrounding skin is also thickened and macerated as a result of occlusive and damp footwear. Until fairly recently, there was no effective treatment for onychomycosis.[aafp.org] Markedly thickened and deformed nail in a patient with onychomycosis, or tinea unguium.[aafp.org]

    Missing: Palmar Hyperlinearity
  • Erythema Infectiosum

    Thickened plaques with a lichenified appearance may be seen in more severe cases.[aafp.org] Persons with parvovirus B19 infection are no longer contagious when the rash appears because viremia has cleared by this point.[aafp.org] Once the fever resolves, an erythematous macular to maculopapular rash usually appears, starting on the trunk and spreading peripherally.[aafp.org]

    Missing: Palmar Hyperlinearity

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