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18 Possible Causes for Palmar Hyperlinearity, Pruritus, Skin Thickening

  • Atopic Dermatitis

    Skin thickening and plaque formation is dependent on habitual scratching.[emedicine.medscape.com] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] been used in clinic to relieve pruritus of atopic dermatitis patients.[ncbi.nlm.nih.gov]

  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] General approaches to management focus on reducing inflammation and pruritus as well as preventing xerosis.[ncbi.nlm.nih.gov] Symptoms may include any of the following: Dry skin, severe Scaly skin ( scales ) Possible skin thickening Mild itching of the skin The dry, scaly skin is usually most severe[nlm.nih.gov]

  • Ichthyosis

    Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[medizin.uni-muenster.de] Clinical measures included the Ichthyosis Area Severity Index (IASI), which integrates erythema (IASI-E) and scaling (IASI-S); transepidermal water loss; and pruritus.[ncbi.nlm.nih.gov] As older skin cells build up on the skin’s surface, the skin thickens and becomes scaly.[wederm.com]

  • X-Linked Ichthyosis

    Dermatological examination revealed that the skin over the patient's entire body was dry and coarse, with thickening and scaling of the skin in the extensor side of the extremities[ncbi.nlm.nih.gov] The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com] Universal erythroderma and pruritus are characteristic, and ectropion of variable degree is usually present.[medical-dictionary.thefreedictionary.com]

  • Peeling Skin Syndrome Type A

    Palms and soles are spared or may show redness and mild skin thickening or hyperlinearity. Underlying erythroderma is present.[orpha.net] Palmar and plantar areas are spared or present erythema, slight thickening of the skin or palmar hyperlinearity. An underlying erythroderma is present.[sites.uclouvain.be] Meanwhile, skin peeling is seen as a symptom in the following ailments: Erythroderma where the skin thickens and flakes.[suncoastsalts.com]

  • Acquired Ichthyosis

    The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and dry, scaly skin.[flipper.diff.org] In such cases, there is often an associated background erythema, and sometimes pruritus.[skincareguide.ca] Symptoms Symptoms may include any of the following: Dry skin, severe Scaly skin ( scales ) Possible skin thickening Mild itching of the skin The dry, scaly skin is usually[mountsinai.org]

  • Parana Hard-Skin Syndrome

    […] syndrome is a rare genetic skin disorder characterized by very early-onset of progressive skin thickening over the entire body (except for eyelids, neck and ears), progressively[malacards.org] […] of their palmar skin and xerotic fish scale on their legs * Many genetic conditions, such as the large family of ichthyoses (including X-linked ichthyoses, Netherton\'s disease[checkorphan.org] Orpha Number: 2812 Disease definition Parana hard skin syndrome is a rare genetic skin disorder characterized by very early-onset of progressive skin thickening over the entire[rarediseases.info.nih.gov]

  • Atopic Cataract

    Our continually developing society has resulted in increased incidence of atopic dermatitis, characterized by itchiness; eczematous lesions; and dry, thickening skin with[crstodayeurope.com] We found a statistically significant correlation between minor criteria of AD like palmar hyperlinearity and combination of xerosis and Dennie-Morgan fold and the presence[ijdvl.com] Soaks in sodium bicarbonate or colloidal oatmeal (Aveeno) can be used to treat pruritus.[aafp.org]

  • Follicular Mucinosis

    (Definition/Background Information) Alopecia mucinosa is a rare inflammatory condition of hair-bearing skin, resulting in a thickening of skin that is accompanied by hair[dovemed.com] hyperlinearity without FLG mutations.[researchmap.jp] […] erythrokeratodermas and related disorders Keratodermas Kro Dariers disease and HaileyHailey disease Daniel Hohl Theodora Mauro and leanPhilippe Gorog Mosaicism and linear lesions Pruritus[books.google.com]

  • Congenital Ankyloblepharon

    ., extension of lesions onto the dorsal aspect of the foot) of blisters, erosions, and subsequent skin thickening is possible and may be secondary to trauma, edema, or secondary[dermatologyadvisor.com] Increased numbers and depth of skin lines on the palms may also occur (hyperlinearity). Hyperkeratosis may also affect the knees and elbows.[rarediseases.org] Treat pruritus with sedating antihistamines Keep a high index of suspicion for infection.[clinicaladvisor.com]

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