Palpable Purpura: Causes & Reasons

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Possible Causes for Palpable Purpura

Vasculitis

These spots can usually be felt by the examiner's fingertips, hence the descriptor "palpable". The image below is a classic example of palpable purpura. [web.archive.org]

Abstract Cutaneous leukocytoclastic vasculitis (LCV) is type of small vessel vasculitis that commonly presents as palpable purpura involving the lower extremities and buttocks [ncbi.nlm.nih.gov]

These spots can usually be felt by the examiner’s fingertips, hence the descriptor “palpable”. This is a classic example of palpable purpura. [hopkinsvasculitis.org]

Leukocytoclastic Vasculitis

Palpable purpura in lower limb was commonest presentation. Majority were idiopathic LCV. [nepjol.info]

[…] leu·ko·cy·to·clas·tic vas·cu·li·tis cutaneous acute vasculitis characterized clinically by palpable purpura, especially of the legs, and histologically by exudation of the [medical-dictionary.thefreedictionary.com]

Leukocytoclastic vasculitis (LCV), a disease characterized by inflammation of the small vessels, presents with palpable purpura, especially in the lower extremities. [ncbi.nlm.nih.gov]

Henoch-Schönlein Purpura

The criteria selected by a classification tree method were similar: palpable purpura, age less than or equal to 20 years at disease onset, biopsy showing granulocytes around [ncbi.nlm.nih.gov]

The classic tetrad of signs and symptoms include palpable purpura, arthralgia, abdominal pain and renal disease. [ncbi.nlm.nih.gov]

In contrast, patients who experienced relapses had a longer duration of the first episode of palpable purpura than those without relapses (palpable purpura lasting >7 days [ncbi.nlm.nih.gov]

Idiopathic Cryoglobulinemia

Cryoglobulin deposition causes a vasculitis that leads to petechiae and palpable purpura. [aafp.org]

Cutaneous vasculitis with palpable purpura, especially in the lower extremities, should suggest cryoglobulinemia. [rheumaknowledgy.com]

Hypergammaglobulinemic purpura is a vasculitic purpura that primarily affects women. Recurrent crops of small, palpable purpuric lesions develop on the lower legs. [merckmanuals.com]

Polyarteritis Nodosa

Feels like there is an outbreak of vasculitis recently at the SFVA with a few morning reports on palpable purpura and it’s characteristic finding on pathology: leukocytoclastic [ucsfmed.wordpress.com]

PANpable: Palpable purpura is seen in PAN. That's all! -IkaN [medicowesome.com]

Livedo vascular pattern typical of cutaneous polyarteritis nodosa Expected results of diagnostic studies In the case of palpable purpura the cutaneous biopsy will show leukocytoclastic [dermatologyadvisor.com]

Churg-Strauss Syndrome

She became afebrile after 4 days, normotensive after 4 weeks, and her palpable purpura disappeared after 6 weeks. [mja.com.au]

palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. [patient.info]

She had conjunctival pallor, gangrene involving all fingertips of the left hand, palpable purpura on the anterior aspect of the left leg, and 3/5 grade motor weakness of the [mja.com.au]

Cryoimmunoglobulinemic Syndrome

[…] findings  Biopsy ... http://medknow.net/teachingfiles/FTP/test 1/2011 MMI RPGN.ppt presentation ... • RF high • + palpable purpura (leukocytoclastic vasculitis ) • Dx: biopsy [docpile.net]

One or more skin lesions including palpable purpura, ulcers, digital gangrene, and areas of necrosis occur in 69-89% of these mixed disease cases (see attached photograph) [en.wikipedia.org]

[…] of the MC (Fig. 8, 9, 10 ); patients with mild-moderate symptoms, such as palpable purpura, are particularly sensitive to the smallest variations of daily steroid dosage [ojrd.biomedcentral.com]

Subacute Bacterial Endocarditis

The case of a patient who had palpable purpura on his lower extremities due to Lactobacillus-caused subacute bacterial endocarditis is reported. [ncbi.nlm.nih.gov]

Physical examination revealed palpable purpura, mild hypertension, hepatosplenomegaly, and a holosystolic cardiac murmur (Levine 2/6). [ncbi.nlm.nih.gov]

Palpable purpura may also be seen. Imaging may reveal septic pulmonary infarcts, mycotic aneurysms, and stroke. [visualdx.com]

Hypocomplementemic Vasculitis

There was scleral erythema, urticaria on the torso, palpable purpura on the legs, and swelling and tenderness of the hand joints. A diagnostic procedure was performed. [nejm.org]

Physical exam Palpable purpura is pathognomonic for vasculitis. Palpable purpura consists of elevated, nonblanching erythematous lesions. [bobbybukamd.com]

Palpable purpura and oral ulcers are common cutaneous manifestations of Wegener’s granulomatosis. [bobbybukamd.com]

Immune Complex-Mediated Small Vessel Vasculitis

(HSP) is closely associated with what other disease What are the diagnostic criteria for Henoch-Schonlein Purpura (HSP) need 2/4: Age < 20 years Palpable purpura Bowel angina [quizlet.com]

Vasculitis manifests in types II and III cryoglobulinemic patients with a triad of arthralgias, myalgias, and palpable purpura. [ime.acponline.org]

Purpuric lesions are not always palpable to the touch, and the existence of palpable purpura does not necessarily imply an IC-mediated pathophysiology; pauci-immune forms [musculoskeletalkey.com]

Rheumatoid Arteritis

purpura. [thecurbsiders.com]

[…] in extremities, upper extremity claudication, aortitis, aortic aneurysm Medium vessels: supply gut → abdominal pain, testes → pain, infarct Small vessels: Skin → causing palpable [thecurbsiders.com]

Rocky Mountain Spotted Fever

Vasculitis is marked by palpable purpura rather than petechiae. Drug eruptions will have a history of exposure. [visualdx.com]

On admission, she had petechiae in some areas and blanching erythematous papules in others, but no palpable purpura. [dx.doi.org]

Kawasaki Disease

The dermatological manifestations include palpable purpura, ulcers or gangrenous-like pyoderma lesions. [web.archive.org]

Skin lesions occur in only 20 to 50% of the patients, and palpable purpura is the most common manifestations. [web.archive.org]

In Sjögren syndrome, cutaneous vasculitis may be manifested in 20% of the patients as palpable purpura ( Figure 6 ), ecchymosis and urticaria. [web.archive.org]

Acute Bacterial Endocarditis

Palpable spleen Patients may have had non-specific symptoms (e.g. malaise, low-grade fever) for several weeks or even months, and may not have any of the specific signs. [almostadoctor.co.uk]

Unknown murmurs Splenomegaly (40%) Coxiella infection – this particular bacterium will often caused a considerably enlarged liver and spleen Clubbing (10%) General fatigue Purpura [almostadoctor.co.uk]

Bacterial Endocarditis

Palpable spleen Patients may have had non-specific symptoms (e.g. malaise, low-grade fever) for several weeks or even months, and may not have any of the specific signs. [almostadoctor.co.uk]

Gram-Negative Septicaemia

BACKGROUND: Neonatal sepsis remains an important cause of neonatal morbidity and mortality. Tools to rapidly predict antibiotic resistance in neonatal sepsis would be extremely valuable. OBJECTIVES: To develop quantitative polymerase chain reaction (qPCR) primer/probe sets that can rapidly detect antibiotic[…] [ncbi.nlm.nih.gov]

Infective Endocarditis

Cardiovasc Revasc Med. 2017 Sep;18(6S1):19-22. doi: 10.1016/j.carrev.2017.03.005. Epub 2017 Mar 7. Author information 1 Guthrie Clinic/Robert Packer Hospital, Sayre, PA, 18850. Electronic address: safinmc@gmail.com. 2 Guthrie Clinic/Robert Packer Hospital, Sayre, PA, 18850. Abstract Acute myocardial infarction (MI) in the[…] [ncbi.nlm.nih.gov]

Purpura

Skin manifestations include palpable purpura, livedo reticularis, ulcers, and distal gangrene. [mdedge.com]

Evaluation and therapeutic outcome of palpable purpura. Indian J Dermatol Venereol Leprol [serial online] 2001 [cited 2019 Aug 5];67:320-3. [ijdvl.com]

On physical examination, he still had palpable purpura of the legs. There was no swelling, but his joints were still tender to palpation. [mdedge.com]

Systemic Vasculitis

There is presence of skin vaculitis with palpable petechiae or purpura. [en.wikipedia.org]

These spots can usually be felt by the examiner’s fingertips, hence the descriptor “palpable”. This is a classic example of palpable purpura. [hopkinsvasculitis.org]

Drugs most commonly implicated are penicillin, sulphonamides and thiazide diuretics. [13] There is presence of skin vaculitis with palpable petechiae or purpura. [en.wikipedia.org]

Pseudomonas Infection

2015 ICD-9-CM Diagnosis Code 041.7 Pseudomonas infection in conditions classified elsewhere and of unspecified site 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 041.7 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 041.7 should only be used[…] [icd9data.com]

Staphylococcal Septicemia

A previously healthy 5-year-old girl developed staphylococcal septicemia. Initially, cardiovascular failure with mitral insufficiency and purulent pericarditis dominated the clinical picture. Peripheral thromboembolic phenomena, meningitis, osteomyelitis, and persistent septicemia were subsequently encountered during[…] [ncbi.nlm.nih.gov]

Septic Embolus

General Considerations Age Majority Predisposed IV drug abusers Alcoholism Immunodeficiency CHD Dermal infection (cellulitis, carbuncles) Sources Tricuspid valve endocarditis Most common cause in IV drug abusers Pelvic thrombophlebitis Infected venous catheter or pacemaker wire Arteriovenous shunts for hemodialysis[…] [learningradiology.com]

Cryoglobulinemia

Keys to Diagnosis: Palpable purpura in a dependent distribution is most suggestive of cryoglobulinemia. [rheumaknowledgy.com]

Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration. [dermpedia.org]

Cardinal Findings: Palpable purpura may be present on the lower extremities and rarely extends above the waist. [rheumaknowledgy.com]

Cutaneous Vasculitis

We describe 4 patients who presented with palpable purpura, arthralgia or arthritis, leukopenia, and antineutrophil cytoplasmic antigen (ANCA) positivity most likely as a [ncbi.nlm.nih.gov]

Palpable purpura was seen in 49.4% and frequently involved the lower limbs (50.6%). [ncbi.nlm.nih.gov]

From the third day of symptoms onwards, the patient noticed the appearance of cutaneous lesions in the lower limbs with palpable purpura and erythematous papules. [ncbi.nlm.nih.gov]

Cryoglobulinemic Vasculitis

A 53-year-old woman presented with recurrent episodes of palpable purpura affecting the lower legs. [jaad.org]

Physical exam revealed palpable purpura on the dorsum of both feet. [mushare.marian.edu]

Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration. [dermpedia.org]

Necrotizing Arteritis

Physical exam Palpable purpura is pathognomonic for vasculitis. Palpable purpura consists of elevated, nonblanching erythematous lesions. [bobbybukamd.com]

Palpable purpura. If patients have this in isolation, it is most likely due to cutaneous leukocytoclastic vasculitis. [en.wikipedia.org]

Classification criteria for Henoch-Schönlein purpura include palpable purpura (mandatory criterion) in the presence of at least one of following 4 features: Diffuse abdominal [emedicine.medscape.com]

Microscopic Polyangiitis

On physical exam, there is palpable purpura and urticarial plaques on the lower extremities and several skin nodules. Wheezes are heard on lung exam. [medbullets.com]

purpura, abdominal pain, myalgias, arthralgias, mild hypertension Birmingham Vasculitis Activity Score (BVAS, online calculator): useful for determining disease activity [pathologyoutlines.com]

purpura, abdominal pain, myalgias, arthralgias, mild hypertension Birmingham Vasculitis Activity Score (BVAS, online calculator ): useful for determining disease activity [pathologyoutlines.com]

Hyperglobulinemic Purpura

Wallach Date: Oct, 1995 Palpable purpura is a cutaneous manifestation of several diseases. [drplace.com]

Causes of Palpable purpura Note: Image search may contain inaccuracies Churg-Strauss syndrome Cryoglobulinaemia Erythema multiforme Henoch-Schoenlein purpura Leukocytoclastic [xdiagnosis.net]

Palpable purpura and livedo reticularis can occur in some patients. There is presence of skin vaculitis with palpable petechiae or purpura. [diki.pl]

Rickettsia Infection

Author affiliations: *The Australian Rickettsial Reference Laboratory, Geelong, Victoria, Australia ; †Warwick Hospital, Southern Downs Health Services District, Warwick, Queensland, Australia ; The Torres Strait islands are scattered between Cape York in northeastern Australia and Papua New Guinea. Darnley (Erub)[…] [doi.org]

Enterobacter Infection

Angiosarcoma is a rare, aggressive, malignant endothelial neoplasm with a variable clinical presentation. The authors describe a case of angiosarcoma involving the eyelid that was complicated by a superimposed Enterobacter infection. Following positive cultures for E. aerogenes and multiple biopsies suspicious but not[…] [ncbi.nlm.nih.gov]